Fidest – Agenzia giornalistica/press agency

Quotidiano di informazione – Anno 33 n° 338

Posts Tagged ‘medicine’

What if an AI won the Nobel prize for medicine?

Posted by fidest press agency su giovedì, 1 luglio 2021

Every July The Economist publishes a collection of stories that ask: What If? They imagine possible scenarios, set a few years or a few decades into the future, and then report on them in our characteristic style. The idea is to create what looks like an Economist article that has somehow reached us from the future through a crack in the space-time continuum. Journalists don’t usually get to write science fiction, so this is all great fun to do, and our aim is to provide an entertaining, provocative and mind-stretching read for the July 4th weekend. The theme of this year’s collection is the future of health. In stories that range in time from 2025 to 2055, we consider subjects from biohacking with mRNA to deadly heat waves, and from personalised nutrition to the health benefits of having pets on the Moon. Each scenario is made up, but is grounded in historical fact, current speculation and real science. The different stories in each year’s collection do not present a unified narrative—as the editor of this collection, I’m thankfully not required to maintain continuity across some kind of Economist Cinematic Universe—but are set in different futures, and can and do contradict each other.Inevitably, the pandemic and its impact are lurking in the background of several of these scenarios, though that is not their main focus. But the broader lesson that can be drawn from them, as from the pandemic, is the value of being prepared for future health emergencies. The prospect of a pandemic has been talked about for years, even though there was no way of predicting its timing or severity. But heat waves, obesity, dementia and antibiotic resistance are all looming health crises that are entirely predictable and deserve to be taken far more seriously. As with most science fiction there is, in short, a serious point to these tales. A selection of this year’s stories appears below, and you can find the full collection at economist.com/what-if-2021. We hope you will enjoy reading them. Tom Standage Deputy editor, The Economist, and editor, What If? font: The Economist

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Pubblicati nel New England Journal of Medicine i dati di Fase 3 del vaccino a dose singola contro il COVID-19 di Johnson & Johnson

Posted by fidest press agency su sabato, 24 aprile 2021

NEW BRUNSWICK, N.J. Johnson & Johnson (NYSE: JNJ) (l’Azienda) ha annunciato oggi la pubblicazione sul New England Journal of Medicine dei dati primari dello studio clinico di Fase 3 ENSEMBLE per il proprio vaccino a dose singola contro il COVID-19, sviluppato da Janssen, azienda farmaceutica del gruppo Johnson & Johnson. La pubblicazione dell’analisi primaria segue i dati di efficacia e sicurezza annunciati a gennaio, dimostrando che lo studio ha soddisfatto tutti gli endpoint principali primari e secondari, e ha rilevato che il vaccino a dose singola contro il COVID-19 di Johnson & Johnson ha prevenuto l’ospedalizzazione e la morte in tutti i partecipanti allo studio 28 giorni dopo la vaccinazione.Questi dati hanno dimostrato che, nonostante l’alta prevalenza di varianti emergenti di SARS-CoV-2 tra i casi di COVID-19 nello studio, compresa la variante sudafricana del ceppo B.1.351 e la variante del ceppo P2 individuata in Brasile, l’efficacia del vaccino è stata trasversale contro l’infezione sintomatica, e il vaccino ha mostrato protezione contro l’ospedalizzazione e la morte correlate a COVID-19 a 28 giorni dalla vaccinazione. I dati dello studio indicano l’inizio dell’efficacia 7 giorni dopo la vaccinazione, la prevenzione dell’ospedalizzazione e della morte La protezione è stata generalmente trasversale tra le etnie e i gruppi di età, compresi gli adulti sopra i 60 anni (N=14.672), e quelli con e senza comorbidità.L’efficacia è iniziata in modo evidente sette giorni dopo la vaccinazione per le forme gravi/critiche della malattia e 14 giorni dopo la vaccinazione per le forme da moderate a gravi/critiche. È importante notare che l’efficacia del vaccino ha continuato ad aumentare circa otto settimane dopo la vaccinazione, che è la durata media del follow-up richiesto dalla Food and Drug Administration (FDA) degli Stati Uniti. I dati aggiuntivi raccolti dopo l’annuncio dei risultati2 non hanno evidenziato riscontro di un calo della protezione nel tempo, dopo aver seguito circa 3.000 partecipanti per 11 settimane e 1.000 partecipanti per 15 settimane.Le varianti osservate in un’analisi in corso nello studio ENSEMBLE includono la variante B.1.351 (20H/501Y.V2), che è stata identificata nel 95% dei casi di COVID-19 in Sudafrica, e la variante del ceppo P2, che è stata identificata nel 69% dei casi di COVID-19 in Brasile. In Sudafrica, l’efficacia del vaccino è stata mantenuta al 64% contro le forme da moderate a gravi/critiche della malattia e all’81,7% contro le forme gravi/critiche al giorno 28 dopo la vaccinazione. L’efficacia è stata mantenuta anche nei partecipanti in Brasile, con il 68,1% di efficacia contro le forme da moderate a gravi/critiche della malattia e l’87,6% contro le forme gravi/critiche. Font: https://www.janssen.com/emea/our-focus/infectious-diseases-vaccines/respiratory-infections/covid-19.

