Fidest – Agenzia giornalistica/press agency

Quotidiano di informazione – Anno 33 n° 244

Archive for 5 maggio 2019

Polifarma compie 100 anni

Posted by fidest press agency su domenica, 5 maggio 2019

Milano. 170 dipendenti in Italia, il 35% dei quali under-35, sviluppo sul mercato mondiale e una previsione di crescita del 30%, per un fatturato di oltre 55 milioni di euro atteso nel 2019, di cui il 50% destinato a nuovi progetti con un approccio digital oriented: sono i numeri che fotografano la realtà di Polifarma, una delle aziende farmaceutiche più antiche d’Italia, fondata a Roma nel 1919 e da vent’anni sotto la guida della signora Luisa Angelini che ne ha fatto un punto di riferimento nel mercato farmaceutico italiano, grazie a un nuovo modello di business e costanti investimenti a favore dell’innovazione.
Dalla nascita di una piccola azienda locale agli inizi del ‘900, Polifarma è cresciuta puntando sulla qualità e l’eccellenza dei propri prodotti e del capitale umano, uniti a un’informazione scientifica di valore veicolata alla classe medica, che, negli anni, le ha consentito di stringere importanti collaborazioni con multinazionali farmaceutiche per la gestione, il lancio e l’acquisto di nuove molecole.
Il vero ‘cambio di marcia’ di questo percorso di crescita lungo un secolo è avvenuto nel 1999 con l’acquisizione di Polifarma da parte del Gruppo Final, società finanziaria fondata dalla signora Luisa Angelini che, forte dell’esperienza maturata nell’impresa di famiglia, ha dato un nuovo impulso all’organizzazione aziendale, puntando sulle persone che già ne facevano parte e scegliendo di reinvestire la totalità dei profitti generati, nonché supportare l’azienda con ulteriori investimenti su nuovi progetti. Una strategia imprenditoriale che ancora oggi anima la proprietà e il top management, volta a promuovere la crescita del valore dell’azienda e dei posti di lavoro.Un’altra tappa fondamentale della storia di Polifarma si è aperta nel 2008: l’azienda, a seguito di un momento di crisi – con conseguente perdita di oltre il 40% del fatturato – dovuto a scadenze brevettuali e alla perdita di prodotti in licenza in area cardiovascolare, ha avviato un processo di change management che ha coinvolto le risorse umane, l’organizzazione e il modello di business, a cui si è aggiunto un forte investimento in innovazione in ambito digitale. Un cambiamento costruito intorno alle persone e fondato sulla diffusione, a tutti i livelli, di una cultura dell’innovazione come opportunità per gestire la complessità del mercato e di un rinnovato portfolio prodotti, esteso alle aree gastroenterologica, del sistema nervoso centrale e oftalmologica (oggi area di punta, che assorbe il 39% del fatturato totale).
Nei suoi cento anni di vita, Polifarma ha saputo coniugare il modello italiano dell’azienda di medie dimensioni con quello di un’impresa moderna che ha fatto dell’innovazione, della continuità manageriale e della centralità delle persone i fattori chiave per crescere e rimanere protagonisti in un settore altamente competitivo e in costante evoluzione. Dal 2014 ad oggi, in uno scenario generale fortemente cambiato, il fatturato di Polifarma è cresciuto del 41,8%, passando dai 29,6 milioni del 2014 ai 42 milioni nel 2018, con previsioni di ulteriore crescita per il 2019 (+30% rispetto al 2018).Altro fattore di successo, in controtendenza rispetto ad un settore farmaceutico ancora indietro in tema di digitalizzazione, è stata la creazione di un ecosistema digitale integrato a tutte le funzioni e i progetti aziendali, sviluppato con investimento iniziale molto rilevante in tre anni.

