Fidest – Agenzia giornalistica/press agency

Quotidiano di informazione – Anno 31 n° 259

Posts Tagged ‘cardiology’

HeartSciences Showcases MyoVista® Wavelet ECG at 2018 European Society of Cardiology Congress

Posted by fidest press agency su venerdì, 24 agosto 2018

HeartSciences, a medical device company developing next generation ECG devices using continuous wavelet transform (CWT) signal processing and artificial intelligence, is proud to announce its participation as an exhibitor at the upcoming 2018 European Society of Cardiology Congress (ESC). The Congress will take place at Messe Munich International in Munich, Germany and will run from August 25 to August 29, 2018. HeartSciences will highlight its MyoVista® Wavelet ECG (wavECG™) Cardiac Testing Device as well as recent clinical study results published in the Journal of the American College of Cardiology (JACC)
HeartSciences is advancing the field of electrocardiography through the application of wavelet signal processing and artificial intelligence to develop next generation ECG technology. Wavelet signal processing is currently used in many different industries as an important tool to provide insights and new valuable data related to spectral analysis of a signal. HeartSciences’ MyoVista wavECG Cardiac Testing Device is a 12-lead resting electrocardiograph utilizing continuous wavelet transform (CWT) based signal processing. Patented informatics focus on energy related information rather than conventional voltage-based information. HeartSciences mission is to enable accurate, affordable screening for the early detection of heart disease.

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Report of interventional cardiology practice presented in first extensive survey

Posted by fidest press agency su giovedì, 24 maggio 2018

Paris, France A report on interventional cardiology practice from an extensive survey is presented at EuroPCR 2018, the annual meeting of the European Association of Percutaneous Cardiovascular Interventions (EAPCI), a branch of the European Society of Cardiology (ESC).1
The EAPCI White Book is the first systematic data collection on the practice of interventional cardiology, a branch of cardiology which delivers catheter-based (percutaneous) treatment of heart diseases – for example inserting stents to open clogged arteries (called percutaneous coronary intervention, or PCI). A wide spectrum of resource allocation and treatment implementation was reported by countries participating in the 2016 survey. Hospitals equipped with catheterisation laboratories (the operating rooms for catheter-based procedures) ranged from less than 2 to more than 5 per million people. Likewise the number of interventional cardiologists ranged from 10 to more than 25 per million people. Clinical evidence supports the performance of percutaneous coronary intervention (PCI) by inserting the catheter via the radial artery in the wrist and using drug-eluting stents where indicated. The survey found that more than half of PCIs were performed via the radial artery and drug-eluting stents were frequently used (more than 3,000 cases per million inhabitants) in most of the participating countries. Yet the survey highlighted a low penetration rate of drug-eluting stents in a few countries, suggesting that there are barriers to implementing this effective treatment. Primary PCI, an urgent first treatment to open clogged arteries (rather than clot-busting drugs) is recommended by ESC guidelines for treatment of patients suffering a heart attack.2 Most countries participating in the survey were delivering at least 500 primary PCIs per million inhabitants, the level promoted by Stent – Save a Life!, the EAPCI’s primary PCI implementation programme. The survey shows that transcatheter aortic valve implantation (TAVI) and other percutaneous structural heart interventions are becoming increasingly popular. However, the implementation of this therapy is not uniform among the participating countries due to different reimbursement policies. The survey covers all aspects of interventional cardiology including organisational models, numbers of procedures, resource allocation, and training. The 16 countries participating in the 2016 survey were Belgium, Denmark, Egypt, France, Germany, Greece, Italy, the Netherlands, Poland, Romania, Slovenia, Spain, Sweden, Switzerland, Turkey, and the UK. Future editions will include more ESC member countries.Professor Emanuele Barbato, lead author, said: “The EAPCI White Book is a valuable resource for monitoring the implementation of guideline recommendations in clinical practice. Healthcare payers and regulatory bodies can use it to compare the allocation of resources to interventional cardiology in Europe. The reported trends in practice will enable industry bodies to target investment to clinical needs.” The data were collected by interventional cardiologists in national cardiac societies and working groups under the leadership of Professor Michael Haude, EAPCI President, in collaboration with the ESC Atlas of Cardiology, a compendium of cardiovascular statistics from the 56 ESC member countries. Professor Panos Vardas, senior author of the Atlas and ESC Past President (2012 – 2016) said: “The EAPCI White Book is an important companion to the ESC Atlas of Cardiology, providing more in-depth information on this rapidly growing domain in cardiology.”

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European Society of Cardiology consensus statement on inflammation in atherosclerosis

Posted by fidest press agency su martedì, 15 maggio 2018

Sophia Antipolis A European Society of Cardiology (ESC) consensus statement on inflammation in atherosclerosis is published today in the European Journal of Preventive Cardiology. Written by the ESC Working Group on Atherosclerosis and Vascular Biology, the document concludes that more evidence is needed before anti-inflammatory drugs can join statins as standard treatment to prevent cardiovascular events in patients with atherosclerosis.The statement was triggered by the results of the Canakinumab Antiinflammatory Thrombosis Outcome Study (CANTOS), which were released at ESC Congress 2017.2 The trial showed that by reducing inflammation, the interleukin (IL)-1β inhibitor canakinumab lowers the risk of another cardiovascular event in patients who had a prior heart attack.The consensus paper outlines the links between high cholesterol and inflammation, and highlights the evidence that is now needed so that lowering both cholesterol and inflammation can become dual targets in the prevention of cardiovascular disease.There are numerous connections between high cholesterol and inflammation. Low-density lipoprotein (LDL) cholesterol in the artery wall triggers inflammation. High cholesterol and inflammation are independently associated with an increased incidence of cardiovascular events. Lipid-lowering medications lower the risk of atherosclerotic cardiovascular events, and also have anti-inflammatory effects. The CANTOS trial then showed that anti-inflammatory drugs reduce the incidence of cardiovascular events.Dr José Tuñón, first author of the statement and a cardiologist at the University Hospital Fundación Jiménez Díaz, Madrid, Spain, said: “We are on the cusp of a new era in cardiovascular disease prevention. The basis of protection against cardiovascular disease will continue to be a healthy lifestyle, including not smoking, being physically active, and eating healthy food. In addition, several drugs such as lipid-lowering medication and antithrombotic therapies have proven to be useful in the prevention of cardiovascular events. With further evidence, anti-inflammatory drugs could become one more tool in the treatment of atherosclerosis.”
CANTOS used a human monoclonal antibody (canakinumab) to suppress inflammation by neutralising IL-1β signalling. The authors of the consensus paper state that studies are needed to test whether tools other than antibodies – interference RNAs, for example – can interfere with inflammation. In addition, research should examine if targeting different inflammatory molecules reduces cardiovascular events.Clinical trials are also needed to extend the findings with anti-inflammatory drugs beyond the patient population enrolled in CANTOS. Patients in the trial had elevated levels of high-sensitivity C-reactive protein (CRP), a marker of inflammation, and the median LDL cholesterol level was 82.4 mg/dL.Dr Tuñón said: “LDL-lowering drugs are effective regardless of CRP levels, so we need to know if the same is true for anti-inflammatory medications. European prevention guidelines recommend lowering LDL cholesterol to less than 70 mg/dL to prevent recurrent cardiovascular events.3 We need a clinical trial in patients who have achieved the LDL cholesterol target of less than 70 mg/d to see if anti-inflammatory drugs can lower their cardiovascular risk even further.”He concluded: “There is a large and strong body of evidence showing that lipid-lowering drugs reduce the risk of cardiovascular disease. Anti-inflammatory drugs will not replace lipid-lowering drugs, but look set to become a complementary therapy in patients with atherosclerosis.”