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Pandemia e famiglie senza cure e medicine

Posted by fidest press agency su domenica, 6 dicembre 2020

I numeri della pandemia continuano a crescere e nel mondo. Sono oltre 62,5 milioni i casi confermati con quasi 1,5 milioni di morti. L’impatto del virus produce conseguenze medico-sanitarie, ma anche psicologiche, sociali, economiche e politiche, amplificate purtroppo per le persone, le famiglie, i gruppi sociali, i Paesi più fragili e più poveri.Offrire una risposta rapida ed efficace, garantendo nel contempo che l’assistenza necessaria raggiunga i più bisognosi, è fondamentale. Chi vive nella povertà, è povero di tutto, anche di farmaci e la sua salute è più vulnerabile. La priorità deve essere quella di adottare le misure adeguate che garantiscano a tutti l’accesso ai vaccini contro il Coronavirus e alle tecnologie essenziali necessarie per assistere i malati. Se proprio bisogna privilegiare qualcuno, questi dovrebbero essere i più poveri.Al di là delle cure sperimentali costosissime che restano appannaggio dei più ricchi, anche per l’accesso alle cure ordinarie in molti paesi del mondo si verifica una vera e propria ‘selezione sociale’.Negli Stati Uniti, in città come Chicago, gli afroamericani rappresentano solo il 30% della popolazione, ma costituiscono invece più del 50% dei casi di contagio e circa il 70% dei decessi per il COVID-19. Senza contare le conseguenze sulla salute mentale, già visibili su coloro che appartengono ai gruppi sociali più colpiti dalle conseguenze socio-economiche della pandemia.Quanto si è osservato negli Stati Uniti si riproduce nei paesi del ‘sud globale’, dove, accanto a una maggiore incertezza sulle stime quantitative vi è la preoccupazione per i sistemi sanitari e di protezione oggettivamente più fragili, spesso con carenza di respiratori, di ossigeno, di personale.Milioni di famiglie povere e impoverite oltre ad essere più esposte al rischio di contagio, in questa emergenza, rischiano di rimanere senza cure e medicine per mancanza di soldi, oppure non accedono più ad alcuni servizi.Secondo uno studio dell’OMS, la pandemia sta causando una crisi massiccia dei servizi di salute mentale, neurologica e di cura delle dipendenze da sostanze, fino, in molti casi, alla completa interruzione dei servizi. I motivi di questa crisi sono da ricercarsi nel numero insufficiente o del reimpiego di operatori sanitari in servizi collegati alla risposta COVID-19, ad esempio l’uso di strutture per la salute mentale come strutture di quarantena o di trattamento per il virus oppure la fornitura insufficiente dei dispositivi di protezione individuale.Occorre poi sottolineare che i Paesi ricchi, che rappresentano il 13% della popolazione mondiale, si sono accaparrati già più di 2 miliardi di dosi dei futuri vaccini, mentre l’accesso a questi ultimi sembra essere tutt’altro che vicino per i cittadini del sud globale. Un rischio reso possibile dal ‘TRIPS’, il trattato su Trade Related Aspects of Intellectual Property Rights, vale a dire il trattato internazionale che regola i brevetti e la proprietà intellettuale e che potrebbe rendere ‘privata’ la proprietà dei vaccini COVID19 che verranno prodotti, anche grazie alle ingenti risorse messe a disposizione dal settore pubblico. Non c’è dubbio che il regime di proprietà intellettuale abbia già provocato danni gravissimi sia ai paesi più poveri, come nel caso di patologie come HIV/AIDS, malaria, polmonite, ma anche nei paesi più ricchi. In Italia, ad esempio, il sistema sanitario è costretto a spendere cifre esorbitanti per rendere disponibile, a chi ne ha bisogno, la nuova terapia contro l’epatite C. Esiste un’iniziativa in India e Sudafrica per ottenere una deroga ai diritti di proprietà intellettuale in riferimento a farmaci, vaccini, mezzi diagnostici, dispositivi di protezione personale e tutte le tecnologie necessarie a fare fronte alla pandemia. È una proposta ragionevole che ha il sostegno di molti paesi, di organizzazioni internazionali, di personalità ed esperti, e anche da parte dalla Santa Sede.Lo stesso Papa Francesco ha esortato nei mesi scorsi a “globalizzare la cura, cioè la possibilità di accesso a quei farmaci che potrebbero salvare tante vite per tutte le popolazioni”, sottolineando che “per fare questo c’è bisogno di uno sforzo comune, di una convergenza che coinvolga tutti.” La barca dell’Umanità sarà in grado di far questo? Una risposta dobbiamo cercarla tutti insieme, altrimenti non c’è futuro.