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Venezuela: sen. Rojc, migliaia di italiani “intrappolati”

Posted by fidest press agency su domenica, 5 maggio 2019

“La drammatica situazione politico-militare in Venezuela sta tenendo ‘intrappolati’ anche migliaia di italiani che vorrebbero lasciare il paese ma che non possono farlo a causa dell’impossibilità di rinnovare il passaporto, perché i nostri consolati hanno scarsità di energia elettrica”. E’ l’allarme lanciato dalla senatrice del Pd Tatjana Rojc, che ha presentato al ministro degli Esteri Moavero Milanesi una interrogazione urgente chiedendo al Governo “un intervento immediato a favore della comunità italiana in Venezuela, che conta oltre 200mila persone”.
“La nostra ambasciata e i nostri consolati in Venezuela – scrive Rojc a Moavero – sono bloccati a causa dall’assenza di energia elettrica che viene erogata per 6 ore al giorno e non tutti i giorni. Si tratta di una vera e propria emergenza in quanto risulta impossibile rinnovare un passaporto e siccome – spiega Rojc – il rinnovo può essere fatto solo attraverso i consolati esteri e non mediante quelli italiani, la situazione è a dir poco esplosiva”.
Da qui la richiesta della parlamentare dem al ministro degli Esteri di un “intervento immediato da parte del Governo italiano per agevolare i nostri connazionali in Venezuela, tenuto conto che recentemente a Maracaibo – ricorda Rojc – oltre 500 italiani hanno formalizzato una forte protesta, come riportato anche da “La Voce d’Italia”.
“Siamo inoltre in presenza – continua la parlamentare del Pd – di una difficile reperibilità dei farmaci e dunque chiedo cosa il nostro governo intenda fare per aiutare gli italiani che volessero lasciare subito il Venezuela, consentendo di rinnovare da subito i passaporti, qualora la situazione precipitasse”.
Rojc chiede anche “se il governo intenda intervenire affinché le nostre comunità possano disporre di appositi generatori di corrente, tenuto conto che in Venezuela d’estate si raggiungono i 40 gradi di temperatura e i condizionatori non funzionano per l’assenza di elettricità”.

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AM Best Affirms Credit Ratings of National Reinsurance Corporation of the Philippines

Posted by fidest press agency su domenica, 5 maggio 2019

AM Best has affirmed the Financial Strength Rating of B++ (Good) and the Long-Term Issuer Credit Rating of “bbb” of National Reinsurance Corporation of the Philippines (Nat Re) (Philippines). The outlook of these Credit Ratings (ratings) is negative. The ratings reflect Nat Re’s balance sheet strength, which AM Best categorizes as strong, as well as its adequate operating performance, neutral business profile and appropriate enterprise risk management.Nat Re’s balance sheet strength is underpinned by its risk-adjusted capitalization, as measured by Best’s Capital Adequacy Ratio (BCAR), which is expected to remain at the strongest level over the medium term. Capital adequacy is supported by the company’s low underwriting leverage. However, this is offset by Nat Re’s sizable holding of local equity investments, with fair value movements having driven a level of volatility in capital and surplus over recent years. The company is expected, however, to reduce its exposure to this higher risk asset class during 2019, and increase its allocation toward cash, deposits and fixed income instruments. During the past five years, Nat Re’s overall earnings have remained positive, driven by a steady stream of investment income, which has helped offset unfavorable technical results. Since 2013, Nat Re has undertaken a series of portfolio remediation exercises aimed at improving underwriting profitability and reducing volatility. In particular, the company has reduced its exposure to underperforming property lines of business and increased its business allocation to life reinsurance, which is currently profitable. While the company’s combined ratio has improved over recent years, it remained loss making in 2018. The negative outlooks for Nat Re’s ratings reflect the continued pressure and volatility that AM Best expects underwriting performance to place on overall earnings over the near term.
Nat Re is the only domestic reinsurer in the Philippines, and benefits from strong relationships with local cedants and access to business through mandatory local cessions. In addition, the company underwrites a sizable portfolio of overseas business, which aids with geographic and line-of-business diversification. Offsetting business profile factors include the company’s moderate cedant concentration, and the ongoing challenging market conditions and competition from larger international reinsurers.