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Heart health will be promoted by health professionals at EuroPrevent 2018

Posted by fidest press agency su lunedì, 26 marzo 2018

Ljubljana, Slovenia 19 to 21 April 2018. The impact of nutrition and lifestyle on cardiovascular health will be key elements discussed by health professionals during EuroPrevent 2018 in Ljubljana, Slovenia, in April.1 EuroPrevent is the annual congress of the European Association of Preventive Cardiology (EAPC), a branch of the European Society of Cardiology (ESC). This year’s event will be held from 19 to 21 April at Cankarjev dom Culture and Congress Centre in Ljubljana. The full scientific programme is available here.The ESC’s prevention congress brings together more than 1,200 healthcare professionals, scientists and policymakers from over 40 countries to discuss the latest evidence on heart health and how to implement it. The overall theme for the congress this year is ‘Evidence based cardiovascular prevention, a lifelong endeavour.’
From 2009 to 2014, cardiovascular disease accounted for over 3.8 million deaths each year, or 45% of all deaths across ESC member countries, and unhealthy diets are the biggest risk factor at population level. Experts at EuroPrevent 2018 will look at global initiatives to lower salt intake, how to prevent obesity and cardiovascular disease by reducing sugar intake, and the latest evidence on saturated fat. As one of the world’s leading voices on cardiovascular science, the ESC has called for stronger regulations on food, including restrictions on marketing foods that are high in fat, sugar and salt to children. With this year’s EuroPrevent congress held in Slovenia, the country’s Minister of Health, Marija Milojka Kolar Celarc also cited the importance of addressing heart health as a collective responsibility. “We are proud to host such an important gathering, which will provide further scientific evidence that foods high in fat, sugar and salt have a direct impact on cardiovascular disease,” she said, “This knowledge from healthcare professionals needs to inform public policy interventions that have the power to shape the environment within which individuals make choices affecting their health.” The European Union, she noted, is “Looking closely at the nexus of nutrition and health and the potential that food policy can have in providing public health safeguards.”
Over the last 20 years, Slovenia has put in place a variety of CVD prevention measures at national and local levels, which include government policies and public campaigns to improve nutrition and encourage physical activity. Health promotion and education programmes are implemented at public health centres, at the workplace and in schools, among other places, aimed at fostering healthy lifestyles that will help to prevent CVD.As well as looking at foods to avoid, EuroPrevent 2018 will include a session devoted to the role of nutraceuticals, such as red rice yeast, in cardiovascular protection.On other prevention topics, leading experts will explain the relative impact of both genetics and lifestyle on the occurrence of cardiovascular disease and discuss how genetics influence the benefits of lifestyle interventions.Two sessions will explore cardiovascular disease in women, including how women differ from men with regard to genetics, prevention, diagnosis, prognosis, and management.4 From 2009 to 2014 the number of deaths due to cardiovascular disease in ESC member countries was higher in women (2.1 million) than in men (1.7 million). Strategies to improve cardiovascular health in women will be discussed. Key opinion leaders will reveal whether men and women need different types of exercise, as well as how motivation and obstacles to exercise differ between sexes.Sleep as a risk factor for cardiovascular disease will be examined in a dedicated session.5 The most up-to-date evidence will be presented on the risks of not getting enough sleep, sleep apnoea – a common problem in obese people – and how to improve the quality and duration of sleep.There is scientific evidence for the cardiovascular benefits of practices such as tai chi, yoga, and sauna and the latest data will be presented at the congress, along with the pros and cons of using these methods to manage cardiovascular risk factors, including blood pressure.

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Stand up: It could help you lose weight

Posted by fidest press agency su giovedì, 1 febbraio 2018

Sophia Antipolis. You might want to read this on your feet. A new study published today in the European Journal of Preventive Cardiology1 found that standing instead of sitting for six hours a day could prevent weight gain and help people to actually lose weight.Prolonged sitting has been linked to the obeSophia Antipolissity epidemic, cardiovascular disease, and diabetes. Europeans sit for up to seven hours a day, and even physically active people may spend most of the day in a chair. This paper examined whether standing burns more calories than sitting. The researchers analysed results from a total of 46 studies with 1,184 participants in all. Participants, on average, were 33 years old, 60% were men, and the average body mass index and weight were 24 kg/m2 and 65 kg, respectively.The researchers found that standing burned 0.15 kcal per minute more than sitting. By substituting standing for sitting for six hours a day, a 65 kg person would expend an extra 54 kcal a day. Assuming no increase in food intake, that would equate to 2.5 kg in one year and 10 kg in four years.
Senior author Professor Francisco Lopez-Jimenez, Chief of Preventive Cardiology at the Mayo Clinic in Rochester, US, said: “Standing not only burns more calories, the additional muscle activity is linked to lower rates of heart attacks, strokes, and diabetes, so the benefits of standing could go beyond weight control.” The gap in energy expenditure between standing and sitting could be even greater than the study found. Participants were standing still, while in reality people make small movements while standing. “Our results might be an underestimate because when people stand they tend to make spontaneous movements like shifting weight or swaying from one foot to another, taking small steps forward and back. People may even be more likely to walk to the filing cabinet or trash bin,” said Professor Lopez-Jimenez.he authors concluded that replacing standing for sitting could be yet another behaviour change to help reduce the risk of long term weight gain. They suggest more research is needed to see whether such a strategy is effective and practical. Data is also needed, they say, on the long term health implications of standing for extended periods.Professor Lopez-Jimenez said: “It’s important to avoid sitting for hours at a time. Standing is a very good first step – no pun intended – to avoid this mindset of sitting interminably without moving. Who knows, it may also prompt some people to do a little more and take up some mild physical activity, which would be even more beneficial.”

