Fidest – Agenzia giornalistica/press agency

Quotidiano di informazione – Anno 32 n° 259

Archive for 2 aprile 2013

CIE Tours Cities on Travel Hotlist

Posted by fidest press agency su martedì, 2 aprile 2013

Dublin, PRNewswire The Beatles Story in Liverpool is one of the hottest visits on several CIE Tours’ programs TripAdvisor.com, the online travel site, surveyed users’ opinions and reviews in order to compile their cities hot list. Here they reviewed the up-and-coming, the unexpected, and the freshly updated among some lesser-known but still sparkling cities. Three United Kingdom cities – Glasgow, Belfast, and Liverpool – have been named among the top-ten trendy spots to set down your suitcase in Europe this year. All three of these cities have upgraded their attractiveness to travellers, and all have something unique to offer. Good luck for potential travellers, too: All three are amply covered in a wide range of tour offerings from CIE Tours International, the premier packager for holidays in Ireland, England, Scotland and Wales. “We’re especially proud to say that we’ve known all along how special these cities are,” says CIE Tours president Brian W. Stack. “Our tours give visitors the very best of Liverpool, Glasgow and Belfast.” Take a CIE Tours’ trip that includes one or two of these cities, and you’ll understand their winning ways.
Liverpool: This Northern English birthplace of the Beatles always pleases. On a CIE Tours’ package, you’ll see the Fab Four’s favourite hangouts and special spots and also visit The Beatles Story, an attraction covering every aspect of their music.
Glasgow: A pedestrian-friendly city, Glasgow is an easy trip from its better-known Scottish sibling, Edinburgh. On a CIE Tour, you’ll hit the highlights, from the shopping and restaurant mecca of Sauchiehall Street to the fascinating newly-designed Riverside Museum of Transport and Travel, where you will marvel at all things with wheels and engines.
Belfast: In this Northern Ireland city, CIE Tours includes a trip to the amazing Titanic Belfast. This futuristic tourist attraction, which echoes the doomed White Star liner’s four hulls, is located on the same docks where Titanic itself was built.
Like all CIE Tours’ holidays, travel packages are all-inclusive, encompassing airport transfers; deluxe coach transportation; luxury hotel accommodation, taxes and porterage fees; and all admission fees; as well as most meals, special attractions and evening entertainment.

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Enstar Group Limited Completes Acquisition of U.S. and Canadian Closed-Life Insurance Operations From HSBC Finance

Posted by fidest press agency su martedì, 2 aprile 2013

Hamilton, Bermuda, (GLOBE NEWSWIRE) — Enstar Group Limited (Nasdaq:ESGR) announced today that one of Enstar’s wholly-owned subsidiaries completed the previously announced acquisition from Household Insurance Group Holding Company of HSBC Insurance Company of Delaware and Household Life Insurance Company of Delaware, as well as its three subsidiary insurers, on March 31, 2013. Household Insurance Group Holding Company is a subsidiary of HSBC Holdings plc.The HSBC companies acquired added approximately $1.4 billion in total cash and investments to Enstar’s balance sheet. As previously disclosed, the base purchase price of $181 million was rolled forward under the terms of the stock purchase agreement based upon changes to the capital and surplus of the acquired entities arising from the operation of the business prior to closing. The amount paid at closing was approximately $155.7 million and was financed in part by a drawing under Enstar’s revolving credit facility.
Enstar, a Bermuda company, acquires and manages insurance and reinsurance companies in run-off and portfolios of insurance and reinsurance business in run-off, and provides management, consultancy and other services to the insurance and reinsurance industry.

Posted in Economia/Economy/finance/business/technology, Estero/world news | Contrassegnato da tag: , , , | 10 Comments »

Global Nuclear Medicine

Posted by fidest press agency su martedì, 2 aprile 2013

Dallas, PRNewswire The radioisotopes market is categorized into diagnostic and therapeutic applications. The diagnostic market consists of PET and SPECT technologies, while the therapy market comprises of beta emitters and brachytherapy seeds. The SPECT market accounted for a major share of the diagnostic segment in 2012. Significant radioisotopes in the SPECT diagnostic market are Tc-99m, Tl- 201, Ga-67, and I-123, while PET market is dominated by F-18, and Rb-82. The therapy market is led by I-131, Sm-153, Re-186, Y-90, and Lu-177. Alpha emitters are being developed and considered for cancer treatment, however not available commercially. It is estimated that Tc-99m diagnostic procedures are expected to increase by more than 15% in mature markets of North America, Europe, Japan, the Republic of Korea, and Oceania between 2010 and 2030, however shortage of Mo-99/Tc-99m has been a threat to this industry. The scheduled shutdown of the NRU reactor in 2016 and OSIRIS in France in 2018 is a major risk for manufacturers in the near future. Companies have increased the production of thallium to meet the shortage, as it is the most commonly used substitute for technetium-99 in cardiac-stress tests, conducted to evaluate the functioning of coronary arteries. Radiopharmaceuticals in neurological applications such as Alzheimer’s disease, Parkinsons disease, and dementia are also being preferred by practitioners besides conventional treatment. Further, upcoming radioisotopes such as Ra-223 (Alpharadin) and Ga-68 possess huge potential for clinical applications. Increasing use of SPECT and PET scans, technical advancements in equipment and other factors such as rising awareness of radiopharmaceuticals among physicians, alpha radioimmunotherapy based targeted cancer treatment, and ready availability of nuclear medicine market from cyclotrons have driven the market. High cost of devices using radioisotopes, short half-life, lack of good manufacturing practices, and stringent regulatory approvals are major hurdles to growth of the market. North America is the dominant market for diagnostic radioisotopes with close to half of the market share. The U.S. is the largest consumer market for radiopharmaceuticals, while Canada is one of the largest producers of Tc-99m. Processors such as Nordion, Inc., Covidien Plc., and NTP Radioisotopes Pty Ltd. run reactors that are involved in the irradiation of U-235 to make crude isotopes. They follow various strategies to achieve sustainable growth, one of which is shifting to Low Enriched Uranium (LEU) from High Enriched Uranium (HEU). These key players were mainly involved in strategic agreements and contracts with other institutes and players, while generator manufacturers followed several strategies to maintain a sustainable supply chain. The stable isotopes market was less than $150 million in 2012 and poised to grow at more than 10% CAGR in the next 5 years. Carbon-13 commanded the largest share of the global stable isotope market in 2012; however deuterium and oxygen show tremendous potential to grow in the near future. The market was dominated by two players, Cambridge Isotope Laboratories (CIL) (U.S.) and Isotec (Sigma Aldrich) (U.S.) in 2012 jointly contributing more than 90% to the global revenue.
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