Fidest – Agenzia giornalistica/press agency

Quotidiano di informazione – Anno 31 n°159

Posts Tagged ‘meeting’

Altai Capital Responds to Amber Road’s Postponement of Annual Meeting

Posted by fidest press agency su sabato, 20 aprile 2019

Altai Capital Management, L.P. (“Altai Capital”), one of the largest shareholders of Amber Road, Inc. (NYSE: AMBR) (“Amber Road” or, the “Company”), today issued the following statement regarding the Company’s sudden announcement that it will postpone the 2019 Annual Meeting of Stockholders (the “Annual Meeting”), which was originally scheduled for May 7, 2019, by more than a month to June 18, 2019.“The unexplained decision of Amber Road’s Board to postpone the Annual Meeting appears to us to be a clear attempt to further entrench the Board and avoid accountability. We believe investors deserve the opportunity to voice, without delay, their frustration at the strategic missteps of the Company’s leadership. By delaying the shareholders’ right to elect directors at the appropriate meeting time, we believe the Company is perpetuating the pattern of self-serving actions and value destruction that have characterized Amber Road to date. We see no valid purpose for postponing the Annual Meeting and question the Board’s decision to do so only days before the scheduled date and after proxies have already been delivered to shareholders. In the absence of any explanation, we can only conclude that the Board is trying to buy more time to gather support they do not believe they have. As we have stated all along, Amber Road’s Board is in critical need of improvement—fresh, independent minds are essential to hold management accountable, to properly explore strategic alternatives and to provide shareholders with the transparency they deserve. This Board’s delay tactics only reinforce our concerns, serving as an acute reminder that the Company’s current Board, in our view, prioritizes its desire to stay in office over respecting the rights of its shareholders. To the extent that the current Board is deliberating on material decisions, we strongly believe that such deliberations should be conducted by a new, duly elected Board best-positioned to represent the best interests of all shareholders.

Posted in Estero/world news | Contrassegnato da tag: , , | Leave a Comment »

Arcos Dorados to Host the Annual General Shareholders’ Meeting

Posted by fidest press agency su mercoledì, 27 marzo 2019

Arcos Dorados Holdings Inc. (NYSE:ARCO) (“Arcos Dorados” or the “Company”), Latin America’s largest restaurant chain and the world’s largest independent McDonald’s franchisee, today announced that on March 22, 2019, the Board of Directors set the date for the Company’s Annual Shareholders’ Meeting (“AGM”). The AGM will be held on April 22, 2019, in Montevideo, Uruguay, at 10:00 a.m. (local time), for all shareholders of record as of April 2, 2019.
Arcos Dorados is the world’s largest independent McDonald’s franchisee in terms of systemwide sales and number of restaurants, operating the largest quick service restaurant chain in Latin America and the Caribbean. It has the exclusive right to own, operate and grant franchises of McDonald’s restaurants in 20 Latin American and Caribbean countries and territories, including Argentina, Aruba, Brazil, Chile, Colombia, Costa Rica, Curaçao, Ecuador, French Guyana, Guadeloupe, Martinique, Mexico, Panama, Peru, Puerto Rico, St. Croix, St. Thomas, Trinidad & Tobago, Uruguay and Venezuela. The Company operates or franchises over 2,200 McDonald’s-branded restaurants with over 90,000 employees and is recognized as one of the best companies to work for in Latin America. Arcos Dorados is traded on the New York Stock Exchange (NYSE:ARCO). To learn more about the Company, please visit the Investors section of our website: http://www.arcosdorados.com/ir.

Posted in Estero/world news | Contrassegnato da tag: , , | Leave a Comment »

Announces Latest Institute for Value-Based Medicine® Meeting

Posted by fidest press agency su sabato, 23 marzo 2019

The American Journal of Managed Care® (AJMC®), the leading peer-reviewed journal dedicated to issues in managed care, will host a regional Institute for Value-Based Medicine® meeting on advances in treatment and management to reduce the costs and improve the outcomes of patients with diabetes. The meeting will take place Wednesday, April 17, 6-9 p.m., at Loews Santa Monica Beach Hotel in California and will be chaired and moderated by Peter C. Butler, M.D., professor of medicine, endocrinology, diabetes and hypertension, David Geffen School of Medicine, and director of the Larry L. Hillblom Islet Research Center at the University of California, Los Angeles (UCLA).“We look forward to presenting our latest meeting on diabetes treatment and management,” said Michael J. Hennessy Jr., president of MJH Associates, Inc., parent company of AJMC®. “Attendees who participate in this live educational program will gain expert insight into best practices in diabetes value-based care from leading health systems, receive practical guidance on implementation of patient-centric care and will learn about innovative models for diabetes treatment and management.”

