Fidest – Agenzia giornalistica/press agency

Quotidiano di informazione – Anno 32 n° 106

Posts Tagged ‘devasting’

Two Rare and Devastating Neurodegenerative Disorders

Posted by fidest press agency su domenica, 10 febbraio 2019

Neurogene, Inc., a company with a mission to bring life-changing medicines to patients and families affected by rare neurological diseases, today announced that researchers presented preliminary, unpublished “proof of concept” data in mice evaluating the safety and efficacy of adeno-associated virus (AAV) gene therapy for AGU and CMT4J, two rare neurological diseases, at the 15th Annual WORLDSymposiumTM conference in Orlando, Florida.
The potential therapies are being investigated under a collaboration agreement between Neurogene and UT Southwestern Medical Center through multiple sponsored agreements. Neurogene provides financial support for these and other related research projects, including pre-clinical studies for AGU and CMT4J.AAV gene therapy is being investigated as a potential treatment for aspartylglucosaminuria (AGU), a neurodegenerative disease caused by dysfunction of the AGA gene. The unpublished data, which have not been peer reviewed, consider the safety and efficacy of gene therapy for these diseases in mice in support of potential future clinical trials. Xin Chen, Ph.D., Instructor of Pediatrics at UT Southwestern Medical Center, presented data evaluating the effects in mice lacking a functional AGA gene, using intravenous or intrathecal administration with low and high doses, and data were reported for early symptomatic mice. Dr. Chen’s team reported data indicating AGU gene therapy resulted in dose-dependent, complete or near-complete elimination of toxic substrate in central and peripheral tissues and body fluids and that treatment was well-tolerated at supraphysiological levels.

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After devastating hurricane, community unites in reconstruction

Posted by fidest press agency su martedì, 17 aprile 2018

ROSEAU, Dominica — Hurricane Maria, a Category 5 storm, was one of the most severe Atlantic hurricanes on record. When it swept through the Caribbean some seven months ago, the destruction it left in its wake was staggering—homes destroyed, agricultural fields ruined, and communities decimated. International media coverage at the time rightfully focused on the loss and tragedy that the people of the islands had suffered.But in the months since, another story has unfolded in the Caribbean—one that is hopeful, positive, and not commonly told. It is the story of communities, throughout the islands, that have discovered in tragedy the power of unity, cooperation, and collective action to rebuild the physical environment and strengthen the social and spiritual connections that bind neighbors together. It is these connections that are essential for resilience in times of trial.When natural disasters strike, communities that are united in their efforts “are more capable of taking meaningful and effective steps to respond and recover,” wrote the Baha’i International Community (BIC) in a statement published in May 2016. “[E]xperience has shown that people can exhibit remarkable resilience, selflessness, resourcefulness, and creativity in such times.”
Kalinago territory, Dominica, where the community rallied together to build greenhouses in which seedlings could be sprouted to help restore the agricultural fields that were decimated by the hurricaneSLIDESHOW. The island of Dominica is one such example. Though relatively small in size, the local Baha’i communities on the island saw themselves not as helpless victims, but as protagonists in the transformation of their physical and social environments.In the Kalinago territory of Dominica, a primarily rural and indigenous region that was particularly hard hit by Hurricane Maria, aid was slow to reach the area in the storm’s aftermath, with food, water, and other supplies that were earmarked for the region never making it out of Roseau, the capital city.Recognizing the critical needs of their neighbors in the weeks following the storm, the Baha’is in the area were able to bring together community leaders, neighbors, friends, and others to consult on what they could do given the resources available to them. They decided to build several greenhouses to quickly re-establish food crops that had been decimated by the storm. Several residents offered their land to be used for the greenhouses where seeds could be planted and also plots of land where, later, the resulting seedlings could be transplanted.
Friends and neighbors gather in front of a greenhouse they constructed together. The community in this part of the remote Kalinago territory has begun to hold classes for children and young adolescents on the site, as well as prayer gatherings open to all.SLIDESHOW
11 imagesDrawing on what was being learned in Kalinago, the Newtown neighborhood in Roseau also gathered to consult about how its inhabitants could take charge of the reconstruction efforts in their own community. On a Sunday in early January, dozens in the neighborhood discussed what needed to be done most urgently in the wake of the damage left by Hurricane Maria.As residents consulted, there was hope present at the meeting in Newtown. Together they made plans to remove the logs and rubbish that were clogging the harbor and blocking access to the ocean, which is vital to their fishing community. Inspired by the work in the Kalinago territory, they decided that they could use some of the lumber retrieved from the bay to build a greenhouse where seeds could be sprouted rapidly and distributed for planting at farms whose crops had been destroyed.
At first, the only seeds they could obtain for the greenhouses were for bok choy, a vegetable unfamiliar to the people of the region. But they planted it anyway, and soon developed recipes for the leafy green that families shared with each other. Later they were able to plant additional crops such as pumpkins, beans, carrots, cabbages, lettuce, watermelon, chives, tomatoes, parsley, and okra. In the months since the greenhouses were constructed, the seedlings grown there have been used to establish crops and provide food for the inhabitants of several villages in the region. The community has also worked to assist other endeavors, such as building a new roof for the community library and obtaining supplies for a few schools in the territory.

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Supporting haitian-led food security

Posted by fidest press agency su sabato, 6 febbraio 2010

Friday, February 12, 2010 from 2pm-5pm at WFP headquarters in Rome, Italy.  On the one month anniversary of the devastating earthquake in Haiti, the Haitian Agriculture Minister Joanas Gue will convene a high level meeting to discuss the country’s medium and long-term agricultural development, food security and nutrition planning process.  This event represents the global kickoff of the agriculture pillar for the Haiti Redevelopment Plan and is part of the broad international mobilization to support the reconstruction of Haiti.  Jacques Diouf, Director General of the Food and Agriculture Organization (FAO), Josette Sheeran, Executive Director of the World Food Programme (WFP), and Kanayo Nwanze, President of the International Fund for Agricultural Development (IFAD) will join Minister Gue in discussing the need for global, regional and national leadership and coordination by the UN organizations. Bilateral donors including the United States, represented by Cheryl Mills, Counselor to the U.S. Secretary of State Hillary Clinton, Brazil, and others will participate in this discussion addressing the role of donor participation in the planning and implementation process.  Other invited speakers include representatives from the World Bank, the Inter-American Development Bank, the UN High-Level Task Force for the Global Food Crisis, the UN Haiti Special Envoy and the Inter-American Institute for Cooperation in Agriculture.  Attendance at this event is by invitation only.  Invitations have been extended to members of the Global Partnership for Food, Nutrition and Agriculture Security including the Haitian and global private sector leaders as well as foundations and non-governmental organizations interested in supporting Haiti.

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