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Four in ten cardiomyopathies – a major cause of sudden death in young people – are genetic

Posted by fidest press agency su giovedì, 25 gennaio 2018

Sophia AntipolisSophia Antipolis, 24 January 2018: Four in ten cardiomyopathies – a major cause of sudden cardiac death and heart failure in young people – are genetic, according to a European Society of Cardiology (ESC) study published today in European Heart Journal.1 Family screening is urgently needed to prevent early death in apparently healthy relatives, the paper says.Cardiomyopathy is where the heart muscle becomes enlarged, thick or rigid. As the condition worsens, the heart becomes weaker and less able to pump blood through the body and maintain a normal electrical rhythm. Around one in 300 people in Europe has a cardiomyopathy.This is the first European registry on cardiomyopathies, and was conducted as part of the EURObservational Research Programme (EORP) of the ESC. The study included 3,208 patients enrolled by 69 centres in 18 countries. Data was collected on patient characteristics and treatments.
“We were surprised to see how frequently the disease is inherited,” said first author Cardiology Professor Philippe Charron of the Pitié-Salpêtrière Hospital in Paris, France. “About 40% of patients had familial disease. As a consequence it is very important to improve screening to detect the disease in the relatives who are apparently healthy.”Two-thirds of relatives in the study were diagnosed through family screening, which includes echocardiography and an electrocardiogram (ECG). In many cases their disease was as severe as in the first family member identified, with the same frequency of symptoms and requirement for an implantable cardioverter defibrillator (ICD) to stop life threatening arrhythmias.The study also suggests that recommendations should be changed so that family screening starts earlier than ten years of age and extends beyond the current threshold of 50 to 60 years. The EORP study found that some relatives were diagnosed much younger than ten while others were older than 70.“The cardiac expression of these genetic diseases starts early in some patients,” said Professor Charron. “In others it is delayed for many decades – longer than previously thought.”Genetic testing was performed in 36% of patients in the study – an increase from ten years ago – but not as good as it should be, the paper said. When a mutation is identified, genetic testing can then be performed in first degree relatives. Those with the mutation should have regular cardiac follow up, including an ECG and echocardiogram, to check for changes to heart muscle and function.“The earlier we identify relatives with the mutation, the better we can manage them and prevent complications including sudden cardiac death,” said Professor Charron.Sudden cardiac deaths from cardiomyopathies are caused by heart rhythm disorders, called arrhythmias. An important part of managing patients with cardiomyopathies is to diagnose arrhythmias early. However, the study found that one in three patients did not receive the necessary diagnostic tests. Professor Charron said: “The frequency of arrhythmias in the study was high. In one cardiomyopathy subtype, 39% of patients had potentially deadly arrhythmias. But diagnostic testing for arrhythmias was suboptimal and patients may be missing out on lifesaving treatment with an ICD or pacemaker.”

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Nearly 25% of chronic ischaemic heart disease patients dead or hospitalised in six months

Posted by fidest press agency su mercoledì, 17 gennaio 2018

Sophia Antipolis, Nearly a quarter of patients with chronic ischaemic cardiovascular disease are dead or hospitalised within six months, reports a European Society of Cardiology (ESC) study published today in the European Journal of Preventive Cardiology. “Coronary artery disease is the leading cause of death worldwide yet some patients appear to get lost in the system after their initial visit to a hospital or outpatient clinic,” said lead author Cardiology Professor Michel Komajda, of the University Pierre and Marie Curie and Pitié-Salpêtrière Hospital in Paris, France.
The Chronic Ischaemic Cardiovascular Disease (CICD) Pilot Registry was designed to learn what happens to these patients in the six months after being seen by a health professional. The observational study was conducted as part of the EURObservational Research Programme (EORP) of the ESC.
The study included 2,420 patients from 100 hospitals and outpatient clinics in ten European countries. Participants had stable coronary disease2 or peripheral artery disease, the most common conditions seen by a cardiologist. Risk factors and treatments were recorded at the start of the study and have been previously reported.3 Treatments and outcomes were recorded at six months.
Follow-up data were available for 2,203 patients, of whom 522 (24%) had died or been rehospitalised during the six months. Factors significantly associated with the risk of dying or being rehospitalised were older age, with a hazard ratio (HR) of 1.17 for every ten years, history of peripheral revascularisation (HR 1.45), chronic kidney disease (HR 1.31) and chronic obstructive pulmonary disease (HR 1.42) (all p<0.05). The majority of the causes of death and rehospitalisation were cardiovascular.Professor Komajda said: “These patients are at high risk of dying or being navigatore coronarierehospitalised in the short-term and should be carefully monitored by physicians. We identified clinical factors which are strongly associated with this high risk which can easily be assessed.”
The rate of prescription of angiotensin converting enzyme inhibitors, beta-blockers (both drugs reduce blood pressure) and aspirin was lower at six months compared to the start of the study (all p<0.02).Professor Komajda said: “In absolute numbers the reductions were modest but they did reach statistical significance. This shows that patients have a better chance of receiving recommended medications while in hospital or directly after an outpatient appointment. Six months later, drugs they should be taking to reduce the risk of death and rehospitalisation are prescribed less frequently.”He added: “It is likely that there is insufficient handover of these patients to a cardiologist or GP and so their prescriptions are not renewed.”While the study did not assess the reasons for the reduction in prescriptions, possible factors include: patients getting tired of taking pills or cannot afford them.Six month rates of death and rehospitalisation were significantly higher in eastern, western and northern European countries compared to those in the south. Given the relatively small number of patients, Professor Komajda said firm conclusions could not be drawn. But he said: “We anticipated that outcomes would be better in Mediterranean countries and this was correct, probably because of the diet and other lifestyle reasons.” Professor Komajda concluded: “The study shows that patients with chronic ischaemic cardiovascular disease have a high risk of poor short-term outcomes. Yet some are not receiving recommended preventive medications which could improve their outlook. More efforts are needed to ensure that these patients continue to be monitored and treated after they leave hospital or an outpatient appointment.”