Posted in Estero/world news | Contrassegnato da tag: , | Leave a Comment »

ERYTECH Presents Findings at European Red Cell Research Society Meeting

Posted by fidest press agency su venerdì, 15 marzo 2019

LYON, France and CAMBRIDGE, Mass., (GLOBE NEWSWIRE) — ERYTECH Pharma (Euronext Paris: ERYP – Nasdaq: ERYP), a clinical-stage biopharmaceutical company developing innovative therapies by encapsulating drug substances inside red blood cells, announced that an oral presentation entitled “Comprehensive proteomic profiling of erythrocytes following hypotonic dialysis-based drug encapsulation process“ will be presented today at the 22nd meeting of the European Red Cell Research Society (ERCS) in Ascona, Switzerland. A poster highlighting the results of this work will also be presented at the ERCS Meeting and will be available on the Company’s website at http://www.erytech.com after March 11, 2019.The lead investigational therapeutic produced using the Company’s ERYCAPS® encapsulation process, eryaspase, consisting of the enzyme L-asparaginase encapsulated inside donor-derived red blood cells, is currently being evaluated in the Phase 3 TRYbeCA-1 trial in metastatic pancreatic cancer. In an earlier 141 patient randomized Phase 2b trial of eryaspase in combination with chemotherapy for the treatment of second-line metastatic pancreatic cancer, significant improvements in overall survival and progression free survival were observed versus chemotherapy alone with no apparent increase in toxicity2.
The erythrocyte proteomic profiling study being presented at the meeting was performed with the participation of the 3P5 Proteomic Platform (at the Paris-Descartes University, France) specialized in high-performance mass spectrometry protein identification and microanalysis. With the exception of L-asparaginase, profiling analysis revealed no significant difference in the proteomic landscape when comparing packed RBCs, ERYCAPS®-processed RBCs without enzyme, and ERYCAPS®-processed RBCs encapsulating L-asparaginase.These results confirm the notion that the ERYCAPS® process does not significantly alter the properties of RBCs and that apart from the encapsulated drug substance, RBC-based therapeutics produced using this process have similar characteristics to that of unprocessed packed RBCs.
ERYTECH plans to advance candidates using the ERYCAPS® platform and to explore the field of RBC-based therapeutics, building on these proteomic results and future findings regarding RBC biology.

Posted in Estero/world news | Contrassegnato da tag: , , | Leave a Comment »

Allegion to Host Investor, Analyst Meeting in New York City

Posted by fidest press agency su giovedì, 21 febbraio 2019

Allegion plc (NYSE:ALLE), a leading global security products and solutions provider, will hold an Investor and Analyst Meeting in New York City on Tuesday, March 12, 2019, from 11:30 a.m. to 5 p.m. ET. David D. Petratis, chairman, president and CEO, will lead the meeting. He will be joined by Allegion’s executive leadership team to discuss the company’s strategy and vision for the future.Formal presentations will begin at 12:30 p.m. ET, and a real-time, listen-only webcast of the meeting will be broadcast live over the Internet. To listen, individuals can access the meeting through Allegion’s website at http://investor.allegion.com/. For those unable to listen to the live event, a replay will also be available on Allegion’s website beginning Thursday, March 14.
Allegion (NYSE: ALLE) is a global pioneer in safety and security, with leading brands like CISA®, Interflex®, LCN®, Schlage®, SimonsVoss® and Von Duprin®. Focusing on security around the door and adjacent areas, Allegion produces a range of solutions for homes, businesses, schools and other institutions. Allegion is a $2.7 billion company, with products sold in approximately 130 countries.

