Fidest – Agenzia giornalistica/press agency

Quotidiano di informazione – Anno 31 n° 321

Posts Tagged ‘Human Reproduction’

Merck destina 1,5 milioni di Euro al Grant for Fertility Innovation (GFI) per il periodo 2016/17

Posted by fidest press agency su venerdì, 8 luglio 2016

merckDarmstadt, Germania. Merck, azienda leader in ambito scientifico e tecnologico, ha annunciato oggi che continuerà a sostenere il progresso scientifico nel campo della fertilità attraverso il Grant for Fertility Innovation (GFI).
Nel periodo 2016/17 a questo programma saranno destinati finanziamenti per un totale di 1,5 milioni di Euro. L’annuncio è stato dato nel corso del 32° congresso annuale della European Society of Human Reproduction and Embryology (ESHRE) che si sta svolgendo a Helsinki, Finlandia.Il GFI, lanciato nel 2009 all’ESHRE, è dedicato a trasformare i più innovativi progetti di ricerca traslazionale nel campo della fertilità in soluzioni concrete che migliorino i risultati delle tecniche di procreazione medicalmente assistita (PMA). Quest’anno, sono stati selezionati 6 progetti vincitori tra le 112 candidature provenienti da tutto il mondo con l’obiettivo comune di aumentare le possibilità per le coppie di concepire un bambino. il finanziamento ad ogni progetto sarà suddiviso in tre tranches, che saranno assegnate al raggiungimento di specifiche fasi della ricerca.
“Il Grant for Fertility Innovation testimonia il nostro straordinario impegno a migliorare i risultati nei pazienti che hanno bisogno di nuove soluzioni per la fertilità” ha affermato il Dottor Steven Hildemann, Global Chief Medical Officer and Head of Global Medical e Safety di Merck. “Il GFI ha già permesso ai ricercatori più meritevoli di accelerare scoperte scientifiche e ricerca traslazionale per la cura della fertilità, utilizzando un’ampia rete globale di competenze, frutto della collaborazione tra il mondo accademico e l’Azienda”.Questi i premiati del GFI, annunciati nel corso della cerimonia che si è svolta il 5 luglio in occasione del Congresso ESHRE.
– Stephen Andrew Krawetz, Ph. D. – Wayne State University School of Medicine, Detroit, USA – Progetto: “A Retrospective Controlled Cohort Study of Sperm RNAs Guiding the 2 Treatment of the Idiopathic Infertile couple”
– Lynne O’Shea, B.Sc. (Hons.), Ph. D. – UCD School of Medicine and Medical Science, University College Dublino, Irlanda – Progeto: “Using a biomarker of oocyte quality to improve embryo selection during assisted 1 reproduction”
– Paola Piomboni, Ph. D., Ricercatore – Università di Siena, Italia – Progetto: “Exosomal Profile of the Receptive Endometrium: A source of non-invasive biomarkers for Guiding of a Successful Embryo Implantation”
– Qingling Yang , Ph. D.– Reproductive Medical Center of the first Affiliated Hospital of Zhengzhou University, Cina – Progetto: “Telomere length test of cell free genomic DNA in spent embryo medium as a non-invasive biomarker for assessing embryo developmental potential”
– Professor Ernest Hung Yu Ng, Professor William Shu -biu Yeung – University of Hong Kong, Cina – Progetto: “Human embryonic stem cell-derived trophoblastic spheroids (BAP-EB) as a predictive tool for endometrial receptivity and pregnancy rate of in vitro fertilization treatment”
– Professor Fulvio Zullo – Università Magna Graecia di Catanzaro, Italia – Progetto: “Periostin a new non-invasive parameter for evaluating oocyte/blastocyst quality and its impact on endometrial receptivity”

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Women with miscarriage have good chance of birth

Posted by fidest press agency su lunedì, 4 luglio 2011

Pregnancy in the 26th week.