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Interventional Cardiology Devices: Research and Markets

Posted by fidest press agency su martedì, 19 dicembre 2017

cuoreThe “Interventional Cardiology Devices Market by type (Angioplasty, Catheters, Plaque Modification (Atherectomy, Thrombectomy), Hemodynamic Flow Alteration (Embolic Protection, Total Occlusion), Guidewire, Introducer Sheath) – Global Forecast to 2022” report has been added to Research and Markets’ offering. The interventional cardiology devices market is expected to reach USD 20.85 billion by 2022 from USD 14.52 billion in 2017, at a CAGR of 7.5%.Factors driving the growth of this market include rising geriatric population, improving healthcare infrastructure, and increasing incidence of CVD. On the other hand, the stringent regulatory scenario for these devices and the availability of effective first-line treatments is expected to limit market growth in the coming years.The plaque modification devices market, by type, is categorized into thrombectomy devices and atherectomy devices. The thrombectomy devices segment is estimated to grow at the fastest rate during the forecast period. The increasing demand for technologically advanced thrombectomy devices is a key factor driving the growth of this market.The angioplasty stents market is segmented drug-eluting stents, bare-metal stents, and bioresorbable stents. The bioresorbable stents segment is the fastest-growing segment of the global angioplasty stents market. Technological advancement in stents is driving the growth of this segment.
Geographically, the interventional cardiology devices market is dominated by North America, followed by Europe in 2017. Asia Pacific is estimated to grow at the fastest rate, due to infrastructural development in its healthcare systems, the rising burden of CVD, and increasing healthcare expenditure in APAC countries.

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Anticoagulanti, linee guida Usa su gestione del sanguinamento

Posted by fidest press agency su lunedì, 18 dicembre 2017

male doctor with stethoscope reading medical bookL’American College of Cardiology ha pubblicato su Jacc le linee guida sulla gestione del sanguinamento acuto in pazienti in terapia con anticoagulanti orali (Oac), sia diretti (Doac) sia antagonisti della vitamina K. «L’uso dei DOAC è ormai comune in malattie quali la fibrillazione atriale e il tromboembolismo venoso, e aumenterà in futuro» dice Gordon Tomaselli, professore di medicina alla Johns Hopkins University di Baltimora e coordinatore del comitato di esperti che ha firmato l’articolo. «La valutazione e la gestione del sanguinamento, una possibile complicanza della terapia con anticoagulanti orali, può essere particolarmente difficile nei pazienti che assumono quelli diretti per la mancanza di esami del sangue facilmente disponibili» scrivono gli autori, ricordando che un passo fondamentale per valutare la gravità del sanguinamento è stabilire se: il sanguinamento è in un sito critico; il paziente è emodinamicamente instabile; il sanguinamento comporta un calo di emoglobina uguale o superiore a 2 g/dL o la necessità trasfondere due o più unità di globuli rossi. «Se il sanguinamento non è grave (no a tutte le domande precedenti) e non richiede ricovero o procedure invasive, il DOAC va comunque sospeso» riprende Tomaselli, spiegando che per valutare i livelli di dabigatran sono necessari un test di trombina diluito, un tempo di coagulazione all’ecarina o un test cromogenico con ecarina. L’ecarina è un estratto di veleno di serpente che converte la protrombina in meizotrombina, un enzima simile alla trombina. L’aggiunta del veleno al plasma del paziente determina un tempo di coagulazione che normalmente è di pochi secondi, ma che in presenza di dabigatran si allunga in modo proporzionale alla sua concentrazione. Per valutare invece i livelli di farmaco in chi assume un inibitore del fattore Xa (apixaban, edoxaban e rivaroxaban) serve un test di attività cromogenica anti-Xa, mentre PT e aPTT sono di scarsa utilità. «Il documento include algoritmi decisionali sulla valutazione della severità del sanguinamento, suggerimenti per l’uso dei diversi anticoagulanti, indicazioni sugli antidoti e consigli su quando riprendere la terapia anticoagulante dopo un sanguinamento» concludono gli autori. (fonte doctor33) (foto. anticoagulanti)

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Quando il cuore si ammala per troppa felicità