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Tra medici, medicine, palliativi ed espedienti vari

Posted by fidest press agency su domenica, 6 settembre 2020

Per condurre una vita sana non dobbiamo dimenticare che molto dipende dal nostro stile di vita a partire dalla cura del corpo e dai cibi che ingeriamo e le reazioni che essi possono provocare una volta digeriti, assorbiti e metabolizzati. Più in generale possiamo dire che esiste un rapporto profondo tra le più intime strutture, che ci hanno generato, e le varie interazioni con gli elementi della natura che vi ruotano attorno in varie forme e il genere di rapporti che vi instauriamo. È anche un naturale aggregato alla “medicina dello spirito”. Dagli alchimisti ai moderni laboratori di ricerca, dagli stregoni agli stessi rituali religiosi, dagli esperti di fitofarmaci e quanto altro, ci imbattiamo in un proliferare di “pozioni” medicamentose volte a lenire la sofferenza a debellare un male e persino a procurarci qualche danno in più. Cominciamo a chiederci ciò che ci procura più disagi a partire da un’alimentazione sregolata che ci fa eccedere per un certo tipo di nutrimento e meno in altri, per un modo di vivere che ci costringe a mangiare di “volata” un panino nel bar sotto l’ufficio ecc.
Le conseguenze possono essere le più varie e non è detto che il rapporto è matematico ed è espresso in tempo reale tra causa ed effetto. Talvolta il danno che ci procuriamo con un’alimentazione congiunta a un modo di vivere dissennato, può venire dopo mesi ed anche anni e nel frattempo ci illudiamo di credere alla nostra “inossidabilità”: mangiamo di tutto, beviamo di tutto, facciamo follie e il nostro organismo sembra non risentirne. Ma su tutto è necessario assumere una consapevolezza. Il corpo umano è una struttura complessa. E proprio per questo non possiamo affidarci al caso in specie per chi predilige i “si dice” delle solite “comari” che, con molta disinvoltura e per qualsiasi acciacco, si improvvisano terapeute e specialiste in medicina.
Va inoltre posta molta attenzione per le scienze e le discipline tradizionali dell’India e della Cina, sull’uso delle piante medicinali e sulle pratiche fisiche, l’agopuntura, la pranoterapia ecc. Non dubito della loro efficacia, per il trattamento di determinate malattie, ma va, tuttavia, non trascurato il fatto importante che non sempre chi le prescrive è all’altezza della situazione. Proprio per evitare questa incompetenza terapeutica l’Unione Induista Italiana ha istituito un centro di cultura indiana per offrire la possibilità di studiare le scienze e le discipline tradizionali dell’India, tra cui Ayurveda, Yoga, Jyotisa (astrologia), Sanscrito, Danza e Canto. Hanno, in proposito, avviato degli appositi corsi, della durata di un anno, e ai partecipanti meritevoli è rilasciato un attestato di frequenza. Seguono poi i corsi d’aggiornamento. L’iniziativa è volta a dare una preparazione base che consente di impiegare quest’antica scienza come terapia naturopatica alternativa di prevenzione e cura della salute. I docenti sono tutti medici e specialisti ayurvedici provenienti dagli U.S.A. e dall’India. Questa esperienza, come molte altre, mi fa meglio comprendere il rapporto esistente tra i prodotti della natura e la loro capacità, assumendoli in determinate dosi, e per produrre sul nostro organismo determinati effetti. Lo stesso si può dire per la terapia fisica e quanto altro. (Riccardo Alfonso)

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COVID-19: EU must step up efforts to tackle medicine shortages

Posted by fidest press agency su sabato, 18 luglio 2020

The Environment, Public Health and Food Safety Committee calls for more EU self- sufficiency and better-coordinated strategies to tackle medicine shortages.In a report on the shortage of medicines, adopted by 79 votes to 1 and 0 abstentions, the Environment, Public Health and Food Safety Committee addresses the root causes of medicines shortages. It stresses the need for an increased EU response, as the problem has been exacerbated by the COVID-19 health crisis across Europe with a direct negative impact on patients’ health, safety and the continuation of their treatment.The report asks the Commission to use the upcoming pharmaceutical strategy to address the issue of availability, accessibility and affordability of safe medicines in Europe.In the approved text, MEPs call on the Commission to find ways to restore pharmaceutical manufacturing in Europe, giving priority to essential and strategic medicines as currently 40% of medicines marketed in the EU originate in non-EU countries, while 60 – 80% of active pharmaceutical ingredients are produced in China and India.
MEPs encourage the introduction of financial incentives, in line with state aid rules, to persuade producers to make active pharmaceutical ingredients and medicines in Europe. They also welcome the new EU health programme EU4Health to make medicines and medical equipment more available and more accessible.The report calls for member states to share best practices in stock management and create coordinated health strategies, including further use of joint EU procurement of medicines. It also calls on the Commission to create a European contingency reserve of medicines of strategic importance, along the lines of the RescEU mechanism. It should function as “an emergency European pharmacy” in order to minimise shortages. Equal access for all member states should be ensured through a new mechanism of just distribution.To make medicines circulate more easily between EU countries, they also want more flexible rules on packaging formats, reuse procedures, longer expiry periods and the use of veterinary medicinal products.

