Fidest – Agenzia giornalistica/press agency

Quotidiano di informazione – Anno 34 n° 19

Enrollment in First MRgFUS Essential Tremor Feasibility Trial Completed

Posted by fidest press agency su mercoledì, 4 gennaio 2012

English: Common effects of ionizing radiation ...

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Tirat Carmel, Israel. InSightec Ltd, the global leader in MR guided Focused Ultrasound (MRgFUS) therapy, announced today that it has completed enrollment in the world’s first feasibility study evaluating the use of MRgFUS for treatment of Essential Tremor, using ExAblate® Neuro at University of Virginia , Charlottesville, Virginia. Fifteen patients underwent a non-invasive ExAblate treatment to evaluate safety and initial effectiveness of this investigational device. Most patients, who suffered for at least 10 years, experienced tremor improvement and no severe adverse events. They are being followed up for three months. Patient videos can be viewed here: http://bit.ly/sRpXno , http://bit.ly/tWaOl3ExAblate Neuro, pioneered by InSightec, combines high intensity focused ultrasound for deep accurate lesioning of the brain, with continuous realtime MR guidance for visualizing brain anatomy, planning and monitoring treatment and outcome. The lesioning is performed through an intact skull with no incisions or ionizing radiation. Additional research using MRgFUS for chronic neuropathic pain,targeted drug delivery, and sonothrombolysis for acute ischemic stroke is described in the January issue of Neurosurgical Focus devoted to MR guided focused ultrasound applications for central nervous system disorders.
Essential tremor, a very common movement disorder, affects millions of people worldwide. They have difficulty performing everyday tasks like drinking, eating, dressing, and writing. One third do not respond to medication, and may consider surgery. These have well recognized risks: high doses of ionizing radiation, complications and side effects from invasive surgery. MRgFUS was investigated as an alternative for these medically refractory patients.

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