Fidest – Agenzia giornalistica/press agency

Quotidiano di informazione – Anno 31 n° 301

Posts Tagged ‘blood pressure’

University of Chicago Researchers Conduct Study of Unique Device to Lower High Blood Pressure

Posted by fidest press agency su giovedì, 13 giugno 2019

The University of Chicago Medicine’s Comprehensive Hypertension Center is participating in an FDA-approved pivotal trial of a novel catheter-based, non-surgical procedure to treat patients with drug-resistant hypertension. This study, called CALM-2 (Controlling And Lowering blood pressure with MobiusHD®), continues the study of the investigational MobiusHD device which was evaluated in an earlier proof-of-concept CALM-FIM which showed significant reductions in blood pressure through six months.The new, larger, multi-center CALM-2 clinical trial has been designed to assess the safety and effectiveness of this unique device as a possible solution for patients whose blood pressure is not controlled with prescribed medications.The research team at the Comprehensive Hypertension Center, led by world-renowned hypertension expert, professor of medicine and Center Director George Bakris, MD, specializes in the assessment and treatment of hard-to-treat hypertension. This includes the assessment of studies examining innovations in resistant hypertension.Specialized stretch-sensitive nerves called baroreceptors are located in the walls of the carotid arteries and play an essential role in the body’s natural blood pressure regulation. The MobiusHD system is used in the first minimally invasive procedure to utilize the baroreceptor mechanism to address uncontrolled hypertension.
The CALM-2 clinical trial, sponsored by Vascular Dynamics Inc., is targeting up to 300 drug-resistant hypertension patients at select medical centers around the U.S. and in the UK and Europe, including UChicago Medicine.

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On World Stroke Day New ESC Stroke Council Urges Better Blood Pressure Monitoring

Posted by fidest press agency su domenica, 30 ottobre 2016

sophia-antipolisSophia Antipolis The European Society of Cardiology (ESC) and its newly created Council on Stroke says World Stroke Day should be a wake-up call for people everywhere. Each year 6.5 million people die from stroke and another 10 million are permanently disabled.
“The real tragedy is that most of these cases are preventable,” said Professor Petr Widimsky, chairman of the ESC Council on Stroke. “People need to check their blood pressure levels, and if they’re high, to get them lower with diet and exercise or medication. Doctors have a variety of safe and effective treatments. But it all starts by knowing your levels.”Studies show that only 50% of people get their blood pressure checked each year and only 30% maintain a healthy level of 140/90 or less.
The European Society of Cardiology is the preeminent science organization advancing all aspects of cardiovascular medicine. Professor Lina Badimon, ESC Vice President for Scientific Affairs, said the new Council on Stroke should make a meaningful contribution in the fight against this disease. “By working together with other experts -neurologists, vascular surgeons, neurosurgeons, neuroradiologists, epidemiologists and others – the ESC Council on Stroke aims at improving stroke awareness and prevention,” said Prof. Badimon. “The Council is also working to optimise strategies for the acute management of stroke, mapping the current situation in Europe and launching a Pan-European initiative in the field of acute stroke.”

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Obesity trebles in Brazil schoolchildren over 30 years

Posted by fidest press agency su sabato, 24 settembre 2016

fortaleza-brazilFortaleza, Brazil Obesity has trebled in schoolchildren in Brazil over the past 30 years, reveals research presented at the Brazilian Congress of Cardiology. The study in more than 5000 children in Rio de Janeiro found obesity rose from 6% in 1986 to 18% in 2016.  The annual congress of the Brazilian Society of Cardiology (SBC) is held in Fortaleza from 23 to 25 September 2016. Experts from the European Society of Cardiology (ESC) will present a special programme.“Our findings are worrying, given that adults who were obese in childhood and adolescence are the most common victims of early death from cardiovascular diseases such as heart attack and stroke,” said last author Dr Andréa Araújo Brandão, a cardiologist at the State University of Rio de Janeiro, Brazil, and abstract coordinator for the congress.The investigators evaluated the rates of obesity, overweight and high blood pressure in 3897 children aged 10 to 15 years attending schools in Rio de Janeiro in 1986 and 1987. They returned to the same schools 30 years later and conducted the same measurements in 1722 children of the same age.They found that the prevalence of overweight and obesity combined nearly doubled over the 30 year period, from 17% to 32%. There was a greater increase in obesity (6% versus 18%) compared to overweight (11% versus 14%) after 30 years.The prevalence of high blood pressure declined between the two periods (11% versus 8%). In 2016, central obesity was present in 46% of the schoolchildren and 60% did not take part in any physical activity.
“Unhealthy lifestyles are becoming more common in schoolchildren in Brazil, with increased intake of processed food that is high in calories and sugar,” said Dr Brandão. “Meals and snacks are often eaten away from home, physical activity is low and leisure time is often sedentary.” “We found a lower prevalence of blood pressure than 30 years ago which could be because we changed from the auscultatory to the oscilometric method of measurement,” she added. “It is worth noting that more children in 2016 had isolated diastolic hypertension and combined systolic/diastolic hypertension, which carry a poor prognosis.” “The high rates of obesity in children in Brazil today puts them at greater risk of type 2 diabetes, heart disease, low self esteem and even depression,” said Dr Brandão. “There is no doubt that we need to encourage healthier habits among these young people,” she continued. “It is of utmost importance to adopt public policies to regulate food in school canteens and impose restrictions on food advertising. Encouraging physical activity at schools and at home, and the reduction of sedentary leisure time, are also important measures.” Dr Brandão concluded: “Family involvement is critical and fundamental to successfully improving children’s lifestyle habits. Paediatricians are key players in the early diagnosis of excess weight and blood pressure changes. Starting at three years of age, every child should have their blood pressure measured each year.” Professor Fausto Pinto, ESC immediate past-president and course director of the ESC programme in Brazil, said: “Prevention of heart disease starts at a young age.2 Children should be encouraged to be physically active and avoid prolonged periods of sitting. Legislation is needed to restrict marketing of unhealthy foods to children and parents should avoid smoking when children are present.” (Authors: ESC Press Office)