Posted by fidest press agency su sabato, 14 ottobre 2017

ZurigoZURIGO. Si può morire di crepacuore ma anche per troppa felicità. E’ la conclusione di uno studio commentato da Thomas F. Lüscher, Direttore della Divisione di Cardiologia all’Ospedale Universitario di Zurigo, Svizzera, durante il meeting “Hot topic in cardiology” promosso dalla Fondazione Internazionale Menarini e svoltosi recentemente nella città svizzera.
«E’ da quasi trent’anni che il cardiologo giapponese Keigo Dote ha descritto la sindrome di Takotsubo» esordisce Lüscher. «Si tratta di una condizione acuta che può apparire come un attacco cardiaco, con forte dolore al petto e mancanza di fiato, ma agli esami i medici non trovano ostruzioni nelle arterie del cuore e solo un’angiografia alle coronarie conferma la diagnosi». Cosa succede quindi? Lo spiega Paolo G. Camici, Professore di Cardiologia, Direttore della Scuola di Specializzazione in Malattie Cardiovascolari dell’Università Vita-Salute San Raffaele e Responsabile del Centro per le Malattie del Miocardio dell’Istituto Scientifico Universitario San Raffaele a Milano: «Uno stress emozionale può provocare un’eccessiva stimolazione del sistema nervoso e una quantità troppo elevata di adrenalina. Questo ormone se in eccesso può causare una disfunzione del microcircolo del cuore, un’alterazione del ritmo del cuore, sindrome di Takotsubo e morte improvvisa». Finora i medici ritenevano che gli stress emozionali fossero unicamente negativi: rabbia, frustrazione, paura, un lutto, una separazione. Recenti studi, invece, hanno evidenziato che anche una forte emozione positiva può portare a un arresto cardiaco, anche se i casi sono minori.
Sia che le emozioni siano positive o negative sono quasi esclusivamente le donne, in particolare in menopausa, a essere colpite dalla sindrome di Takotsubo. In caso di emozioni negative, nove casi su dieci riguardano donne, anche se il primo episodio storico riguarda un uomo, atleta e campione dell’Antica Grecia.Diagora di Rodi era era famoso per la formidabile forza fisica e per il talento atletico, che gli permisero di vincere in tutti i quattro giochi panellenici. La sua impresa più famosa fu comunque la vittoria nella gara di pugilato dei giochi olimpici del 464 a.C., a seguito della quale gli fu dedicata la VII olimpica di Pindaro, venne celebrato come un eroe a Rodi e gli venne eretta una statua ad Olimpia. Diagora ebbe tre figli maschi, i quali nello stesso giorno vinsero le olimpiadi, uno nel pugilato, uno nel pancrazio e uno nella lotta. Come racconta Aulo Gellio, al termine delle gare i figli issarono Diagora sulle proprie spalle per portarlo in trionfo, ma la gioia di Diagora per le vittorie dei figli fu tale che dopo aver ricevuto i loro festeggiamenti morì.
Prevalenza assolutamente femminile invece nello studio realizzato da Jelena-Rima Ghadri, dell’Ospedale Universitario di Zurigo, Svizzera, e pubblicato sull’European Heart Journal, rivista della Società europea di cardiologia. Su 485 persone colpite dalla sindrome di Takotsubo osservate, in venti la sindrome era stata provocata da emozioni positive: compleanno, matrimonio di un figlio, diventare nonna, ricevere una festa a sorpresa, vincere al casinò, una visita inattesa da una persona cara. Di queste, diciannove su venti erano donne.
«I sintomi erano simili a quelli riferiti dalle persone con sindrome di Takotsubo provocata da emozioni negative, cioè dolore al petto e mancanza di fiato, e anche il cuore si manifestava agli esami e ai test nello stessa caratteristica forma» commenta Lüscher. «Il nome della sindrome infatti deriva dalla forma che il ventricolo sinistro del cuore assume: l’estremità arrotondata e il collo sottile al termine dalla fase sistolica (contrazione), forma che ricorda la trappola per polpi, lo “tako-tsubo” appunto, usata in Giappone. I medici dovrebbero considerare questo aspetto quando in pronto soccorso arriva una paziente con sintomi di attacco cardiaco dopo una forte emozione: potrebbe non trattarsi di infarto ma di sindrome di Takotsubo. Una diagnosi precoce consente di trattare subito la sindrome con farmaci efficaci e ridurre drasticamente il rischio che questa condizione possa provocare la morte della paziente».

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”Cardiology of Today and Tomorrow: Prepared for the Future”

Posted by fidest press agency su martedì, 19 settembre 2017

san pietroburgoS. Pietroburgo (Russia) Dal 21 al 23 settembre 2017 si svolgerà il simposio internazionale “Cardiology of Today and Tomorrow: Prepared for the Future”. Il meeting riunirà cardiologi di fama internazionale che esporranno i più recenti progressi nella cura delle malattie cardiovascolari. «S. Pietroburgo vanta una lunga tradizione nella clinica e nella ricerca in cardiologia, con una consolidata esperienza nella riduzione della mortalità e della morbilità cardiovascolare» spiega Evgeny Shlyakhto, Direttore del Federal Almazov North-West Medical Research Centre di S. Pietroburgo e presidente del simposio. «I cardiologi russi ed europei condividono una lunga storia di collaborazione scientifica ed accademica, che rappresenta un esempio di approccio innovativo di integrazione delle conoscenze e delle esperienze con il concetto di medicina traslazionale».
Il 21 settembre il simposio per la cerimonia di apertura si svolgerà alla Philarmonia – Nevskiy avenue 30, S. Pietroburgo. Sono previste tre letture da parte di Evgeny Shlyakhto (Russia), Alberto Zanchetti (Italy) ed Edward Lakatta (USA).
Il 22 e 23 settembre il simposio si svolgerà al Federal Almazov North-West Medical Research Centre 2 Akkuratova st., S. Pietroburgo. I temi principali saranno le linee guida cardiovascolari europee, russe e statunitensi, l’ipertensione arteriosa e il danno d’organo, la dislipidemia e altre comorbilità, l’ischemia cardiaca e l’angina stabile, l’insufficienza cardiaca. Il simposio è promosso dalla Fondazione Internazionale Menarini.

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”Cardiology of Today and Tomorrow: Prepared for the Future”

Posted by fidest press agency su venerdì, 15 settembre 2017

san pietroburgoS. Pietroburgo (Russia) Dal 21 al 23 settembre 2017 si svolgerà a S. Pietroburgo il simposio internazionale “Cardiology of Today and Tomorrow: Prepared for the Future”. Il 21 settembre il simposio per la cerimonia di apertura si svolgerà alla Philarmonia – Nevskiy avenue 30, S. Pietroburgo. Sono previste tre letture da parte di Evgeny Shlyakhto (Russia), Alberto Zanchetti (Italy) ed Edward Lakatta (USA). Il 22 e 23 settembre il simposio si svolgerà al Federal Almazov North-West Medical Research Centre 2 Akkuratova st., S. Pietroburgo. Il meeting riunirà cardiologi di fama internazionale che esporranno i più recenti progressi nella cura delle malattie cardiovascolari.
S. Pietroburgo vanta una lunga tradizione nella clinica e nella ricerca in cardiologia, con una consolidata esperienza nella riduzione della mortalità e della morbilità cardiovascolare» spiega Evgeny Shlyakhto, Direttore del Federal Almazov North-West Medical Research Centre di S. Pietroburgo e presidente del simposio. «I cardiologi russi ed europei condividono una lunga storia di collaborazione scientifica ed accademica, che rappresenta un esempio di approccio innovativo di integrazione delle conoscenze e delle esperienze con il concetto di medicina traslazionale».I temi principali saranno le linee guida cardiovascolari europee, russe e statunitensi, l’ipertensione arteriosa e il danno d’organo, la dislipidemia e altre comorbilità, l’ischemia cardiaca e l’angina stabile, l’insufficienza cardiaca. Il simposio è promosso dalla Fondazione Internazionale Menarini.

