Fidest – Agenzia giornalistica/press agency

Quotidiano di informazione – Anno 31 n° 321

Posts Tagged ‘chemical’

Chemical Financial Corporation and TCF Financial Corporation Shareholders Approve Merger of Equals

Posted by fidest press agency su domenica, 9 giugno 2019

Chemical Financial Corporation (Chemical) (NASDAQ: CHFC) and TCF Financial Corporation (TCF) (NYSE: TCF) today jointly announced that at separate special meetings held today, each company’s shareholders approved the proposed merger of equals in which TCF will merge into Chemical. The combined holding company and bank will be headquartered in Detroit, Michigan and operate under the TCF name and brand following the closing of the transaction.“I am encouraged by the strong level of shareholder support received for this partnership and the accelerated shareholder value we expect it to create,” said Craig R. Dahl, TCF chairman and chief executive officer. “This positive shareholder response demonstrates a broad recognition of the shared strategic vision and complementary strengths of the two organizations. We look forward to bringing together the best of both banks to benefit our shareholders, customers, employees and the communities we serve.” “Today’s vote was an important step for us as we move forward with our focus on creating a premier Midwest bank,” said Gary Torgow, Chemical’s executive chairman. “As we become one company, we will be able to provide a more robust product set to a broader customer base, with limited overlap and disruption. With our increased scale and an enhanced competitive position, our new organization will be poised to thrive in today’s evolving banking environment.” Upon completion of the merger, the combined company will have over $45 billion in total assets and be a top 10 bank in the Midwest based on deposit market share. With over 500 combined branches across nine states, the new organization will have a substantial presence in key Midwest markets including Detroit, Chicago, Minneapolis, Milwaukee and greater Michigan.
The merger is expected to close in the third quarter or early fourth quarter of 2019, subject to satisfaction of customary closing conditions, including receipt of regulatory approvals.

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Alion to Support U.S. Chemical, Biological, and Nuclear Defense

Posted by fidest press agency su domenica, 21 gennaio 2018

washingtonWashington. The evolving threat of chemical, biological, radiological, nuclear, and high-yield weapons (CBRNE) is a reality at home and abroad. Countering these threats requires rapid research and solution development to ensure the safety of our war fighters and of American citizens. Alion is pleased to announce that it will assist the Department of Defense (DoD) with research and development against CBRNE weapons as the prime contractor on a potential $8.3 billion IDIQ contract vehicle. This work will be delivered through the Joint Program Executive Office for Chemical and Biological Defense’s (JPEO-CBD) Joint Enterprise Research, Development, Acquisition and Production/Procurement (JE-RDAP) omnibus contract.“It’s exciting to know that our R&D history and agile engineering expertise can come together through the JE-RDAP contract to put life-saving products into the hands of our warfighters,” said Jeff Murter, Deputy Group Manager for the company’s Rapid Solutions Group. “Our work on wearable sensors, modeling and simulation, miniaturization, and other next-gen solutions is exciting in its own regard, but using it to support this client against CBRNE threats means we are engineering solutions with a real mission and real people in mind.”This multi-award, 10-year contract allows for task and delivery orders to extend for up to five years after the expiration of the 10-year base ordering period. Work will include providing CBRNE defense systems, capabilities, equipment, supplies and material; radiological/nuclear defense systems; and information systems to the warfighter through November 1, 2027.Through this IDIQ contract vehicle, Alion will continue contributions to America’s CBRNE defense that began during WWII. As global tensions continue to shift and mount, the company’s ability to quickly assess and deliver new solutions will prove critical to the country’s defense and security.

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Dow Chemical to Merge with Du Pont?