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Tra medici, medicine, palliativi ed espedienti vari

Posted by fidest press agency su mercoledì, 22 aprile 2020

Per condurre una vita sana non dobbiamo dimenticare che molto dipende dal nostro stile di vita a partire dalla cura del corpo e dai cibi che ingeriamo e le reazioni che essi possono provocare una volta digeriti, assorbiti e metabolizzati. Più in generale possiamo dire che esiste un rapporto profondo tra le più intime strutture, che ci hanno generato, e le varie interazioni con gli elementi della natura che vi ruotano attorno in varie forme e il genere di rapporti che vi instauriamo. È anche un naturale aggregato alla “medicina dello spirito”. Dagli alchimisti ai moderni laboratori di ricerca, dagli stregoni agli stessi rituali religiosi, dagli esperti di fitofarmaci e quanto altro, ci imbattiamo in un proliferare di “pozioni” medicamentose volte a lenire la sofferenza a debellare un male e persino a procurarci qualche danno in più.
Cominciamo a chiederci ciò che ci procura più disagi a partire da un’alimentazione sregolata che ci fa eccedere per un certo tipo di nutrimento e meno in altri, per un modo di vivere che ci costringe a mangiare di “volata” un panino nel bar sotto l’ufficio ecc.
Le conseguenze possono essere le più varie e non è detto che il rapporto è matematico ed è espresso in tempo reale tra causa ed effetto. Talvolta il danno che ci procuriamo con un’alimentazione congiunta a un modo di vivere dissennato, può venire dopo mesi ed anche anni e nel frattempo ci illudiamo di credere alla nostra “inossidabilità”: mangiamo di tutto, beviamo di tutto, facciamo follie e il nostro organismo sembra non risentirne. Ma su tutto è necessario assumere una consapevolezza. Il corpo umano è una struttura complessa. E proprio per questo non possiamo affidarci al caso in specie per chi predilige i “si dice” delle solite “comari” che, con molta disinvoltura e per qualsiasi acciacco, si improvvisano terapeute e specialiste in medicina.
Va inoltre posta molta attenzione per le scienze e le discipline tradizionali dell’India e della Cina, sull’uso delle piante medicinali e sulle pratiche fisiche, l’agopuntura, la pranoterapia ecc. Non dubito della loro efficacia, per il trattamento di determinate malattie, ma va, tuttavia, non trascurato il fatto importante che non sempre chi le prescrive è all’altezza della situazione. Proprio per evitare questa incompetenza terapeutica l’Unione Induista Italiana ha istituito un centro di cultura indiana per offrire la possibilità di studiare le scienze e le discipline tradizionali dell’India, tra cui Ayurveda, Yoga, Jyotisa (astrologia), Sanscrito, Danza e Canto. Hanno, in proposito, avviato degli appositi corsi, della durata di un anno, e ai partecipanti meritevoli è rilasciato un attestato di frequenza. Seguono poi i corsi d’aggiornamento. L’iniziativa è volta a dare una preparazione base che consente di impiegare quest’antica scienza come terapia naturopatica alternativa di prevenzione e cura della salute. I docenti sono tutti medici e specialisti ayurvedici provenienti dagli U.S.A. e dall’India. Questa esperienza, come molte altre, mi fa meglio comprendere il rapporto esistente tra i prodotti della natura e la loro capacità, assumendoli in determinate dosi, e per produrre sul nostro organismo determinati effetti. Lo stesso si può dire per la terapia fisica e quanto altro. (Riccardo Alfonso)

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Roma: Car-sharing gratuiti ai medici

Posted by fidest press agency su martedì, 24 marzo 2020

Roma. “Ringraziamo la sindaca di Roma, Virginia Raggi, per aver accolto il nostro appello sulla difficolta’ da parte del personale sanitario, impegnato in questa emergenza, che non ha mezzi propri per tornare nella propria abitazione. Bene quindi il Car sharing gratuito per i medici, che va a superare il problema della chiusura dei servizi pubblici dopo le 21”. È il commento rilasciato all’agenzia Dire dal presidente dell’Ordine dei Medici di Roma, Antonio Magi, interpellato in merito alla delibera approvata dal Comune di Roma che mette a disposizione, gratuitamente, 100 auto del Car sharing ai medici capitolini.
Le auto saranno a disposizione, da oggi fino al 3 aprile, per gli operatori sanitari impegnati in particolare nel contrasto dell’epidemia di Coronavirus, quindi di chi lavora negli ospedali Covid e nei reparti di Terapia intensiva.
“Auspichiamo ora di aprire un tavolo di lavoro con il Comune di Roma – prosegue Magi – che segua gli sviluppi dell’epidemia nella Capitale e che abbia come obiettivo quello di monitorare, oltre ai Covid Hospital, anche le altre strutture sanitarie che ospitano i malati senza Coronavirus, che sono la maggioranza – conclude – e che devono essere seguiti”.

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O. Roep, Ph.D., Advances Personalized Medicine for Children With Type 1 Diabetes

Posted by fidest press agency su martedì, 26 novembre 2019

As science continues to advance understanding how diseases like cancer and diabetes operate in the human body, the models for treatment have increasingly moved away from one-size-fits-all approaches and toward more individualized therapies.Led by Bart O. Roep, Ph.D., the Chan Soon-Shiong Shapiro Distinguished Chair in Diabetes at City of Hope and director of The Wanek Family Project for Type 1 Diabetes, a new study characterizes how immune responses to type 1 diabetes (T1D) differ among individuals much more than previously thought. The study characterizes those differences in children with T1D, which represents an important first step toward personalized medicine for this patient population.Published in Diabetologia, the journal of the European Association for the Study of Diabetes, Roep and his colleagues found that children with T1D do differ in their islet autoimmune signatures, or how they respond to immune intervention therapies. But rather than many shades of grey, they only saw three subgroups: children who respond to all islet proteins, those who respond to none, and those who only responding to two or three proteins.T1D results from the destruction of insulin-making beta cells by the body’s own immune system. Treatments rely on protecting cells called islets — which contain the insulin producing beta cells — from inflammatory attacks, but immune responses vary.Collectively, the data provided by the study give new insights into type 1 diabetes disease heterogeneity, or complexity, and highlights the importance of grouping patients on the basis of their genetic and autoimmune signatures for immunotherapy and personalized disease management.

