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Quotidiano di informazione – Anno 33 n° 244

Archive for 27 giugno 2018

Malattie autoimmuni, scoperta nuova terapia con nanovescicole da staminali

Posted by fidest press agency su mercoledì, 27 giugno 2018

Uno studio tutto italiano pubblicato su Scientific Reports mostra un nuovo approccio per il trattamento delle malattie autoimmuni e infiammatorie, che utilizza nanovescicole, strutture che sono in grado di trasportare e rilasciare molecole terapeutiche, ottenute da cellule staminali mesenchimali. Le terapie attualmente a disposizione per i pazienti con malattie autoimmuni sono in grado di rallentare l’evoluzione della malattia ma non di portare a una guarigione. Il nuovo trattamento basato su nanovescicole è invece stato in grado, tramite l’inibizione dell’attivazione dei linfociti T, di impedire la formazione di focolai infiammatori e di danni tissutali nel sistema nervoso centrale nell’encefalomielite sperimentale autoimmune, il modello di sclerosi multipla più utilizzato.«I fattori scatenanti tale patologia non sono noti con certezza ma numerose evidenze cliniche e sperimentali indicano che alla base vi è una reazione del sistema immunitario che individua quale bersaglio dei suoi linfociti il rivestimento dei neuroni, la mielina, compromettendone così la capacità di condurre gli impulsi elettrici. All’infiltrazione nel tessuto cerebrale dei linfociti T è correlata la comparsa dei segni clinici e patologici di disfunzione del sistema nervoso centrale tipici della sclerosi multipla» spiegano i ricercatori, guidati da Bruno Bonetti, direttore dell’Unità operativa complessa Neurologia A dell’Azienda Ospedaliera Integrata di Verona, in un comunicato stampa. Utilizzando tecniche di microscopia intravitale, il gruppo di lavoro è riuscito a mostrare che le nanovescicole possono bloccare la migrazione dei linfociti circolanti all’interno del cervello. In tutte le malattie infiammatorie il primo passo della riposta immunitaria è rappresentato dalla migrazione delle cellule immunitarie circolanti dai vasi sanguigni nei tessuti sede della patologia. Gli autori sottolineano che quando si prendono in considerazione malattie infiammatorie non infettive, come le malattie autoimmuni, il processo infiammatorio e la migrazione dei leucociti non hanno un ruolo di difesa dell’organismo, ma un ruolo patologico critico, e provocano un danno tissutale. «L’inibizione del traffico leucocitario costituisce quindi un approccio terapeutico molto potente nelle malattie autoimmuni e l’utilizzo della terapia a base di nanovescicole potrebbe impedire l’entrata di cellule leucocitarie dannose nei tessuti presi come bersaglio dal sistema immunitario» concludono i ricercatori. (fonte: doctor33 – Sci Rep. 2018. doi: 10.1038/s41598-018-25676-2 https://www.ncbi.nlm.nih.gov/pubmed/29748664)

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Fleet and Cog Partner to Secure Satellite-Connected Internet of Things

Posted by fidest press agency su mercoledì, 27 giugno 2018

Cog, maker of the world’s most secure IoT security solutions, today announced that Fleet, an Australian Internet of Things startup, has partnered with the company to advance the security of satellite-connected Internet of Things (IoT) devices. Fleet will deploy Cog’s D4 Secure platform on trial projects around the world. The companies will also co-present as part of the Innovation Review of IoT Sensors on June 28, at the Sensors Expo to be held at McEnery Convention Center in San Jose, California.With its focus on satellite-enabled massive IoT devices, Fleet connects hundreds, thousands or tens of thousands of industrial devices in areas with no cellular or public low-power wide-area network (LPWAN) coverage. Fleet’s solution is especially effective for remote industrial agriculture, maritime logistics, mining and environmental applications.“We were drawn to Cog’s D4 Secure platform because of its ability to use modularity to isolate critical functions on cutting-edge IoT devices like ours,” said Flavia Tata Nardini, CEO of Fleet. “They are the perfect partner to increase device security as we focus on building the technology that will become the digital nervous system for our planet.”The companies will install Cog’s D4 Secure platform to provide proactive kernel protection, radio isolation for satellite communications, and a VPN tunnel to ensure secure data transport for Fleet devices. As a final step, Cog will isolate other sensors so they only draw battery power when a specific event is executed.“Fleet has taken satellite IoT and made it incredibly simple for organizations around the world,” said Carl Nerup, Co-Founder and Chief Marketing Officer for Cog. “At Cog, we recognize that any remote device connected by satellite needs an extra layer of security. Our focus is on optimizing the devices for performance and reduced latency, while adding defense-grade security. It is a distinct honor that Fleet selected Cog as their security partner.”