Posted in Estero/world news | Contrassegnato da tag: , , | Leave a Comment »

4rt Annual Meeting Alleanza Contro il Cancro

Posted by fidest press agency su domenica, 17 febbraio 2019

Si svolgerà dal 20 al 22 novembre prossimi nell’Aula Magna del Rettorato dell’Università Sapienza di Roma il quarto Annual Meeting di Alleanza Contro il Cancro, la Rete Oncologica Nazionale fondata dal Ministero della Salute.L’evento, dal titolo New Technologies and Strategies to Fight Cancer, è organizzato dall’Istituto Nazionale Tumori IRCCS Regina Elena, tra i soci fondatori di ACC. La tre giorni mira a coinvolgere quei ricercatori e quei clinici – che tramite la ricerca traslazionale hanno il compito di caratterizzare le alterazioni molecolari dei tumori a livello ‘omico – a scoprire nuovi biomarcatori e a disegnare protocolli terapeutici innovativi in un processo che parte dal letto del Paziente, arriva nei laboratori di ricerca e ritorna al Paziente stesso.«Un forum – è il commento degli organizzatori – per discutere tutti gli argomenti della ricerca contemporanea sui tumori umani, un percorso che potrà creare nuove opportunità e sfide per la medicina oncologica di precisione». Il meeting affronterà in particolare i seguenti temi:
– Come il genoma dei tumori guida e modifica le attuali cure oncologiche;
– Le sfide precliniche e cliniche nell’immunoterapia dei tumori;
– I temi relativi alla resistenza farmacologica che genera progressione e metastatizzazione neoplastica.
I dati raccolti condurranno ad una discussione generale al fine di comprendere se sarà possibile disegnare nuovi protocolli terapeutici per la sperimentazione clinica.

Posted in Medicina/Medicine/Health/Science | Contrassegnato da tag: , , | Leave a Comment »

IAB Annual Leadership Meeting

Posted by fidest press agency su martedì, 12 febbraio 2019

IAB commenced its 2019 Annual Leadership Meeting at the JW Marriott Phoenix Desert Ridge Resort and Spa in Phoenix, AZ, with more than 1,500 digital advertising marketing and brand executives. This year, with the largest-ever slate of speakers for the event, the annual three-days of debate, discoveries, and decisions will be centered around the theme: “The Theory of Revolution: Sparking Growth in the Direct Brand Economy,” helping publishers, brands and their partners learn how to thrive in the emerging direct brand economy where young direct-to-consumer brands can compete with the largest global brands on earth.
The biggest names in the business will spearhead these historic dialogues. Tomorrow, the conference opens with a keynote presentation from direct brand royalty: ThirdLove Co-Founders and Co-CEOs Heidi Zak and Dave Spector. Together they will share with the audience the realities of what it takes to succeed as a direct-to-consumer brand, and what the shift to direct brands means for the media and advertising industry. Monday, Brian Lesser, CEO, Xandr, who has a prescient eye for what sticks, will offer his perspective on the changing dynamics of the TV advertising business. Tuesday morning, Linda Yaccarino, Chairman, Advertising Sales and Partnerships, NBCUniversal, and Laura Correnti, Partner, Giant Spoon and Co-Host of the “Adlandia” podcast, will discuss the future of disruption in the world of premium advertising. Closing the conference with a not-to-be-missed session, Sir Martin Sorrell, Executive Chairman, S4Capital, will engage in a one-on-one discussion with Pete Kim, CEO, MightyHive about the trends they are seeing, and choosing to respond to, in their keynote entitled, “A View from the Top of the (R)evolution.”

Posted in Estero/world news | Contrassegnato da tag: , , | Leave a Comment »

The American Journal of Managed Care® Announces Latest Institute for Value-Based Medicine® VB-Onc Meeting

Posted by fidest press agency su domenica, 10 febbraio 2019

The American Journal of Managed Care (AJMC), the leading peer-reviewed journal dedicated to issues in managed care, with its Institute for Value-Based Medicine will host a regional VB-Onc™ meeting on advancing quality in oncology care in the evolving value-based care landscape. The meeting will take place Thursday, March 7, from 5:30 to 9 p.m. at the Four Seasons Resort and Club Dallas at Las Colinas in Irving, Texas. “This live educational meeting is a wonderful opportunity for healthcare professionals to engage and interact with some of the top leading experts in oncology-focused value-based care,” said Gil Hernandez, director of sales of managed markets at MJH Associates, parent company of AJMC. “We look forward to educating attendees on the evolving value-based care transformations impacting the oncology landscape today.” This meeting will feature four presenters: Ray D. Page, D.O., Ph.D., FACOI, president and director of research at The Center For Cancer and Blood Disorders, as the chairman and moderator; John V. Cox, D.O., MBA, FACP, FASCO, medical director of oncology services at Parkland Health and Hospital System, UT Southwestern Medical Center; Kashyap Patel M.D., vice president of the Community Oncology Alliance and president of Carolina Blood and Cancer Care; Barry Russo, chief executive officer of The Center For Cancer and Blood Disorders; and Lance Spivey, co-founder and president of StratiFi Health. The presenters will provide attendees with the latest insights and case studies on how to implement value-based payment models in their oncology practices; educate on best practices in care management, pharmacy management and practice transformation in our new health care landscape; and provide practical guidance on use of clinical pathways, patient management and data reporting under new quality requirements.The Institute for Value-Based Medicine offers informative regional series, such as VB-Onc, that focus on multi-stakeholder perspectives from oncologists, payers and practice executives. With a goal to discuss pressing topics, such as the implications of value-based medicine on clinical practice, best practices in implementing the Oncology Care Model and the integration of oncology clinical and financial-management perspectives with evolving value-based medicine, the program features leading experts from the field of managed care to enhance audience knowledge.