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Stanford School of Medicine’s Carla Pugh to Keynote Healthcare Robotics Engineering Forum

Posted by fidest press agency su sabato, 16 novembre 2019

Business-to-Business publisher WTWH Media announced that Carla Pugh, Professor of Surgery and Director of the Technology Enabled Clinical Improvement (T.E.C.I.) Center at Stanford University School of Medicine, will deliver a keynote address at the 2019 Healthcare Robotics Engineering Forum. The Healthcare Robotics Engineering Forum, which takes place December 9-10, 2019 at the Santa Clara Convention Center, Santa Clara, CA, is a conference and expo focused on easing, speeding and improving the design, development and manufacture of healthcare robotics products and services.According to Dan Kara, Vice President, Robotics at WTWH Media, “We are delighted to have Carla Pugh deliver a keynote session at the Healthcare Robotics Engineering Forum. Carla is well known and very respected within the global medical community for her leadership role in advocating data driven practices, as well as the use of sensors, simulation and other advanced technologies, to improve surgical procedures and clinical outcomes. She is perfectly positioned to reveal to Healthcare Robotics Engineering Forum attendees how these same technologies can improve other classes of healthcare solutions, including robotics systems.” Carla Pugh said, “The Healthcare Robotics Engineering Forum provides an excellent opportunity to address those developing the next generation of healthcare robotics systems. I look forward to keynoting the event and discussing the ways sensors, haptics, simulation, machine learning and more can be utilized to increase capabilities and improve functionality of their solutions.”

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41st International Engineering in Medicine and Biology Conference

Posted by fidest press agency su mercoledì, 24 luglio 2019

Novocure (NASDAQ: NVCR) today announced 10 oral presentations and a special session on Tumor Treating Fields at the 41st International Engineering in Medicine and Biology (EMB) Conference, July 23 through July 27, in Berlin. The volume of Tumor Treating Fields presentations marks a record number of abstracts for Novocure at this conference.
The conference, hosted by the IEEE Engineering in Medicine and Biology Society (EMBS) will focus on the theme, “Biomedical engineering ranging from wellness to intensive care.” During an innovative and interactive special session on Tumor Treating Fields, a neurosurgeon, a radiologist, two biomedical engineers who have worked on novel solutions to treat brain cancer, and a glioblastoma patient will discuss the treatment process, evaluating candidate therapeutic technologies. The oral presentations will describe studies utilizing numerical simulations to better understand Tumor Treating Fields distribution within the body and how Tumor Treating Fields interact with cells. These studies are setting the foundation for optimizing Tumor Treating Fields dosimetry in treatment planning. “The EMB Conference showcases the latest technologies, innovations and applications to human health and well-being and provides a roadmap for the future,” said Dr. Uri Weinberg, Novocure’s Vice President of Clinical Development. “We are pleased that the focus on Tumor Treating Fields continues to expand at this conference. We look forward to participating in this important scientific exchange and exposing the biomedical engineering community to the science of Tumor Treating Fields therapy.”

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BioGENEius Challenge Announces 2019 BioGENEius Hall of Fame Awardee

Posted by fidest press agency su martedì, 4 giugno 2019

The Biotechnology Institute announced the winner of the BioGENEius Hall of Fame Award, who will be recognized next week at the 2019 BIO International Convention in Philadelphia. Each year, the Biotechnology Institute honors a past BioGENEius who best exemplifies the goals of its mission. This year we honor Michael Duong, a medical student and science advocate at the Perelman School of Medicine at the University of Pennsylvania.
Duong’s interest in science began in his childhood, creating his own “basement laboratory” complete with incubators and centrifuges. He accelerated his scientific explorations in high school with a student internship at Kibow Biotech. His passion for science led him to years of independent research and science fairs, culminating in the 2014 and 2015 International BioGENEius Challenge, the 2017 Goldwater Scholarship in Life Sciences and the 2019 Marc S. Levine Radiology Research Prize. Duong has also received honors from the US Surgeon General, House of Representatives, Department of Education and Department of Agriculture, as well as National Merit/AP scholarships.Duong’s aim is to become a physician, scientist and educator at the forefront of improving diagnosis and management of Alzheimer’s Disease.His current research focuses on applying machine learning and artificial intelligence to improve diagnosis of brain diseases and harnessing non-invasive neuroimaging biomarkers to demystify dementia progression. Michael hopes to streamline diagnosis and provide a platform for healthcare providers and the biotech industry to improve communication and discovery.As a Vietnamese American, son of refugees and family caregiver, Duong is shaped by ancestral, cultural and religious heritage. From listening to the story of his mother’s harrowing trip across the South China Sea on a wooden boat, he learned gratitude and perseverance. From caring for his grandfather with dementia, he learned compassion and patience. Duong applies these lessons of humanity and peace to his approach to molecular and computational neuroscience. By investigating Alzheimer’s disease progression in different populations, he hopes to develop tools and treatments to empower personalized care for patients. As dementia prevalence is rising substantially in developing nations like Vietnam, Michael realizes that biomedical science must be diverse and provide precision management and treatments that are unique for each population and person. Leveraging heritage and life lessons, Michael embraces the love of – and duty to – his ancestors to help cognitively impaired patients and their families.