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Online School Seniors to Accept Diplomas in Virtual Graduation Ceremony

Posted by fidest press agency su mercoledì, 27 giugno 2018

K12 International Academy (iCademy), an accredited online private school open to students in kindergarten through 12th grade worldwide, will honor the Class of 2018 on Thursday, June 28. Unlike traditional graduation ceremonies for brick-and-mortar schools, this innovative ceremony will happen online starting at 12 p.m. EDT.“At K12 International Academy, we believe a child’s ability to get a great education should not be limited by geography, and our diverse population of students from across the globe is proof,” said head of school Leslie Smith. “This graduating class has benefitted from a combination of innovative technology, excellent teachers and a rigorous curriculum, which has set them up for success in the next chapter of their lives.” The K12 International Academy student population represents every state in the U.S. and over 90 countries around the globe. Most students take a college preparatory curriculum over a four-year period and students graduate with a U.S. diploma. Eligible seniors may also enroll in a dual enrollment program to obtain college credits.This year, 135 students from 31 states and 19 countries will graduate from iCademy. The Class of 2018 reports it has been offered more than $2 million in college scholarships collectively. Graduates report that they have been accepted to prestigious colleges and universities across the country, including Arizona State University, Baylor University, California State University-Northridge, Emory-Riddle Aeronautical University, George Washington University, Hofstra University, James Madison University, Stanford University, Syracuse University, University of Alabama, University of Colorado, University of Florida, University of North Carolina, University of Texas and Virginia Tech. Some graduates also plan to attend schools overseas, including Australia National University, London School of Economics, Instituto de Empresa University, the Hague University of Applied Science, University of Sheffield, University of St. Andrews and Vrije Universiteit.Paul-Antoine Seitz and Olivia Archer are co-valedictorians. Seitz, who graduated high school early, has lived across the globe and plans to attend McGill University in Montreal. Archer will attend Elon University on a full-ride tennis scholarship. The Class of 2018 salutatorian is Laura Vazquez del Mercado. The native of Bogota, Colombia, will attend IE University in Madrid, where she will double major in business administration and law.All three students will address their classmates, along with guest speaker Josephine Chuah, a 2012 iCademy alumna who currently lives in Malaysia, where she works for a company that teaches foreign language through live online lessons.

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Hasbro to Webcast Second Quarter 2018 Earnings Conference Call

Posted by fidest press agency su mercoledì, 27 giugno 2018

Hasbro, Inc. (NASDAQ: HAS) today announced that it will webcast its second quarter 2018 earnings conference call on Monday, July 23, 2018 at 8:30 a.m. Eastern Time, following the release of Hasbro’s financial results. Certain financial and statistical information included in the webcast, such as information required by Regulation G, will be available at the time of the webcast in the “Press Releases” section of Hasbro’s website at http://www.hasbro.com, under “Corporate – Investors.”The webcast and the accompanying presentation slides will be available to investors and the media on Hasbro’s Investor Relations home page at http://investor.hasbro.com. A replay of the call will be available at the same location approximately two hours following the completion of the event.Hasbro (NASDAQ: HAS) is a global play and entertainment company committed to Creating the World’s Best Play Experiences. From toys and games to television, movies, digital gaming and consumer products, Hasbro offers a variety of ways for audiences to experience its iconic brands, including NERF, MY LITTLE PONY, TRANSFORMERS, PLAY-DOH, MONOPOLY, BABY ALIVE and MAGIC: THE GATHERING, as well as premier partner brands. Through its entertainment labels, Allspark Pictures and Allspark Animation, the Company is building its brands globally through great storytelling and content on all screens. Hasbro is committed to making the world a better place for children and their families through corporate social responsibility and philanthropy. Hasbro ranked No. 1 on the 2017 100 Best Corporate Citizens list by CR Magazine and has been named one of the World’s Most Ethical Companies® by Ethisphere Institute for the past seven years.

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Iron Bow Technologies Named as a Top 2018 Workplace by The Washington Post

Posted by fidest press agency su mercoledì, 27 giugno 2018

Iron Bow Technologies, an information technology solutions provider to the government, commercial and healthcare markets, is proud to announce it has been named a “2018 Top Workplace” by The Washington Post.“It is truly an honor to be recognized by The Washington Post for our unique culture and serves as validation that The Iron Bow Way is making a difference with customers, partners and the Iron Bow team,” said Rene LaVigne, President and CEO of Iron Bow Technologies. “We are fortunate to achieve continued success and our innovative and forward-thinking philosophies are key contributors to our thriving culture.” “This is our fourth consecutive year being recognized as a DC area top workplace. Our goal is to continue ranking among top workplaces and to provide exceptional service to our clients – all while supporting our colleagues with a healthy and happy work/life balance,” adds Debbie Yassine, Vice President of Human Resources.The annual list is based on employee feedback from a survey conducted by Work Place Dynamics, LLC, an independent research company. Evaluations of employers are based on several factors, including the quality of leadership, pay and benefit practices and work-life balance.