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Insomnia associated with increased risk of heart attack and stroke

Posted by fidest press agency su domenica, 2 aprile 2017

cardiologiaInsomnia is associated with increased risk of heart attack and stroke, according to research published today in the European Journal of Preventive Cardiology. “Sleep is important for biological recovery and takes around a third of our lifetime, but in modern society more and more people complain of insomnia,” said first author Qiao He, a Master’s degree student at China Medical University, Shenyang, China. “For example, it is reported that approximately one-third of the general population in Germany has suffered from insomnia symptoms.” “Researchers have found associations between insomnia and poor health outcomes,” continued Miss He. “But the links between insomnia and heart disease or stroke have been inconsistent.”The current meta-analysis assessed the association between insomnia symptoms and incidence or death from cardiovascular disease (acute myocardial infarction, coronary heart disease, heart failure), stroke, or a combination of events. Insomnia symptoms included difficulty initiating sleep, difficulty maintaining sleep, early-morning awakening, and non-restorative sleep.The authors analysed 15 prospective cohort studies with a total of 160 867 participants. During a median follow-up of three to 29.6 years, there were 11 702 adverse events.
There were significant associations between difficulty initiating sleep, difficulty maintaining sleep, and non-restorative sleep and the risk of heart disease and stroke, with increased relative risks of 1.27, 1.11, and 1.18, respectively, compared to those not experiencing these insomnia symptoms. There was no association between early-morning awakening and adverse events.Miss He said: “We found that difficulty initiating sleep, difficulty maintaining sleep, or non-restorative sleep were associated with 27%, 11%, and 18% higher risks of cardiovascular and stroke events, respectively.”“The underlying mechanisms for these links are not completely understood,” continued Miss He. “Previous studies have shown that insomnia may change metabolism and endocrine function, increase sympathetic activation, raise blood pressure, and elevate levels of proinflammatory and inflammatory cytokines – all of which are risk factors for cardiovascular disease and stroke.”Women with insomnia symptoms had a slightly higher risk of cardiovascular and stroke events than men, especially for non-restorative sleep, but the difference between sexes did not reach statistical significance.Miss He said: “We cannot conclude that insomnia is more dangerous for women, given the limitations of meta-analyses and the lack of a statistically significant difference between sexes. However, we do know that women are more prone to insomnia because of differences in genetics, sex hormones, stress, and reaction to stress. It may therefore be prudent to pay more attention to women’s sleep health.”Miss He concluded: “Sleep disorders are common in the general population and sleep health should be included in clinical risk assessment. Health education is needed to increase public awareness of insomnia symptoms and the potential risks, so that people with sleep problems are encouraged to seek help.”

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Congresso internazionale dal titolo “Highlights in Cardiology”

Posted by fidest press agency su mercoledì, 25 gennaio 2017

navigatore coronarieRoma mercoledì 1 a venerdì 3 febbraio Aula Magna dell’Università degli Studi “La Sapienza” Piazzale Aldo Moro 5 congresso internazionale dal titolo “Highlights in Cardiology”. La prevenzione degli eventi cardiovascolari, soprattutto tra i giovani, aprirà il congresso internazionale. Durante la prima giornata del congresso, infatti, esperti italiani e internazionali parleranno di rischio cardiovascolare nei bambini, morte improvvisa cardiaca negli atleti, utilità dei test sotto sforzo, elettrocardiogramma negli adolescenti. Seguiranno sessioni su differenza di genere e malattie cardiovascolari, arteriosclerosi e ischemia cardiaca, sindrome coronarica acuta e nuovi trattamenti, insufficienza cardiaca e cellule staminali. Il congresso è promosso dalla Fondazione Internazionale Menarini ed è presieduto da Francesco Fedele, Direttore del DAI (Dipartimento Assistenziale Integrato) Malattie Cardiovascolari e Respiratorie, Policlinico Umberto I Roma, e Direttore della Sezione di Cardiologia al Dipartimento Scienze Cardiovascolari, Respiratorie, Nefrologiche e Geriatriche, “Sapienza” Università di Roma.

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Europe’s largest medical congress returns to Paris in 2019

Posted by fidest press agency su mercoledì, 19 ottobre 2016

Paris-antenne-vue-eiffel-tourParis. The European Society of Cardiology (ESC) is proud to announce that its annual congress will be held in Paris at the end of August 2019. The ESC Congress is the world’s premier cardiovascular congress, attracting more than 30,000 healthcare professionals from more than 140 countries during a five-day scientific programme.“We are delighted to be returning to Paris, a destination which contributed to one of the greatest successes of the ESC,” said Chief Executive Officer of the ESC, Isabel Bardinet. “The ESC Congress 2011 that was held in ‘The City of Light’ will be remembered as one of the most productive and well attended ESC events. We hope that this future edition will encounter even greater success in this very attractive capital.”Bernard Jomier, Deputy Mayor of Paris for Health, Disability and relations with the APHP, welcomed this good news for Paris: “After the success of the 2011 edition, Paris is very honoured to once again host the annual congress of the ESC. It is an excellent opportunity to increase the efforts undertaken by the City of Paris for the prevention of cardiovascular disease risks.” This enthusiasm is also shared by Jean-François Martins, Deputy Mayor for Sport and Tourism, who added: “Paris will assure the best conditions to make this major event a success. Once again, Paris proves its capacity to host such world-class events and is going to intensify its work to attract more congresses in the years to come.” Pierre Schapira, Chairman of the Paris Convention and Visitors Bureau, praises: “the daily work carried out by the Convention Bureau teams to increase the attractiveness of the destination, offering help and advice to planners of major events in the capital; work which has been crowned today with this good news.”
Michel Dessolain, CEO of Viparis, is delighted to host the ESC Congress at Paris Convention Centre: “We are proud to contribute to the international appeal of Paris. Paris Convention Centre will provide an optimal setting for major events such as this one. This represents a real vote of confidence for the future Convention Centre of the Parc des Expositions de la Porte de Versailles, which will be the biggest in Europe.”
The Paris Convention Bureau encourages and supports professional associations that wish to propose Paris as a host destination and was proud to count more than 1,000 congresses in 2015. It works alongside Parisian professionals to make the destination even more appealing to associations. More information on its dedicated website: http://www.convention.parisinfo.com