Posted by fidest press agency su venerdì, 11 dicembre 2015

Warwick Business SchoolAn expert comment on the rumoured Dow Chemical Du Pont merger, John Colley, a Professor of Practice at Warwick Business School and an expert on large so-called mega-mergers, has made the following statement: “In a year likely to register a record volume of acquisitions globally, two of the USA’s oldest businesses appear set to merge in a $120Bn deal in a deal certain to be popular with shareholders.”The intention is to merge their respective divisions. This will create greater scale and scope economies, regional and divisional management savings and importantly higher market shares and more market influence. Ultimately this may mean less competition, less consumer choice and conceivably higher prices. However competition regulators in a number of markets will have plenty to say about these issues.”These regulatory concerns could jeopardise the deal. The Department of Justice showed its teeth earlier in the week with GE withdrawing from the sale of its consumer durables business to Electrolux. This was as a result of signs that the deal would not be cleared. More concerning, is the tag ‘merger of equals’ which normally precedes a botched integration. Clarity and unity of leadership in achieving merger benefits is critical to achieving the expected returns. Research shows that ambiguity in leadership usually results in a failed merger, just ask Daimler and Chrysler for one.
“Savings have been estimated at $3Bn a year. This is likely to be a conservative figure. Much will be through job reductions, so employees are unlikely to favour the deal. In process industries, such as chemicals, enormous scale economies can be achieved through merging and concentrating production on the biggest most modern plant located nearest to demand.”The newly created business will split into three new businesses, thereby avoiding the label of a chemicals conglomerate which attracts a discount in the share price. (Typically investors shun conglomerate shares due to low growth expectations.) Activist shareholders have been lobbying for a split.Their belief is that constituent businesses will have better stock market ratings separately, than as a whole. Overall the deal should create significant value in an industry which has struggled for growth in recent years. Petrochemicals and agrochemicals have been highly competitive markets with sluggish growth. The new businesses are likely to be plastics, agrochemicals and speciality chemicals.”

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Bloccare la proteina TRF2

Posted by fidest press agency su venerdì, 21 novembre 2014

Cancro-sintetizzata-molecola-che-blocca-proteina-tumoraleTRF2 è una proteina strutturale delle regioni terminali dei cromosomi (telomeri), che gioca un ruolo importante nel processo di trasformazione neoplastica. Bloccarla può rappresentare una nuova e valida strategia antitumorale. Un gruppo di ricercatori dell’Istituto Regina Elena (IRE) di Roma, coordinato da Annamaria Biroccio, ha sintetizzato un piccolo peptide in grado di interrompere i segnali cellulari ad attività tumorale di TRF2. Il lavoro è stato pubblicato oggi sulla rivista internazionale Journal of American Chemical Society.
Il progetto multidisciplinare nasce dalla collaborazione con i Chimici dell’università Federico II di Napoli e si fonda sull’osservazione che la proteina TRF2, attraverso il suo dominio TRFH è in grado di convogliare al telomero varie proteine che contribuiscono con la loro attività alla formazione del tumore. I ricercatori, basandosi su dati cristallografici disponibili in letteratura, hanno disegnato e sintetizzato un peptide che, legandosi con alta affinità al dominio TRFH di TRF2, inibisce i segnali coinvolti nel processo di tumorigenesi. Tale molecola non è stata scoperta per caso, ma tramite processi di ingegneria chimica, che hanno permesso la modulazione della sua funzionalità e l’ottimizzazione di determinate proprietà, allo scopo di trovare la molecola giusta.
Questi studi rappresentano il futuro della ricerca. “La bioinformatica – chiarisce Annamaria Biroccio – e nello specifico gli studi predittivi, permetteranno di ottimizzare quei processi che intercorrono tra la fase di ‘disegno’ e quella di selezione dei farmaci a bersaglio molecolare e permetteranno, conseguentemente, di abbattere i tempi e, non ultimo, i costi legati alla sperimentazione.”
“Le moderne tecniche di Rational Design e l’utilizzo di modelli bioinformatica- spiega Pasquale Zizza, primo autore dello studio – hanno consentito il disegno e la selezione di una molecola ad elevato potenziale applicativo in grado di bloccare le funzioni reclutanti di TRF2.”
“I risultati ottenuti – evidenzia Annamaria Biroccio – scaturiscono da uno studio più ampio, in collaborazione con il gruppo francese diretto dal Prof. Eric Gilson, in cui è stato identificato un ruolo non canonico della proteina telomerica TRF2. Il lavoro pubblicato sulla rivista “Nature Cell Biology” a Luglio del 2013, infatti, evidenziava come TRF2 possa contribuire allo sviluppo tumorale, non solo attraverso la sua già nota capacità di mantenere l’integrità telomerica, ma anche attraverso la modulazione di alcuni componenti del sistema immunitario.”“Lo studio appena pubblicato – sottolinea Ruggero de Maria, Direttore Scientifico IRE -rappresenta un esempio di come attraverso un approccio multidisciplinare sia possibile in tempi rapidi passare dall’identificazione di un bersaglio molecolare al disegno di un inibitore specifico.”