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Octo Telematics Powers First UBI Program in Mexico with Ana Seguros

Posted by fidest press agency su mercoledì, 27 giugno 2018

Octo Telematics, a leading global provider of telematics and data analytics solutions for the auto insurance industry, announced that its customer Ana Seguros, a part of Grupo Valore, has launched Mexico’s first usage-based insurance (UBI) program, Ana Telematics, powered by Octo Telematics. Ana Telematics lets customers save on their auto insurance based on their driving habits and makes Ana Seguros the first Mexican insurance company to implement and integrate telematics technology in its offerings.The use of telematics data for monitoring driver behavior continues to grow in North America, with potential for significant impact on insurance ratings and models, as well as consumer expectations for pricing. The continued evolution of the technology and disruptive risks means the insurance industry must learn to integrate such technology with existing insurance business models, and think about how telematics will connect in the bigger IoT landscape. Octo Telematics and its vast experience offers insurers like Ana Seguros an opportunity to better assess risk and provide a personalized and improved customer experience. The Ana Telematics programs includes UBI, driving behavior scoring, distracted driver monitoring, crash and claims management and location-based services.“We strive to be at the forefront of insurtech innovation in Mexico, and partnering with Octo Telematics is a key component to that successful execution,” said Dr. Rigoberto Mora Jacob, Claims Director, Ana Seguros. “We are the best option to cover the needs of motor vehicle insurance in Mexico, adhering to the highest industry standards, management efficiency, and the innovation of products and services. Octo’s industry experience and vast telematics database compliments our mission and we are excited to rollout this new value-added offering to our policyholders.”Octo Telematics’ vast telematics database and position as the largest and most experienced insurance telematics company enables Ana Seguros to customize insurance premiums, encourage safer driving habits and offer new discounts add additional value for its customers. Octo’s IoT next generation platform enables Ana Seguros to not only track driving habits of policyholders, but also the use and health of their vehicles.“Industry developments such as IoT and the sharing economy are changing the way – and the frequency of how much – cars are driven as well as policyholder expectations and options,” said Nino Tarantino, CEO of Octo North America. “Ana Seguros is leading the insurance industry in Mexico with value-added programs that add substantial policyholder value to increase engagement, loyalty and retention – and thus, the bottom line for shareholders. We love driving the future of connected insurance for our partners like Ana Seguros.”

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Libro: “Fra mani rifiutate” di Pietro Romano

Posted by fidest press agency su mercoledì, 27 giugno 2018

Roma Il giorno 28 giugno, alle ore 19.30, presso Divago-Vini e spiriti, in via del Pigneto 184, verrà presentato “Fra mani rifiutate” di Pietro Romano (collana Z Diretta da Nicola Vacca per i Quaderni del Bardo Edizioni di Stefano Donno). A moderare l’incontro sarà la Dottoressa Serena Brunelli. Questa è la terza tappa del progetto Il Tempo di un caffè – on the road book tour. La poesia è la casa delle parole e il poeta cerca la porta per potere abitare le sue stanze. Fra mani rifiutate è il libro di Pietro Romano, un poeta che scava nelle stanze delle poesia con l’intenzione di stabilire un contatto con le parole. I suoi versi indicano attraversamenti, scorticano la realtà fino a cogliere della sua forma tutta la scarnificazione che è necessaria a stabilire un contatto con l’esistenza. La sua poesia, in questo senso, è coma di varianti infinite che esplorano l’esistenza e i suoi campi minati. Il poeta prende tra le mani la parola e con gli occhi vigili sul mondo, quasi a voler lasciare una testimonianza, si insinua tra le pagine di quel “sentimento dell’esserci”, perché quello che conta nell’insensatezza di tutto è lasciare una traccia. Fra mani rifiutate è il libro di un poeta consapevole dell’importanza delle parole e del fatto che non ci sono parole all’altezza del presente che ci inghiotte. Davanti alle ustioni del mondo il poeta ha il dovere di inventare una lingua che brucia. Pietro Romano nelle sue poesie incendia le parole, chiama lo spavento in cui siamo finiti con il suo nome e non fa sconti al disincanto che ci assedia. (Nicola Vacca)Pietro Romano (Palermo 1994) Appassionato di arte e letteratura, inizia fin dalla tenera età ad abbozzare brevi poesie e racconti. Dopo essersi diplomato al Liceo Classico Vittorio Emanuele II di Palermo, frequenta il corso di Laurea in Lettere della sua città laureandosi con una tesi dal titolo “Le due anime di Giuliana Saladino: fra giornalismo e letteratura”. È autore di una raccolta di poesie, dal titolo “Il sentimento dell’esserci” (Rupe Mutevole, 2015). Suoi scritti compaiono in diverse antologie cartacee e riviste, fra cui Nel nome di Alda (Ursini Edizioni, 2015) e Repertorio di Arte e Poesia (Ursini Edizioni, 2016), In Verbis Lingue Letterature Culture anno VI, n 1, 2016 Ridersela della cultura. Comicità e sovversione delle idee dominanti tra XV e XVIII secolo (Carocci, 2016).iQdB edizioni di Stefano Donno (i Quaderni del Bardo Edizioni di Stefano Donno)

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