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Pope Francis at ESC Congress 2016

Posted by fidest press agency su giovedì, 1 settembre 2016

pope francisRome. His Holiness Pope Francis honoured the European Society of Cardiology (ESC) with an historic visit to ESC Congress 2016, the world’s largest scientific summit on cardiovascular medicine. “You look after the heart,” His Holiness told the cardiologists. “How much symbolism is enshrined in this word! How many hopes are contained in this human organ! In your hands you hold the beating core of the human body, and as such your responsibility is very great!”Pope Francis added: “The Magisterium of the Church has always affirmed the importance of scientific research for human life and health. The Church not only accompanies you along this demanding path, but also promotes your cause and wishes to support you.”ESC President, Professor Fausto Pinto, in introducing the Pontiff, said: “The European Society of Cardiology, like the Vatican, is committed to alleviating suffering and promoting healthy lifestyles. Both share a common purpose of delivering care to those in need and helping people live more productive lives.” The European Society of Cardiology brings together healthcare professionals from more than 150 countries to push the boundaries of cardiovascular medicine. ESC Congress, held annually at the end of August, presents more than 6,000 scientific abstracts, identifying the latest discoveries and breakthroughs in the field of cardiology. This year’s congress attracted a record 33,000 cardiology professionals.“There is so much more that could be done, that must be done,” Professor Pinto said to Pope Francis. “In Europe alone, 1.4 million people under the age of 75 die prematurely each year from heart attacks and strokes because, in many cases, they are not getting the timely and effective healthcare they need. “Governments, public health systems, clinics, hospitals, universities, we must all recognise the urgency of this public health crisis. And a crisis is exactly what it is, and how it should be seen.”

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Invasive and Interventional Cardiology, Cardiovascular Surgery

Posted by fidest press agency su lunedì, 29 agosto 2016

cardiology congress-2016Rome, Italy The addition of intravenous (IV) N-acetylcysteine (NAC) to IV glyceryl trinitrate (GTN) significantly reduced infarct size by approximately one third in patients undergoing percutaneous coronary intervention (PCI) after ST-segment elevation acute myocardial infarction (STEMI), according to Hot Line research reported here.“Timely and effective myocardial reperfusion by PCI is the treatment of choice for limiting myocardial infarct size and improving clinical outcomes in patients presenting with STEMI. However, additional pharmacological interventions may help to reduce infarct size further,” noted Sivabaskari Pasupathy, PhD candidate, from the University of Adelaide, in Adelaide, Australia, who presented the findings at ESC Congress 2016.“Any intervention that actually reduces myocardial infarct size by approximately a third might reasonably be expected to substantially improve long-term outcomes.”NACIAM (N-AcetylCysteine In Acute Myocardial infarction), a placebo-controlled, double-blind trial, included 112 STEMI patients (mean age 64 years) from 3 Australian hospitals.All patients underwent emergency PCI and also received low dose intravenous GTN. They were randomized pre-PCI to receive either high dose (15 grams/24 hours) NAC or an identical placebo, both delivered intravenously over 48 adelaide australia1hours, “with the hypothesis that NAC might reduce infarct size, either by potentiating the effects of GTN or via ‘scavenging’ of reactive oxygen species,” said Dr. Pasupathy. Cardiac magnetic resonance (CMR) imaging performed within one week (early) and again 3 months post MI (late) showed that patients who received NAC had reductions in infarct size of 33% and 50% respectively compared to placebo (p=0.02 for both).There was a similar but not significant trend towards reduction in creatine kinase release.Additionally, myocardial salvage, measured at one week, was approximately doubled in patients who received NAC (60% vs 27%, p<0.001), and there was also evidence of accelerated tissue reperfusion and hypochlorous acid “scavenging” in these patients.Over 2 years of follow-up, the combination of cardiac readmissions and deaths was less frequent in NAC-treated (3 vs 16 patients, P<0.01).Safety endpoints including hypotension, bleeding, and contrast-induced nephropathy were similar in both groups.“Intravenous NAC administration was associated with more rapid chest pain resolution, improved myocardial salvage, a favourable in-hospital safety profile, sustained infarct size reduction at 3 months post-STEMI, and promising clinical outcomes at 2 years,” concluded Dr. Pasupathy. “While the results of this study are encouraging, we would prefer to regard NACIAM as the precursor of a follow-up study, sized for clinical end-points,” she noted.

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20 cent school intervention stops unhealthy weight gain in children