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Seabury Capital’s Maritime Subsidiary Advises Connecticut Port Authority on State Pier’s Expansion

Posted by fidest press agency su domenica, 5 maggio 2019

Seabury Maritime LLC (“Seabury Maritime”), the global maritime and transportation investment & merchant banking and industry advisory firm and an affiliate of Seabury Capital Group LLC (“Seabury Capital”), announced today that the company acted as the transaction advisors to the Connecticut Port Authority (“CPA”) in a public and private investment to redevelop State Pier into a world-class 21st century port facility, expanding its economic potential while capturing emerging opportunities.The estimated $93 million investment will transform State Pier into a world-class state of the art facility, while creating a platform for heavy lift cargo, such as offshore wind components, to utilize Connecticut’s ports.“This is an exciting opportunity for the State,” said Patrick Bird, Managing Director – Global Head of Advisory of Seabury Maritime. “By partnering with the offshore wind industry, this new redevelopment plan will put State Pier on a growth trajectory, making it a big step towards realizing the port’s economic expansion and fulfilling the strategic objectives of the Port Authority.” The two-phased redevelopment plan involves a three-year planned upgrade of the facility’s infrastructure to meet the heavy lift requirements of Bay State Wind’s offshore wind components. Following successful project completion, Bay State Wind will enter into a 10-year lease agreement granting the joint venture between Eversource and Ørsted exclusive use of State Pier for assembly and deployment of offshore wind components. Gateway Terminals, originally of New Haven, CT, signed a long-term concession agreement in January and will act as the new terminal operator.

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Delivery Biz Pro Services New Zealand’s Eketahuna Country Meats

Posted by fidest press agency su domenica, 5 maggio 2019

Delivery Biz Pro (DBP), a unit of GetSwift, Inc. (GetSwift) and global farm-to-table SaaS provider, which offers software to facilitate delivery between farms and providers of fresh produce to homes and businesses, is pleased to welcome New Zealand’s Eketahuna Country Meats to its platform.Eketahuna Country Meats is a family-owned and operated online service specializing in sustainably-raised beef, lamb, and pork, along with fresh glass-bottled milk, to customers in New Zealand. This is the latest in a series of relationships DBP has developed recently and underscores its flexibility to help companies across the globe.While Eketahuna previously offered milk at some Wellington markets, DBP is helping the company bring back the tradition of fresh, full-cream milk delivered straight to home doorsteps in glass bottles.Judd Payne, Vice President at GetSwift, added “It’s great to see a company like Eketahuna joining the local farm-to-table movement. Their commitment to quality and transparency in producing meats and dairy is absolutely refreshing…the words ‘commercialized’ and ‘processed’ are far removed from this farm.” Eketahuna prides itself in offering meats and milk from animals raised entirely free of hormones, antibiotics, GMOs and farmed with minimal pesticide use. The company started eight years ago, initially selling beef and lamb from its own 300-acre farm and has since made partnerships with a small number of family farms.

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Governor Kemp Signs Historic SB 157 at Community Bankers Association of Georgia Headquarters

Posted by fidest press agency su domenica, 5 maggio 2019

Governor Brian P. Kemp signed SB 157 into law at the Community Bankers Association of Georgia (CBA) headquarters today before a group of community bankers from across the state.
SB 157 allows community banks, many of which are located in rural Georgia, to accept local government’s funds and allows these banks in turn to reinvest and loan monies back into their own communities and spur economic activity. Increased lending will spur business growth, jobs, and boost statewide economic activity. SB 157 was unanimously passed by the legislature during the 2019 legislative session.CBA’s President and Chief Executive Officer John McNair stated, “We greatly appreciate Senator John Kennedy (R), Macon and Representative Dale Washburn (R), Macon, for guiding the bill through this legislative process. We are also thankful for our partnerships with National Federation of Independent Businesses (NFIB), the Georgia Municipal Association (GMA), and the Association of County Commissioners (ACCG) in making this bill a possibility. SB 157 will change people’s lives, and all of us at CBA are proud, honored and humbled to have had the opportunity to impact Georgia’s community banking industry in this most positive manner!” Community banks are the primary providers of credit and banking services throughout the state and play a vital role in helping the Kemp administration fulfill its objective of further developing and growing small businesses in Georgia. This bill will allow community banks to compete with large, mostly out-of-state banks, for local municipal accounts and deposits. Georgia’s community banks will be able to dramatically increase lending in their local markets thereby helping small businesses start and grow, funding homeownership as well as a variety of agriculture and consumer loans.Governor Brian P. Kemp stated, “By supporting small businesses and local entrepreneurs, this legislation is another positive step toward a new day in rural Georgia. I thank the General Assembly and the Community Bankers Association for their hard work on this important issue and their efforts to bring greater prosperity to all corners of our state.”
“I am pleased and honored to have sponsored this legislation,” remarked Senator John F. Kennedy, (R), Macon. “This is a ‘win-win’ for all of Georgia, but especially rural Georgia, the local governments of Georgia and our banking community who serve our businesses and help so much with much needed economic development.”The ceremony began with remarks by CBA Chairman Mr. Tim Jones (Citizens Community Bank, Hahira), Senator John F. Kennedy (bill sponsor), CBA President and CEO Mr. John McNair and CBA Director of Legislative Affairs Mrs. Lori Godfrey. The Governor offered remarks, signed SB 157 and visited with community bankers afterwards. CBA hosted a brief reception following the ceremony.

