Fidest – Agenzia giornalistica/press agency

Quotidiano di informazione – Anno 31 n° 344

Posts Tagged ‘consensus’

First European consensus on clinical use of dimethyl fumarate

Posted by fidest press agency su giovedì, 22 novembre 2018

The Journal of the European Academy of Dermatology and Venereology (JEADV)1 has published the first European expert consensus on clinical use of dimethyl fumarate in moderate-to-severe plaque psoriasis. The consensus report was drawn by 10 dermatologists from across Europe with extensive clinical experience in managing psoriasis patients and significant experience of using FAEs in clinical practice. Some of them also have experience in drawing up national and European-level clinical Guidelines in psoriasis, including the 2015 update of the European S-3 Guidelines on the systemic treatment of psoriasis.The main conclusion of the Consensus is that the favourable safety profile of fumaric acid esters (FAEs) together with their long-term efficacy provide a first-line therapeutic option to achieve sustained disease control for patients with moderate-to-severe chronic plaque psoriasis, when the disease cannot be adequately controlled with topical treatments and phototherapy. Also, the Consensus states DMF is considered to be the main active ingredient accounting for the clinical effects in psoriasis.
In 2017, the European Medicines Agency (EMA) approved a new oral formulation of dimethyl fumarate (Skilarence®) for the treatment of adult patients with moderate-to-severe chronic plaque psoriasis in need of systemic therapy, only containing DMF, considered to be the main active ingredient accounting for the clinical effects in psoriasis.4 This approval gave rise to a new oral treatment option for patients with moderate-to-severe chronic plaque psoriasis across Europe. The Phase III randomized BRIDGE study compared the efficacy and safety of Skilarence® and Fumaderm® vs. placebo in adult patients with moderate-to-severe chronic plaque psoriasis and it demonstrated that Skilarence® was non-inferior to Fumaderm®6 (a combination of FAEs plus 3 monoethyl fumarate salts), with a similar safety profile.4 Nevertheless, for many aspects of psoriasis treatment, there is no published evidence and expert consensus was needed to guide best clinical practice.
Psoriasis is a chronic immune disease that appears on the skin. It affects an estimated 7.8 million adults in Europe and approximately 125 million people worldwide.17 It is a non-contagious disorder that accelerates the growth cycle of skin cells and results in thick scaly areas of skin. It is associated with an increased risk of early mortality, an increased prevalence of co-morbidity such as psoriatic arthritis, metabolic syndrome, and can have significant psychosocial impact which adversely affects patients’ quality of life. The most common form of psoriasis, called plaque psoriasis, appears as red, raised areas of skin covered with flaky white scales, which may be itchy and painful and can crack and bleed. Despite different treatment options existing, many people with plaque psoriasis continue to struggle with the ongoing, persistent nature of this chronic disease.

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Construire les bases d’un consensus politique et social sur les questions migratoires

Posted by fidest press agency su venerdì, 25 novembre 2016

migrantesAu cours de la dernière décennie, et plus particulièrement des derniers mois, l’Union européenne a dû faire face à une augmentation des conflits relatifs aux questions migratoires. Ces conflits ont atteint un tel degré que le retour à l’équilibre, dans un tel contexte, sera une tâche difficile pour tous les acteurs, à toutes les étapes. Toutefois, si les dirigeants européens sont incapables de prendre les décisions politiques et d’engager les actions appropriées, le processus d’intégration de l’UE sera tout simplement en danger.Dans sa première partie, ce Policy paper d’Yves Pascouau, chercheur senior associé à l’Institut Jacques Delors et directeur à l’European Policy Centre, cherche à faire le point sur les oppositions actuellement à l’œuvre au sein de l’UE. Alors que les tensions au niveau politique mettent en évidence l’existence de conflits entre les États membres de l’UE, un autre conflit – plus inquiétant – s’installe : il s’agit de la distance, voire de la méfiance croissante entre les citoyens et le projet européen. Dans ce contexte, il convient également de s’interroger sur le rôle des médias. Partant de ce constat, la deuxième partie du Policy paper affirme qu’il est encore possible de parvenir à un consensus et de revenir à une UE source de prospérité, et non nid à problèmes. Cependant, ce Policy paper estime qu’une approche dite « top-down » du Conseil européen ne suffit pas et ne fonctionnera pas. Il est indispensable de relancer une approche pédagogique, de manière à ce que les citoyens puissent à nouveau comprendre et avoir confiance dans les actions et projets de l’UE. Ceci implique deux types d’actions :
• À court terme, tous les acteurs à l’échelle européenne et nationale doivent tenir leurs promesses pour montrer que les décisions prises sont mises en œuvre et produisent des effets.
• À moyen terme, ces mêmes acteurs doivent initier un processus stratégique pour, à long terme, comprendre, préparer et adopter des réponses appropriées au phénomène migratoire. (photo: migrants)