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Stockholm, Sweden: Women who suffer from unexplained recurrent miscarriage (RM) need to know how long it might take them to achieve a live birth if they are not to lose hope and give up trying for a baby. There is currently no evidence-based treatment for RM, and therefore accurate counselling on the chances of achieving a live birth is essential, a Dutch researcher told the annual conference of the European Society of Human Reproduction and Embryology today (Monday). Dr. Stef Kaandorp, from the Centre for Reproductive Medicine, Academic Medical Centre, Amsterdam, The Netherlands, said that his group’s research was the first to look at time to natural conception in women with RM, and that its results would help health professionals to advise and treat patients appropriately. In a subset of the ALIFE study, which investigated the effect of aspirin alone or combined with low-molecular-weight heparin, compared to placebo, on the live birth rate in women with unexplained RM, the researchers looked at the length of time between the moment of randomisation to the moment of the first day of last menstruation before the subsequent pregnancy. 251 women were included in the subset, and the mean age at the time of diagnosing unexplained RM was 34 years. The women had all had at least two miscarriages with an upper gestational age of 20 weeks. 213 women became pregnant during the period February 2004 to July 2009. 139 had a live birth, 69 a miscarriage, two an ectopic pregnancy, two a termination of pregnancy and one had an intra-uterine foetal death. The median time to a subsequent pregnancy, irrespective of outcome, was 21 weeks. The cumulative incidence of natural conception was 56% after six months, 74% after 12 months, and 86% after 24 months of which 65% resulted in a live birth. The researchers now intend to follow up their work by looking at the time it took to achieve a live birth as opposed to simply time to pregnancy. “This will be important in counselling these women for their future pregnancy attempts,” said Dr. Kaandorp. “We hope that our work will encourage health professionals to avoid non evidenced-based and potentially harmful treatments for couples. For example, aspirin and low-molecular-weight heparin are still being used, even though the ALIFE study showed clearly that there is no evidence that they are helpful. Abstract no: O-022, Monday 10.15 hrs CEST (Hall A4)

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66% of women with recurrent miscarriage give birth

Posted by fidest press agency su lunedì, 4 luglio 2011

Microchimerism. There is two-way traffic of im...

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Stockholm, Sweden: The first long-term follow-up study to look at the chances of having a live birth after recurrent miscarriage (RM) – defined as at least three consecutive pregnancy losses – found that approximately two-thirds of women with RM had at least one live birth after referral to specialist investigation, a researcher told the annual conference of the European Society of Human Reproduction and Embryology today (Monday). Ms Marie Lund, a medical intern and research assistant at the Rigshospitalet Fertility Clinic, Copenhagen University Hospital, Denmark, said that her team’s research would help give couples a more realistic prognosis of their chances of having a child after RM. The researchers studied the records of 987 women with a minimum of three consecutive miscarriages, who had been referred to a specialist RM clinic between 1986 and 2008. Using data from the National Danish Birth Register they were able to see how many of the women had achieved a live birth after referral to the clinic. They also looked at the impact of maternal age at the time of referral, and the number of previous miscarriages as prognostic markers for future live births. The ages of the women at referral to the clinic ranged from 20 to 46 years. There are a number of possible reasons why some women attending the clinic did not have a live birth after referral, according to the researchers. One reason could be that they continue to miscarry in all subsequent pregnancies, but others could simply be due to increased age at each attempt, or damage to the Fallopian tubes caused by post-miscarriage pelvic inflammation. Additionally, the couple may eventually give up trying for a pregnancy due to fear of another miscarriage, or the pregnancy attempts are given up due to divorce. Most studies of RM to date have looked at miscarriage rate in the next pregnancy as an outcome measure. “Because an essential part of the management of couples with RM is to be able to advice on the prognosis for future pregnancy outcome, we performed this study to investigate the outcome measure of live birth after a certain time period, since we believe this is more relevant from the patient’s perspective and also more transparent than just looking at miscarriage rate in the next pregnancy. We hope that estimating the chances having a live-born child will give couples affected by RM a more realistic prognosis for future pregnancy success,” Professor Christiansen concluded. Abstract no: O-021 Monday 10.00hrs CEST (Hall A4)

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