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87th European Atherosclerosis Society Congress

Posted by fidest press agency su mercoledì, 29 Maggio 2019

The Medicines Company (NASDAQ: MDCO) today announced presentation of analyses of two clinical studies of inclisiran at the 87th European Atherosclerosis Society (EAS) Congress in Maastricht, Netherlands. A combined analysis (N=279) from the Phase 2 ORION-1 and Phase 1 ORION-7 trials, presented during an e-poster session, demonstrated that patients across a range of renal function levels achieved consistent reductions in low-density lipoprotein cholesterol (LDL-C) with no dose adjustment necessary for patients with renal impairment. Results from the Phase 2 ORION-2 pilot study, presented as a late-breaking abstract, showed that inclisiran provided durable reductions in LDL-C levels up to day 180 in patients with homozygous familial hypercholesterolemia (HoFH), a genetic disorder characterized by very high levels of LDL-C and early onset of cardiovascular disease, without the need to increase the dose of inclisiran.“The information discussed at EAS supports inclisiran’s potential to address the high burden of cardiovascular disease caused by cumulative exposure to elevated LDL-C,” said Peter Wijngaard, Ph.D., Chief Development Officer of The Medicines Company. “We are pleased with these findings that demonstrate inclisiran’s potent, durable and consistent lowering of LDL-C, as well as favorable tolerability and safety, in patients with renal insufficiency or HoFH.”Inclisiran, the first cholesterol-lowering therapy in the siRNA class, is The Medicines Company’s investigational therapy in Phase 3 clinical development to evaluate its ability to lower LDL-C through twice-a-year dosing. The company expects pivotal Phase 3 data readouts for inclisiran in the third quarter of 2019 followed by anticipated regulatory filings in the U.S. in the fourth quarter of 2019 and in Europe in the first quarter of 2020.“There remains significant unmet need in the treatment of ASCVD, as approximately four out of five statin-treated patients are not at LDL-C goals, with poor adherence to therapy a major underlying cause,” said Mark Timney, Chief Executive Officer of The Medicines Company. “We are excited at the prospect of bringing forward a revolutionary approach to treat cardiovascular disease using a twice-a-year therapy with unique potential to address the need for additional LDL-C lowering and long-standing medication adherence challenges faced by millions of people.”

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Ross University School of Medicine (RUSM) today celebrated its ceremony at the Watsco Center

Posted by fidest press agency su lunedì, 20 Maggio 2019

Coral Gables, FloridaVivian W. Pinn, M.D., was the keynote speaker. She was the inaugural full-time director of the Office of Research on Women’s Health at the National Institutes of Health (NIH) beginning in 1991 and associate director of NIH for Women’s Health Research from 1994 until her retirement in 2011.“We are honored to have such a distinguished physician, scientist and researcher as our commencement speaker,” said William F. Owen, Jr., M.D., FACP, dean and chancellor of RUSM. “Over the course of her long career, Dr. Pinn has consistently led the advancement of women’s health research, as well as developed career pathways and opportunities for women in medicine and science. Her own journey through the segregated schools of Lynchburg, Virginia, to earning her M.D. as the only woman and minority in her class at the University of Virginia School of Medicine, to becoming a world-renowned biomedical researcher is truly inspirational. She is an example to our graduates about the many opportunities that lie ahead.”Dr. Pinn led the implementation of NIH’s research inclusion policies and developed the national strategic plan for women’s health research. She established many new research funding initiatives and career development programs in collaboration with the NIH Institutes and Centers. During that time, she also established the NIH Committee on Women in Biomedical Careers with the NIH Director. Following her retirement, Dr. Pinn was named as a senior scientist emerita at the NIH Fogarty International Center.“I welcomed the opportunity to be the keynote speaker for Ross University School of Medicine, and to address this diverse group of future physician leaders,” said Dr. Pinn. “RUSM has a strong record of quality academics and over 14,000 alumni who serve their patients and communities with passion and commitment.” Dr. Pinn has held leadership positions in many professional organizations, including as the 88th president of the National Medical Association (NMA) and is currently chair of the NMA Past Presidents Council. She serves on the Board of Trustees/Advisors of Thomas Jefferson University, the Sidney Kimmel Cancer Center at Jefferson, and Tufts University School of Medicine. She is also a fellow of the American Academy of Arts and Sciences and was elected to the National Academy of Medicine in 1995.