Posted in Estero/world news | Contrassegnato da tag: , | Leave a Comment »

QuintessenceLabs Attending World Economic Forum 2019 Annual Meeting

Posted by fidest press agency su lunedì, 21 gennaio 2019

The World Economic Forum Annual Meeting will run from January 22 to January 25 in Davos-Klosters, Switzerland.
Global leader in cyber security, QuintessenceLabs, today announced founder and CEO Vikram Sharma’s participation at the World Economic Forum’s 2019 Annual meeting in Davos-Klosters this week.Dr Sharma’s attendance at Davos comes off the back of QuintessenceLabs being named a 2018 World Economic Forum Technology Pioneer, in recognition of the company’s cutting-edge advances in cybersecurity and leadership in quantum innovation. QuintessenceLabs was one of a select group of companies around the world to be awarded the title of Technology Pioneer, for the design, development and deployment of technologies and innovations poised to make a significant impact on business and society.While at Davos, Dr Sharma will participate in sessions between other Technology Pioneers and senior Annual Meeting delegates and share his insights on global security risks, and the role of quantum technologies as both a cybersecurity threat and an opportunity for businesses and governments.“It was a great honour to be named a 2018 Technology Pioneer and, in turn, be invited to attend Davos with the world’s leaders and influencers across business, government, academia and the arts,” said Dr Sharma. “I’m looking forward to contributing to a dialogue about today’s critical security challenges and highlighting the technological innovations being developed in Australia, that have the potential to solve global challenges.”

Posted in Economia/Economy/finance/business/technology, Estero/world news | Contrassegnato da tag: , , | Leave a Comment »

Federal Street Acquisition Corp. to Adjourn Special Meeting of Stockholders

Posted by fidest press agency su giovedì, 20 dicembre 2018

Federal Street Acquisition Corp. (NASDAQ: FSACU, FSAC, FSACW) (“FSAC”), a special-purpose acquisition company sponsored by an affiliate of Thomas H. Lee Partners, L.P., and the holding company of Agiliti Health, Inc. (f/k/a Universal Hospital Services, Inc.) (“Agiliti Health”), a leading, nationwide provider of healthcare technology management and service solutions and a portfolio company of Irving Place Capital Management, L.P., announced today that FSAC convened and then adjourned, without conducting any business, the special meeting of FSAC stockholders held on Monday, December 17, 2018, at 10:00 a.m. Eastern Time, until Thursday, January 3, 2019, at 10:00 a.m. Eastern Time, at the offices of Thomas H. Lee Partners, L.P., 100 Federal Street, 35th Floor, Boston, Massachusetts 02110.In connection with the adjournment, FSAC is extending the deadline for holders of its Class A common stock to submit their shares for redemption to 5:00 p.m. Eastern Time on December 31, 2018.

Posted in Estero/world news | Contrassegnato da tag: , , | Leave a Comment »