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CEC urges efforts at global consensus after Syrian ‘chemical attack’

Posted by fidest press agency su giovedì, 29 agosto 2013

The Conference of European Churches strongly condemns the use of chemical weapons last week in Syria that is believed to have killed more than 450 people and injured more than 3,500. It is a severe and alarming escalation in two-and-half years of atrocities in the conflict engulfing the region.CEC General Secretary Rev. Dr Guy Liagre said in a statement on August 28, “As the first known use of chemical weapons in the 21st Century, this is alarming for citizens of the world and the region. We are urging member churches to pray and encourage their leaders to voice their concern on behalf of the victims, the helpless and innocent people who continue to suffer in the conflict.”As the U.N. Security Council considers its response to this heinous act, we pray that  any decision taken will primarily consider the good of the Syrian people and not the exigencies of politics. Every effort among global leaders must continue to be made to reach an enlightened consensus on how to deal with the events around the chemical attack using international law and institutions.”We urge CEC member churches to pray for an end to the conflict in Syria and the protection of the rights of the most vulnerable within the framework of international human rights and in a manner that does not precipitate a worsened conflict.”

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To fewer child deaths and improves economy

Posted by fidest press agency su giovedì, 30 giugno 2011

Bishkek. Despite improvements in the past decade, 22 per cent of all deaths among children under-five in the Kyrgyz Republic are still caused by undernutrition, according to a report launched today. Besides the loss of lives, the burden of undernutrition in the Kyrgyz Republic is also substantial in economic terms: estimated to be US$32 million annually. Scaling up nutrition interventions, therefore, is crucial to prevent loss of children`s lives and is a strategic economic investment with high returns, according to the Situational Analysis – Improving Economic Outcomes by Expanding Nutrition Programming in the Kyrgyz Republic. The report was released at a meeting jointly organized by the Ministry of Health, UNICEF and the World Bank.
In Kyrgyzstan, three-quarters of the country’s salt is iodized and ten percent of wheat is fortified. But further is needed:
• Iodizing all salt sold will reduce iodine deficiency resulting in a US$500,000 annual benefit due to increased worker productivity.
• Fortifying all of the country’s flour with iron, folic acid, and other B vitamins will improve the quality of the diet. The government’s efforts to fortify wheat flour as a public health intervention needs to be further supported.
“At least US$6.2 million of the country’s economic losses from undernutrition can be prevented by scaling up existing nutrition programs in the Kyrgyz Republic,” said Tamer Rabie, a World Bank Senior Health Specialist. “Development partners need to capitalize on the successes achieved by the Government and assist it in its scaling up of programs such as salt iodization and flour fortification,” he added. Good nutritional practices includes exclusive breastfeeding for the first six months, timely introduction of adequate complementary feeding, increasing vitamin and mineral intake, as well as addressing severe acute malnutrition in children. The international development community has recognized the need to scale up nutrition interventions; the potential for public-private partnerships, and there is consensus around a common framework for action.

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Dalla crescita allo sviluppo