Posted by fidest press agency su sabato, 27 agosto 2016

cardiology congress-2016Rome, Italy 27 Aug 2016 Fiera di Roma (Ingresso Nord, Via Portuense 1645/1647) A school intervention costing less than 20 cents per child has stopped unhealthy weight gain. The randomised study is presented at ESC Congress 2016 today by Ms Daniela Schneid Schuh, a nutritionist at the Institute of Cardiology of Rio Grande do Sul in Porto Alegre, Brazil.1 “Obesity has reached a plateau in developed countries but continues to rise in many developing countries, such as Brazil,” said Ms Schneid Schuh. “Thus, it is necessary to develop low-cost methods to prevent people become overweight, starting in childhood.”Healthy School, Happy School was a randomised controlled trial designed to test the effectiveness of an intervention stop obesity in children. It was conducted in Feliz, Brazil.“Feliz is the Portuguese word for ‘Happy’, and the study name pays tribute to this small but very special town in South Brazil,” said Ms Schneid Schuh. “Mainly influenced by German immigration, Feliz has one of the highest human development indexes in the country.2 But health problems such as obesity, sedentarism, hypertension and other chronic diseases are aggravated by rising urbanisation and changing eating habits.”The research group in paediatric preventive cardiology in Porto Alegre recruited four public schools in Feliz with students of both genders, aged between five and 16 years. Schools were randomly assigned to one of two groups for nine months: the intervention group (two schools with 73 children), which focused on lifestyle changes at school and at home, or the control group (two schools with 140 riochildren), which only received the usual recommendations from the regular school curriculum. The interventions in the study were delivered by nutritionists in the Research Group on Cardiovascular Prevention in Childhood and Adolescence (PREVINA), nutrition graduate students, and psychologists and nurses employed by Feliz City Hall.Intervention activities occurred monthly in the schools’ multimedia room or sports court, with seminars and workshops about physical activities, healthy eating behaviours and bullying. This last topic was included after talking to children, who reported dissatisfaction with body image and suffering bullying from classmates for being obese. Afterwards, homework activities which required family interaction and commitment to accomplish the goals were proposed. In addition, schools promoted healthy eating by displaying posters and selling nutritious food in the snack bar.There was no difference between groups before the intervention. The average age was 9 ± 2 years, average body mass index (BMI) was 19 kg/m2 and 55.4% were girls. The children in the control group showed a significant increase in BMI after the nine months of the study (p ≤ 0.01). BMI in the intervention group remained the same, but there was a significant increase in fruit consumption and physical activity (p < 0.05).
Ms Schneid Schuh said: “The implementation cost of the intervention was very low, at less than USD $0.20 per student. This indicates that it could be reproduced in other low resource settings.” She concluded: “This intervention in the school environment was able to stop an increase in BMI. This is an encouraging finding since obesity is rising in Brazil in general, and in Feliz in particular. Most importantly, being able to increase physical activity and fruit consumption in childhood may be crucial for building a healthy and happy life in the long run.”

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Pope Francis To Visit ESC Congress 2016 in Rome

Posted by fidest press agency su venerdì, 19 agosto 2016

papa francescoRome. The European Society of Cardiology (ESC) is proud to announce that His Holiness Pope Francis will visit ESC Congress 2016, the largest scientific summit on cardiovascular medicine. More than thirty-thousand health care professionals from around the world are expected to attend this year’s event in Rome. Pope Francis will address the gathering at the conclusion of the five-day congress on Wednesday, 31 August 2016.“The Pope’s visit is recognition of the significant efforts by the European Society of Cardiology and medical professionals worldwide to advance prevention, diagnosis and treatment of heart disease,” said ESC President, Professor Fausto Pinto. “We are honored to welcome Pope Francis.” According to the World Health Organization, cardiovascular disease is the world’s leading cause of mortality. It is responsible for more than 17 million deaths a year — or 31% of all deaths globally — according to the most recent data. The European Society of Cardiology brings together health care professionals from more than 120 countries to advance cardiovascular medicine and help people lead, longer healthier lives. ESC Congress, held annually at the end of August, presents more than 6,000 scientific abstracts, identifying the latest discoveries and breakthroughs in the fight against heart disease.

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New heart failure guidelines set to be launched at congress in May

Posted by fidest press agency su giovedì, 28 aprile 2016

Sophia AntipolisSophia Antipolis. New European Society of Cardiology (ESC) heart failure guidelines are set to be launched at Heart Failure 2016 and the 3rd World Congress on Acute Heart Failure in Florence, Italy. The world’s leading heart failure congress is the main annual meeting of the Heart Failure Association (HFA) of the ESC. It takes place 21 to 24 May in the historic sixteenth century Fortezza da Basso. Professor Gerasimos Filippatos, HFA president, said: “Journalists at the congress will be the first to hear the latest clinical advice in the 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure, which will be revealed on day one of the congress. Subsequent sessions are devoted to specific aspects of the guidelines including acute heart failure, co-morbidities, arrhythmias and devices, and chronic heart failure – providing plenty of material for stories.” Highly anticipated late breaking science will be presented in three sessions and feature state of the art discoveries from clinical trials, registries and basic science studies. More than 2 000 abstracts and clinical cases were submitted for presentation which is a new record and promises top quality research and news for the press. A highlights session will summarise the best findings of the abstract programme, selected and presented by experts. The full scientific programme is available here. This year’s event is expected to host more delegates than ever before, with 5 000 set to attend. The event attracts numerous professions, including cardiologists, basic scientists, cardiac nurses, intensivists, anaesthesiologists, and emergency room physicians. Members of the press should register now.The successful World Congress on Acute Heart Failure returns this year with debates, abstracts, and late breaking trials. Professor Filippatos said: “This is the place for the media to hear cutting edge developments in the cardiologiafast moving area of acute heart failure.”A novel session will see three clinical cases enacted in virtual patients created for the congress. Experts will guide the audience through these challenging cases and share their feedback and take-home messages. During four days packed with science there will be more than 100 scientific sessions and contributions from over 300 international leaders in the field. Industry representatives will present innovations and discuss products in the pipeline. The basic and translational science programme has been enhanced with nine pre-arranged sessions with renowned experts plus breakthrough abstract presentations. A local track features six sessions in Italian and English and is organised in collaboration with societies and experts from Italy. During the inaugural session, Karl Swedberg will give the Eugene Braunwald lecture on the success of neurohormonal and heart rate control in the treatment of heart failure. Luigi Tavazzi will give the Philip Poole Wilson lecture on new scenarios in medical science during the young investigator award session on basic and translational science. A new HFA Career Cafe will be held on Saturday morning giving young heart failure specialists, who have applied ahead of the congress, the chance to receive face to face career advice and recommendations from three world renowned experts. The congress theme is “Heart Failure: State of the Art” and reflects the launch of the new guidelines. Recommendations on the diagnosis and management of acute and chronic heart failure with drugs and devices, all based on the most up to date evidence, will be presented and discussed for the first time. Professor Filippatos said: “Sign up now to get the latest on hot topics in acute and chronic heart failure at the biggest international meeting in the specialty.” Also don’t miss the first public presentation of the 2016 European Guidelines on cardiovascular disease prevention in clinical practice. Be the first to know what the Task Force says by attending the session dedicated to this topic on Tuesday 24 May.

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