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Modernizing Medicine Gastroenterology

Posted by fidest press agency su sabato, 18 Maggio 2019

Specialty-specific healthcare information technology leader Modernizing Medicine® Gastroenterology, formerly gMed®, announced a bi-directional clinical lab connection within the company’s gastro-specific suite of solutions, gGastro®, through its collaboration with Change Healthcare. During the annual Digestive Disease Week® (DDW) taking place in San Diego, Calif., from May 18 – 21, 2019, the new capability will be highlighted at Modernizing Medicine Gastroenterology’s booth #1142.Change Healthcare’s Exchange Orders and Results solution allows physicians to electronically submit clinical lab orders from within gGastro, as well as receive the results directly from connected labs. The streamlined workflow provides Modernizing Medicine customers with a more efficient way to communicate with laboratories, hospitals, and physician practices, and helps providers to seamlessly process and bill orders.
The company will also showcase its enhanced gGastro® Mobile EHR app solution. Compatible with iOS and Android, gGastro Mobile allows providers to access schedules, view upcoming procedures, review medication history, patient data and more right from their smartphone. The new tasking feature gives providers access to easily reply, view and complete tasks from the convenience of their phone, and they can now sign into the app with biometric verification.”Our physicians have greatly benefited from the convenience and flexibility that gGastro Mobile offers. One of our physicians was working from home when his internet went out. By using the mobile EHR, he was able to easily access his patients’ records via the app and avoided the 30-minute drive back to the office,” shared Tasha Cieslak*, practice manager at The Gastro Clinic.

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The curative use of stem cells in regenerative medicine

Posted by fidest press agency su venerdì, 10 Maggio 2019

Semma Therapeutics, Inc., a biotechnology company pioneering the curative use of stem cells in regenerative medicine, today announced the journal Nature published data demonstrating improvements in the production of beta cells (cells that produce insulin) from stem cells. Led by Harvard University researchers in collaboration with scientists from Semma, the study characterized the types of cells produced by the applicable cell differentiation methods, and demonstrated biological and physical separation methods to increase the purity of beta cells in a sample of converted stem cells from 30 to 80 percent.“The implications of these findings could be tremendously important in developing effective therapies for the more than 1.25 million people living with Type 1 diabetes in the U.S.,” said Bastiano Sanna, Ph.D., Chief Executive Officer of Semma Therapeutics. “We are immensely grateful to our collaborators at Harvard University, including Prof. Doug Melton, whose lab showed for the first time in 2014 that stem cells could be converted to functional beta cells, and who led the research presented in this important manuscript. These findings provide a solid foundation to continue to advance Semma’s mission to develop and provide best-in-class islet cell therapies for patients.”Published results summarize the single-cell sequencing and molecular biology used to identify genes expressed by each cell and the classification of those cells based on expression patterns. The paper also details the discovery of a protein expressed uniquely by beta cells, which was used to “fish” beta cells from the mixture, as well as a physical enrichment method developed by Semma scientists, which together were able to improve the purity of beta cells by more than two-fold.The manuscript, titled “Charting cellular identity during human in vitro β-cell differentiation,” may be found here. A press release issued by Harvard University describes the scientific findings in brief.

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Announces Latest Institute for Value-Based Medicine® Meeting

Posted by fidest press agency su sabato, 23 marzo 2019

The American Journal of Managed Care® (AJMC®), the leading peer-reviewed journal dedicated to issues in managed care, will host a regional Institute for Value-Based Medicine® meeting on advances in treatment and management to reduce the costs and improve the outcomes of patients with diabetes. The meeting will take place Wednesday, April 17, 6-9 p.m., at Loews Santa Monica Beach Hotel in California and will be chaired and moderated by Peter C. Butler, M.D., professor of medicine, endocrinology, diabetes and hypertension, David Geffen School of Medicine, and director of the Larry L. Hillblom Islet Research Center at the University of California, Los Angeles (UCLA).“We look forward to presenting our latest meeting on diabetes treatment and management,” said Michael J. Hennessy Jr., president of MJH Associates, Inc., parent company of AJMC®. “Attendees who participate in this live educational program will gain expert insight into best practices in diabetes value-based care from leading health systems, receive practical guidance on implementation of patient-centric care and will learn about innovative models for diabetes treatment and management.”

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Samsung Bioepis’ First Oncology Medicine in the United States

Posted by fidest press agency su mercoledì, 23 gennaio 2019

Samsung Bioepis Co., Ltd. today announced that the U.S. Food and Drug Administration (FDA) has approved ONTRUZANT® (trastuzumab-dttb), a biosimilar referencing HERCEPTIN® 1 (trastuzumab), across all eligible indications, namely adjuvant treatment of HER2-overexpressing breast cancer, metastatic breast cancer and metastatic gastric cancer or gastroesophageal junction adenocarcinoma in patients who have not received prior treatment for metastatic disease. Please see Boxed Warnings and Important Safety Information for ONTRUZANT® below.
ONTRUZANT® is Samsung Bioepis’ first oncology biosimilar to receive FDA approval, and will be marketed and distributed in the United States (US) by Merck, which is known as MSD outside of the US and Canada.“For many cancer patients in the US, battling cancer has not only been a health issue, but a considerable financial burden brought on by cancer treatment. Biosimilars are intended to be lower cost, high-quality treatment options that have the potential to alleviate such burden. We sincerely hope our trastuzumab biosimilar will do exactly that,” said Sang-Jin Pak, Senior Vice President and Head of Commercial Division, Samsung Bioepis. “At Samsung Bioepis, we will continue to demonstrate our enduring commitment to biosimilars by further strengthening our pipeline and widening the availability of approved treatments for cancer patients across the US.” ONTRUZANT® was also approved by the European Commission (EC) in November 2017, and has since been launched in a growing number of European countries.