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Commemoration of the Syrian Chemical Attacks of August 21, 2013 Green Cross Calls for Immediate International Support of the Victims

Posted by fidest press agency su sabato, 23 agosto 2014

attacchi chimici sirianiZurich, Switzerland (ots) – A year ago, on August 21, 2013, several residential areas of Damascus, the Ghoutas, were hit by a mayor chemical weapons attack causing the death of an estimated 1.400 civilians and injuring many more. The world was shocked and under international pressure the Syrian government joined the Chemical Weapons Convention and assented to the OPCW-led destruction of its declared chemical weapons arsenals. But one year after the attacks it seems that the international furor over the use of toxic agents against civilians in Syria has subsided. The still-besieged Ghoutas have not received any substantial international aid and the survivors are still suffering from heavy after-effects due to their exposure to toxic agents. Green Cross is calling for immediate international support of the victims and points out the necessity to strengthen international efforts to ban all weapons of mass destruction from the region.
Green Cross has recently successfully implemented an emergency aid project in Ghouta together with the Syrian partner organization, Al-Seeraj. The project aimed at providing urgently needed medicine against the further spread of diseases within the population already weakened by the chemical attacks. But the ill and traumatized people need much more support. “It is a real humanitarian disaster that is taking place in the besieged areas”, says K. A., a woman aged 27, who has lost all her family members during the attack on Zamalka in Eastern Ghouta. She stayed in her besieged neighborhood despite all the horror and is devoting now all her strength as a medical assistant to the suffering people.
Since early 2008, Green Cross has supported local social-medical care projects in the Halabja Region in northern Iraq, infamous for the deadly poison gas attacks ordered by the regime of Saddam Hussein in 1988. These projects are focusing on the long-term sociological, psychological and physical health effects of those chemical attacks and show how important it is to support the victims even a long time after the event.
Falah Muradkhin, survivor of the 1988 attacks and who is today project coordinator of the local partner organization of Green Cross, Wadi Iraq, mourns the victims of the Ghouta attacks and points out that “25 years ago the technology was not available to send immediate news and reports to the world about what happened in Halabja. Today, however, the situation is different. The horrible pictures from the Ghoutas were quickly disseminated and seen by many people. Yet no action was taken to help the victims of the attacks and no adequate response has been seen either from the United Nations or from countries, also in Europe, which supposedly were involved in the development of Syria’s chemical weapon arsenals”. Green Cross is therefore calling on this day of commemoration for immediate international support of the forgotten victims of the Ghouta-attacks.
Green Cross is also supporting actively the establishment of a world truly free of chemical weapons and therefore calls on the remaining six non-State Parties – Angola, Egypt, Israel, Myanmar, North Korea and South Sudan – to join the CWC (Chemical Weapons Convention). And in view of the close relationship between all three classes of weapons of mass destruction – nuclear, chemical, and biological – Green Cross calls for the establishment of a Weapons of Mass Destruction (WMD)-free zone as a next step. “There will be no real security for the people living in this politically tense region as long as there are any weapons of mass destruction stockpiled”, concludes Dr. Stephan Robinson, Unit Manager (Water, Legacy) of Green Cross.

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American Chemical Society honors educators making sustainability part of the education of tomorrow’s scientists

Posted by fidest press agency su giovedì, 30 Mag 2013

WASHINGTON The American Chemical Society (ACS) has honored five individuals and teams who have incorporated concepts of sustainability into the chemistry education curricula for future scientists. As part of ACS’ mission to “advance the broader chemistry enterprise and its practitioners for the benefit of Earth and its people,” the Society’s Committee on Environmental Improvement (CEI) has recognized individuals or groups who have made exemplary contributions to the incorporation of sustainability in chemical education. The ACS is especially pleased to note that these awards reflect improvements at all levels of education from K-12 to community colleges to graduate degree programs.“Developing sustainable, chemical solutions to everyday problems — whether they be polymer coatings for solar panels, efficient vehicle batteries that will store energy or methods for purifying drinking water — these discoveries require new ways of thinking,” said ACS President Marinda Li Wu, Ph.D. “ACS is proud to announce that leading chemistry educators are stimulating the next generation of scientists to think in new ways to develop new, environmentally sensitive products and processes so that our Earth can continue to sustain us all.”The winners of the ACS-CEI Award for Incorporation of Sustainability into Chemistry Education:
Richard H. Jarmon, Ph.D., College of DuPage, Glen Ellyn, Ill.
Andrew Jorgensen, Ph.D., University of Toledo, Toledo, Ohio
Resa Kelly, Ph.D., San Jose State University, San Jose, Calif.
Cristina Chang, San Jose State University, San Jose, Calif.
Natalia Pavlovna Tarasova, Ph.D., D. Mendeleev University of Chemical Technology of Russia, Moscow, Russia
Joseph R. Vincente, East Side Community High School, New York, N.Y.
Andrea Swenson, East Side Community High School, New York, N.Y.