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Phase III CAPTAIN Study of Trelegy Ellipta in Patients with Asthma Meets Primary Endpoint

Posted by fidest press agency su domenica, 5 maggio 2019

GlaxoSmithKline plc (LSE/NYSE: GSK) and Innoviva, Inc. (NASDAQ: INVA) today announced headline results from the pivotal phase III CAPTAIN study of once-daily single inhaler triple therapy Trelegy Ellipta (fluticasone furoate/umeclidinium/vilanterol: FF/UMEC/VI) compared to Relvar/Breo Ellipta (FF/VI), in the treatment of patients living with uncontrolled asthma.The study met its primary endpoint, demonstrating a statistically significant 110mL improvement in lung function (measured by change from baseline in trough FEV1 at 24 weeks of treatment) for FF/UMEC/VI 100/62.5/25mcg (p<0.001, 95% CI: 66-153 mL) compared with Relvar/Breo 100/25mcg and a statistically significant 92mL improvement in trough FEV1 for FF/UMEC/VI 200/62.5/25mcg versus Relvar/Breo 200/25mcg (p<0.001, 95% CI: 49-135 mL).The key secondary endpoint was annualised rate of moderate/severe exacerbations for FF/UMEC/VI (100/62.5/25 and 200/62.5/25) versus Relvar/Breo (100/25 and 200/25) and demonstrated a 13% (95% CI: -5.2 to 28.1) reduction in exacerbations, however this was not statistically significant. Therefore, all subsequent analyses were considered descriptive.
Dr. Hal Barron, Chief Scientific Officer and President, R&D, GSK, said: “We believe a once-daily single inhaler triple therapy that improves lung function is an advance for patients with uncontrolled asthma since this option is not currently available. We plan to submit these data for regulatory review after the full dataset is available.”CAPTAIN was also designed to investigate two further doses of FF/UMEC/VI (100/31.25/25 and 200/31.25/25 mcg) compared to Relvar/Breo (100/25 and 200/25). There were increases in trough FEV1 of a similar magnitude to those of FF/UMEC/VI 100/62.5/25 and 200/62.5/25, with no difference in exacerbation rates.The safety profile of FF/UMEC/VI was consistent with the known profile of the individual components and their combinations. Adverse event rates were similar across all six study arms with the most common adverse events being reported as nasopharyngitis (13-15%), headache (5-9%), upper respiratory tract infection (3-6%) and bronchitis (3-5%).Dr. Paul Meunier, Vice President of Respiratory Medicine at Innoviva noted that: “The CAPTAIN study has shown that triple therapy in a single inhaler provides a potential new treatment option for asthma management in patients uncontrolled on ICS/LABA.”
Full results from CAPTAIN will be submitted for future presentation at upcoming scientific meetings and in peer-reviewed publications.