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Caution urged in the use of blood pressure lowering treatment for heart disease patients

Posted by fidest press agency su venerdì, 2 settembre 2016

Rome, Italy – 30 August 2016: Caution has been urged in the use of blood pressure lowering treatment for heart disease patients after a study in more than 22 000 patients with coronary artery disease found that too low blood pressure was associated with worse outcomes. The analysis from the CLARIFY registry is presented today at ESC Congress and published in The Lancet.1-3 Professor Philippe Gabriel Steg, principal investigator of the CLARIFY registry, said: “The optimal blood pressure target in patients with hypertension continues to be debated, especially in those with coronary artery disease (CAD). ESC guidelines recommend lowering blood pressure to values within the range 130–139/80–85 mmHg for patients with CAD to reduce the risk of further cardiovascular events.”4He added: “Some argue ‘the lower, the better’ but there is a concern that patients with CAD may have insufficient blood flow to the heart if their blood pressure is too low.” The current analysis of the CLARIFY registry assessed the relationship between blood pressure (BP) achieved with treatment and cardiovascular outcomes in CAD patients with hypertension.
The study included 22 672 patients with stable CAD who were enrolled between November 2009 and June 2010 from 45 countries into the CLARIFY registry and treated for hypertension. The primary outcome was the composite of cardiovascular death, myocardial infarction, or stroke. Secondary outcomes were each component of the primary outcome, all-cause death, and hospitalisation for heart failure.
Systolic and diastolic BPs before each cardiovascular event were averaged and categorised into 10 mmHg increments. Hazard ratios (HRs) were estimated with multivariable adjusted Cox proportional hazards models, using the 120–129 mmHg systolic BP and 70–79 mmHg diastolic BP subgroups as reference.The investigators found that after a median follow-up of five years, a systolic BP of 140 mmHg or more and a diastolic BP of 80 mmHg or more were each associated with an increased risk of cardiovascular events.Professor Steg said: “These results were expected, and are in line with ESC recommendations to reduce blood pressure below these levels in patients with CAD.” Systolic BP less than 120 mmHg was also associated with increased risk for the primary outcome (adjusted HR 1.56 [95% confidence interval (CI) 1.36–1.81]) and all secondary outcomes except stroke. Likewise, diastolic BP less than 70 mmHg was associated with an increase in the risk of the primary outcome (adjusted HR 1.41 [1.24–1.61] for diastolic BP 60–69 mmHg and 2.01 [1.50–2.70] for less than 60 mmHg) and in all secondary outcomes except stroke.“We found that systolic blood pressure less than 120 mmHg was associated with a 56% greater risk of the composite primary outcome of cardiovascular death, myocardial infarction, or stroke,” said Professor Steg. “Diastolic blood pressure between 60 and 69 mmHg was associated with a 41% increased risk of the primary outcome, with risk rising to two-fold when diastolic blood pressure fell below 60 mmHg.” He added: “This large study of hypertensive CAD patients from routine clinical practice found that systolic BP less than 120 mmHg and diastolic BP less than 70 mmHg are each associated with adverse cardiovascular outcomes, including mortality. The findings support the existence of a J-curve phenomenon, where the initial lowering of BP is beneficial but further lowering is harmful.” Professor Steg concluded: “Our results suggest that the ESC recommendation remains valid and physicians should exercise caution when using BP-lowering treatment in patients with CAD. This should however not detract from our efforts to diagnose and treat hypertension which remains massively underdiagnosed and undertreated worldwide.”

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