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Chemical and Drug Testing

Posted by fidest press agency su lunedì, 19 aprile 2010

AXLR8, an ambitious European Commission-funded initiative has launched today as part of growing international efforts to revolutionise chemical and drug safety testing with sophisticated “21st century” cell- and computer-based methods. A successful transition to 21st century toxicology could mean the end of animal testing as it exists today, sparing at least a million animals from suffering and death each year in the European Union alone. nToxicity data are needed to evaluate chemicals used in everything from cosmetics and household cleaners to pharmaceuticals, food additives, and pesticides. However, scientists and legislators across the EU and United States are coming to recognise that conventional tests, in which animals such as rodents, rabbits and dogs are given unrealistically large doses of chemicals, are too costly, time-consuming, and of uncertain relevance to human health effects to meet the demands for better and faster data as part of new chemicals regulation such as REACH. A recent report by the U.S. Food & Drug Administration estimates that new drug candidates have only an 8 percent chance of reaching the market, in large part because animal studies so often “fail to predict the specific safety problem that ultimately halts development”. Humane Society International and its affiliates are spearheading initiatives in the EU and U.S. to achieve this transition away from observing gross pathological effects in chemically overdosed animals to one based on studying how chemicals interact with “cellular pathways” in the human body at environmentally relevant exposure levels. Some of the globe’s largest consumer product, chemical and pharmaceutical companies – Dow, DuPont, Johnson & Johnson, Procter & Gamble, Unilever – have joined forces with HSI and its affiliates to add corporate support to help bring about the evolution in toxicology [13]. And in the EU, the HSI-envisioned AXLR8 initiative will bring together leading scientists to advise the European Commission regarding future research needs and priorities to transition towards 21st century toxicology. Recent advancements in molecular and cellular biology have made possible the realisation of the vision of 21st century toxicology. A range of new tools exist – such as functional genomics, proteomics, metabonomics, high data content screening and systems biology – that can be used for studying the effects of chemical stressors in the human body at a molecular and cellular level in a time- and cost-efficient manner. Rapid screening using high-throughput robotic automation means that thousands of substances can be processed in a single day. In this way data can be available to regulators in hours instead of days, weeks or even years, making future chemicals regulation more intelligent and responsive.

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Chemical information

Posted by fidest press agency su mercoledì, 19 agosto 2009

Washington. CAS, a division of the American Chemical Society, announced that it is on track to register the 50 millionth unique chemical substance in the CAS REGISTRY on September 7. REGISTRY is the most comprehensive and high-quality compendium of publicly disclosed chemical information. This milestone came quickly, since it was only 9 months ago that CAS registered its 40 millionth substance. In contrast, it took 33 years for CAS to register the 10 millionth compound in 1990. “The pace of discovery in molecular science is quickening,” said Dr. Mathew Toussant, Senior Vice President of Editorial Operations at CAS. “We are finding that the predominant source of new chemical substances is global patent literature.” REGISTRY is the only integrated comprehensive source of chemical information from a full range of patent and journal literature that is curated and quality controlled by scientists working around the world. For more than 100 years, CAS scientists and colleagues in several nations have meticulously analyzed and indexed publicly disclosed global scientific information to build up the unique REGISTRY resource that provides not only chemical names, the unique CAS Registry Number(R), and vital literature references but also ancillary information such as experimental and predicted property data (boiling and melting points, etc.), commercial availability, preparation details, spectra, and regulatory information from international sources. CAS scientists follow rigorous criteria that maintain the famously high quality and reliability of information in its REGISTRY. Scientists identify reputable sources and use consistent analysis before registering a substance. The CAS REGISTRY is available to scientists through CAS’ award-winning product, SciFinder(R), and its STN(R) family of products. With these advanced search and analysis technologies, CAS helps scientists find reliable information that is vital to their research process. http://www.CAS.org.

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Global Chemical Industry Announces

Posted by fidest press agency su sabato, 27 giugno 2009

chemicalRome on 7 July 2009Via di Ripetta 231, 10.00 hrs – 14.00 hrs The International Council of Chemical Associations (ICCA) commissioned Öko-Institut to contribute to this project and to support McKinsey & Company. Öko-Institut’s specific role was to conduct a critical review on the Carbon Life Cycle Analyses (cLCA). These cLCA calculations have been used in the project in order to quantify the CO2e emissions of selected chemical industry products over their whole life cycle in comparison to non-chemical industry product emissions and to assess the differences regarding in-use emissions due to performance difference between chemical and non-chemical products. The results of these calculations are presented in this study in two ways, the gross savings ratio and the net emission abatement. The report will be presented in the context of the G8 Summit, which will be debating energy and climate change issues during its meetings. Key speakers of chemical industry from Europe and Japan, international and European institutions and Italian government will have the floor. (chemical)

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