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18th Annual Comcast Cares Day

Posted by fidest press agency su domenica, 5 maggio 2019

More than 5,000 Comcast NBCUniversal employees, their families, friends and community partners will make change happen as they volunteer to improve California schools, homeless shelters and community organizations as part of the 18th annual Comcast Cares Day. This year, volunteers can sign up for more than 70 Comcast Cares Day projects taking place between April 1 and May 13, giving Comcast employees the opportunity to volunteer at projects throughout Northern California.In addition, Comcast Cares Day volunteers will make more than 10,000 paracord survival bracelets and write letters of gratitude which will be sent in care packages to members of the United States Military as part of an initiative called “Operation Gratitude.” Each survival bracelet is hand woven by a volunteer using cords that can hold 550 pounds. It can be deployed in five seconds and reconstructed in one minute. Each bracelet will include a personalized message of support for U.S. troops deployed overseas.Comcast Cares Day is more than just a day – it is an illustration of the spirit of volunteerism that Comcast employees bring to life each and every day. From using technology to create positive change, such as teaching digital literacy skills, to mentoring youth, to stocking food banks, to beautifying parks, Comcast NBCUniversal employees volunteer during this celebration and throughout the year to make a lasting impact. To date, more than 1 million Comcast Cares Day volunteers have contributed over 6 million service hours to improve local communities at more than 10,000 projects. This year, the Company expects more than 100,000 volunteers from Comcast, NBCUniversal, and for the first time Sky, to participate in projects across the country and around the world.

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Awareness of Fatty Liver Disease Remains Low Among Most At-Risk Patients

Posted by fidest press agency su domenica, 5 maggio 2019

The results of a new survey released last week at the 3rd Annual NASH (nonalcoholic steatohepatitis) Summit in Boston show that even among patients most at-risk for the fatty liver disease, awareness of the condition remains low.Global clinical trial enrollment company Continuum Clinical, which conducted the survey, found that among Americans with co-morbidities most associated with NASH—including type 2 diabetes, obesity, and hypertension—only 6% have ever heard of NASH. In a previous survey Continuum conducted of 1,000 Americans, unaided awareness of NASH was only 2%.”Low public awareness of NASH and fatty liver disease is a barrier to clinical trial enrollment,” said Cathleen Dohrn, Ph.D., Continuum Clinical’s Senior Scientific Director who presented the findings at the Summit. “NASH clinical trial sponsors need thousands of patients in order to find the first treatment for this condition, which will necessitate increased awareness and diagnosis of NASH.”According to the National Institute of Diabetes and Digestive and Kidney Diseases, NASH is an advanced form of nonalcoholic fatty liver disease (NAFLD), a condition in which excess fat is stored in your liver and is not caused by heavy alcohol use. NAFLD is one of the most common causes of liver disease in the United States, and a precursor to NASH. Experts estimate that about 20 percent of people with NAFLD have NASH.Continuum also found that 48% of at-risk Hispanic/Latino respondents were most concerned about liver disease versus 32% of the total population surveyed. In addition, Hispanic/Latino respondents were more significantly more interested in learning about a hypothetical NASH clinical research study (62% versus 49% of the total population).”NASH disproportionately affects the Hispanic/Latino population, so having confirmation that this cohort is interested in clinical research signals to us that a special effort must be made to ensure clinical trial enrollment is inclusive,” Dohrn said.
To help explore strategies on how pharmaceutical companies can tackle this patient enrollment challenge, on May 22 Continuum Clinical will host a webinar on overcoming NASH clinical trial challenges with Wayne Eskridge, CEO of the Fatty Liver Foundation, and Qin Ye, MD, MS, associate principal of ZS Associates.

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Keysight Technologies, Calterah Collaborate to Launch New Generation Automotive Radar Chipset

Posted by fidest press agency su domenica, 5 maggio 2019

Keysight Technologies, Inc. (NYSE: KEYS), a leading technology company that helps enterprises, service providers and governments accelerate innovation to connect and secure the world, has joined forces with China’s leading automotive millimeter wave radar chipset design house, Calterah, to support the design, verification, test and launch of a new generation of automotive millimeter wave radar chipset that will drive development of the connected car supply chain.In March 2019 Calterah officially released the ALPS family of chips which integrates high-speed analog-to-digital converters, complete radar signal processing baseband and high-performance CPU core. In the process of design and verification of this chip, Keysight supported Calterah with the company’s E8740A automotive radar signal analysis and generation solution for 77GHz radar signal receiving and transmission characterization, radar target simulation, and testing of the basic radio frequency parameters of the chip. Engineers from both companies worked together to accelerate time to market of the chipsets, while ensuring they deliver the best possible performance.

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