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SanBio: Addition of a Cerebral Hemorrhage Program for SB623 Regenerative Cell Medicine

Posted by fidest press agency su mercoledì, 23 gennaio 2019

At a meeting held today, the Board of Directors of SanBio Co., Ltd. (hereinafter, the “Company”) resolved to add a program for treatment of chronic motor deficit from cerebral hemorrhage as a new indication for SB623, a regenerative cell medicine developed by the Group. (Hereinafter, the “Group” refers to two companies, SanBio Co., Ltd., and SanBio, Inc.) As part of its mission to introduce new therapeutic drugs for the central nervous system, the Group is moving forward with the development of programs for chronic motor deficit from traumatic brain injury (TBI) and chronic motor deficit from ischemic stroke, centering on the United States and Japan. Regarding the program for treatment of chronic motor deficit from TBI, positive results were announced on November 1, 2018, with respect to a Phase 2 clinical trial, namely that “Patients administered SB623 demonstrated a statistically significant improvement in their motor function compared to the control group, confirming that the study has met its primary endpoint.” Regarding the program targeting chronic motor deficit from ischemic stroke, the Company expects to announce results of a Phase 2b clinical trial in the first half of the fiscal year ending January 31, 2020 (from February 1, 2019 to July 31, 2019).Given the positive results of the program targeting chronic motor deficit from TBI mentioned above, the Group has reevaluated the scope of indications for SB623. Consequently, the Company has decided to initiate a program for treatment of chronic motor deficit from cerebral hemorrhage, which is similar to TBI, as a new indication for SB623. The Company is considering Japan and the United States as development regions for this program.
Ischemic stroke is caused by the blockage of blood vessels, whereas cerebral hemorrhage results from ruptured blood vessels. Both can result in hemiplegia, sensory impairment, or memory impairment. Currently, no definitive therapy exists.As of today, the Company expects to commence clinical trials for this program from Phase 2 or Phase 3. However, the development details and timing are not yet decided. The Company will provide these as soon as they become available.
This decision does not affect the Company’s consolidated operating performance for the fiscal year ending January 31, 2019.

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2° Congresso internazionale della European Alliance for Personalised Medicine

Posted by fidest press agency su venerdì, 16 novembre 2018

Milano mercoledi 28 novembre ore 13.00 Sala 39 (Piano 39°), Palazzo Regione Lombardia,
Piazza Città di Lombardia 1, 2° Congresso internazionale della European Alliance for Personalised Medicine. Alla presentazione del progetto Europeo “Regions4Permed” saranno presenti rappresentanti della Commissione Europea, della EAPM e delle realtà italiane coinvolte: Toscana Life Sciences per la Regione Toscana e Fondazione Regionale per la Ricerca Biomedica per la Regione Lombardia.

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Adtalem Global Education Announces Barbados as New Location for Ross University School of Medicine

Posted by fidest press agency su lunedì, 6 agosto 2018

Adtalem Global Education (NYSE: ATGE), a leading global education provider, today announced it is relocating Ross University School of Medicine (RUSM)’s medical sciences campus to Barbados. The academic center will be in Bridgetown, leveraging existing facilities centrally located in the vibrant capital city. Student housing will be located in the parish of Christ Church at an existing housing community that includes access to a community center, shopping, day care, student services and transportation to campus. Students will begin the January 2019 semester at the new location, pending final regulatory approval from the U.S. Department of Education.
Prime Minister Mottley, in welcoming Ross University to Barbados, said, “This is the type of investment that is very important to the advancement of the Barbadian economy, and which will also add immeasurably to our diversity. I am confident that this prestigious university campus will impact significantly on the Barbadian landscape on many levels. We are committed to transforming Barbados into a hub for educational and medical services, including educational and medical tourism. We recognise that these areas of tourism are among the fastest growing areas in travel and tourism worldwide. This venture will be an important pillar in that mission. We are very proud of our infrastructure and expect RUSM students and faculty to settle very quickly within our community, benefitting not only academically but also from the rich cultural experiences that they will have while living here.”
Founded in 1978, RUSM is a significant contributor to the U.S. medical workforce. RUSM’s 14,000 diverse alumni practice medicine throughout North America and across all specialties, including a high percentage of graduates who enter the in-demand field of primary care. In September of 2017, Dominica was severely damaged by Hurricane Maria, causing devastation to the island, its buildings and infrastructure, and leading to the safe evacuation of our students and faculty. Since that time, the institution has maintained the quality and continuity of its medical education program at temporary locations while damage assessment, repair and rebuilding has occurred on the Dominica campus.Adtalem is very mindful of the people of Dominica and the needs of the community, and is creating a plan in close coordination with Prime Minister Roosevelt Skerrit and the government of Dominica that will take these matters into meaningful consideration, including an appropriate transition of our campus property and buildings. Furthermore, Adtalem is committed to providing support to colleagues during the transition.

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