Posted by fidest press agency su giovedì, 11 novembre 2010

Seul. Costruire un nuovo Consenso sullo sviluppo per superare il fallimentare Washington Consensus del passato. Lo richiede Oxfam Italia ai leader del G20 in un documento diffuso oggi. Dal 1981 al 2001, quando il Washington Consensus era la dottrina incontrastata, l’economia mondiale è cresciuta di 19mila miliardi di dollari, ma le persone che vivono in povertà estrema hanno beneficiato solo del’1,5% di questa crescita. E’ per questo necessario far sì che l’economia mondiale abbia ricadute positive anche per i paesi poveri. Il nuovo Consenso dovrebbe prevedere il sostegno finanziario a sanità e istruzione nei paesi in via di sviluppo e aiuti ai contadini poveri. “Un focus solo sulla crescita non è sufficiente per affrontare la povertà. Troppo spesso, in passato, ai più poveri sono stati negati i benefici della crescita”, avverte Farida Bena, portavoce di Oxfam Italia. “Il G20 deve mostrare che questa volta sarà diverso. Milioni di persone sono state spinte nella povertà estrema dalla crisi economica e stanno pagando il prezzo dei tagli a sanità, istruzione e spesa sociale” Secondo stime della Banca Mondiale, la crisi mondiale ha trascinato 64 milioni di persone in più nella povertà estrema, costringendole a vivere con meno di 1,25 dollari al giorno. Una ricerca commissionata da Oxfam mostra inoltre che 56 paesi poveri registrano un buco fiscale di 65 miliardi di dollari a causa della crisi economica. Come primo membro non appartenente al G8 a ospitare il vertice dei capi di stato del G20, la Corea del Sud ha fatto dello sviluppo una parte centrale della sua agenda, ponendo l’accento sulla crescita dei paesi poveri. Ma Oxfam è preoccupata che i progressi nella lotta contro la povertà possano andare in fumo a causa delle discussioni sui tassi di cambio e sulle politiche monetarie. “Il G20 ha la possibilità di fare importanti progressi. Sarebbe una tragedia se le persone povere diventassero vittime di un conflitto sulle valute”, avverte Takumo Yamada, analista politico di Oxfam.
L’Italia può giocare un ruolo importante al vertice. Oxfam chiede al nostro paese di promuovere l’adozione di una tassa dello 0,05% sulle transazioni finanziarie. La misura è già oggetto di una proposta di legge bipartisan presentata recentemente alla Camera. “Più in generale, Oxfam chiede al G20 di accordarsi su un pacchetto di misure per aiutare i paesi poveri, che includa il mantenimento delle promesse sugli aiuti da parte dei paesi ricchi; una regolamentazione per proteggere le persone povere dell’accaparramento della terra (land grabbing), che ha visto enormi fasce di aree coltivabili finire sotto il controllo di imprese e governi stranieri; azioni per limitare la speculazione sui mercati delle materie prime agricole; l’attribuzione di un vero peso politico ai paesi poveri nelle decisioni sull’economia mondiale che li riguardano. Per raggiungere quest’ultimo obiettivo, Oxfam propone di assegnare ai paesi in via di sviluppo almeno tre seggi al G20 e di intraprendere una riforma radicale del Fondo Monetario Internazionale.

Posted in Economia/Economy/finance/business/technology, Estero/world news | Contrassegnato da tag: , , , | Leave a Comment »

Obama’s Meeting with President Lee of Korea

Posted by fidest press agency su venerdì, 3 aprile 2009

Excel Center, London President Obama met  with South Korean President Lee Myung-bak and discussed the global economic crisis, North Korea, and other areas of cooperation. The South Korean leader accepted President Obama’s invitation to visit Washington on June 16. The two leaders agreed to work closely to take strong measures to stimulate their economies and to build international consensus on reform of the international regulatory and supervisory system. They both stressed the importance of avoiding protectionism and economic nationalism. President Obama expressed his strong commitment to the U.S.-ROK alliance, which is essential to maintain peace and security on the Korean Peninsula and in Northeast Asia, and pledged continued cooperation in the ongoing joint efforts to strengthen the alliance further. The two presidents agreed that the U.S.-Korea Free Trade Agreement could bring benefits to both countries and committed to working together to chart a way forward. Both leaders share a vision for broadening and modernizing the Alliance to address the challenges of the 21st Century and decided to explore ideas for increasing regional and global cooperation at their meeting in June. They discussed the issue of North Korea and promised to continue close cooperation in the effort to peacefully and verifiably eliminate North Korea’s nuclear programs, weapons and materiel through Six-Party Talks. In that regard, they urged North Korea to abide by the resolutions of the U.N. Security Council and agreed on the need for a unified response by the international community in the event that North Korea launches a long-range missile. President Obama expressed appreciation for South Korea’s contributions and support for the international effort to promote stability and to assist reconstruction in the Afghanistan-Pakistan region. They promised also to continue to find ways to cooperate in addressing global challenges such as climate change and clean energy technologies.

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