Importante novità per la meeting industry europea

Posted by fidest press agency su martedì, 23 ottobre 2018

Monte Carlo. Dal 2 al 4 dicembre prossimi presso il Fairmont Monte-Carlo per iniziativa della DMC InspireME Monte-Carlo di Miek Egberts (specializzata in eventi Mice creativi e di alto profilo) e della società di consulenza Sustained Impact di Claudia van’t Hullenaar debutterà in Europa il Sustainable Event Professional Certificate (SEPC), una delle principali certificazioni green per professionisti della meeting, events & wedding industry.
Miek in particolare non è nuova alla ribalta internazionale, avendo ricevuto lo scorso maggio il Jane E. Schuldt SITE Master Motivator Award, il più grande riconoscimento mondiale riservato ai motivatori dell’industria meeting & incentive.La due-giorni di formazione, rivolta a organizzatori di eventi (corporate e di agenzia), a fornitori di spazi e servizi e a chiunque abbia interesse ad approfondire il tema della sostenibilità negli eventi, prevede seminari e prove pratiche volte a illustrare il valore degli eventi sostenibili non solo per l’impatto sull’ambiente, ma anche per la brand reputation e l’economicità (gli eventi sostenibili fanno risparmiare). Focus particolare sarà posto anche su metodi e tecniche di organizzazione sostenibile nonché sulla misurazione dell’impatto ambientale e sulle metodologie di reporting.

Posted in Economia/Economy/finance/business/technology, Estero/world news | Contrassegnato da tag: , , | Leave a Comment »

Sono-Tek Announces Results of 2018 Annual Meeting of Shareholders

Posted by fidest press agency su martedì, 28 agosto 2018

Sono-Tek Corporation (OTCQX:SOTK), the leading developer and manufacturer of ultrasonic coating systems, announced that shareholders voted in favor of the two proposals presented at the Company’s Annual Meeting of Shareholders held today:
The re-election of Eric Haskell, CPA, Dr. Donald Mowbray, and Samuel Schwartz, each to hold office for a two-year term.
The ratification of Liggett & Webb, P.A., as the Company’s auditors for fiscal year 2019 which ends February 28, 2019.
At the meeting, Company management provided an overview of Sono-Tek and the opportunities presented by market for its technology and application know-how, particularly highlighting the potential in the fuel cell market. Sono-Tek’s ultrasonic coating solution provides a more uniform and porous coating of the platinum catalyst for fuel cells that enables greater power efficiency, reduces waste of expensive materials and provides production level efficiencies for the fuel cell industry as it gains momentum. The business review presentation is available on the Company’s website at http://www.sono-tek.com/about-us/investors/events-presentations.
Stephen Harshbarger, President and Director of the Company noted, “These are very exciting times for the Company. We are broadening our addressable market by demonstrating advanced application expertise with the goal of making our customers successful.” He concluded, “Lab activity and proposals are at record levels and our conversion rate to sales is a very high percentage. Importantly, our implementation of lean practices and the automation and digitization of our production processes has measurably improved our ability to generate cash. We are very excited at Sono-Tek about the opportunities in front of us and the potential we have to measurably grow.”

Posted in Estero/world news | Contrassegnato da tag: , , | Leave a Comment »

V “Meeting nazionale giornalisti cattolici e non”

Posted by fidest press agency su domenica, 12 agosto 2018

Roma 12 settembre 2018 Il programma della giornata prevede: Ore 8.30 – Ritrovo in Piazza San Pietro ed incontro con Papa Francesco alle ore 9.
Ore 12.00 – Tempo libero per visitare la Città Eterna. Ore 15.00 – Università della Santa Croce (Piazza di Sant’Apollinare 49 – accanto a Piazza Navona), momento formativo Ore 19.00 – Conclusione.

Posted in Roma/about Rome, Spazio aperto/open space | Contrassegnato da tag: , | Leave a Comment »

SIOFA meeting adopts measures for sustainable fisheries in the South Indian Ocean

Posted by fidest press agency su sabato, 21 luglio 2018

The Fifth Meeting of the Parties of the South Indian Ocean Fisheries Agreement (SIOFA) was held from 25-29 June in Phuket, Thailand. Parties, including the European Union, achieved significant progress on many fronts that will strengthen the organisation and help ensure the sustainable use of fish stocks in the South Indian Ocean.
Following EU proposals, SIOFA for the first time designated five areas as interim protected areas. These areas have been provisionally closed to trawling, and the scientific observer coverage for trap and line fishing increased from 20% to 100%, until science-based management plans have been developed for each of them. Work will now continue to strengthen the designation process of protected areas and allow meaningful and tailor-made management plans in SIOFA protected areas to be adopted and carried out.The EU had also tabled several proposals to reinforce monitoring, control and surveillance. As a result, SIOFA decided to develop a vessel monitoring system by 2020 and to introduce entry-exit reports for all SIOFA registered vessels moving in and out of the Agreement area. In addition, the fight against illegal, unreported and unregulated (IUU) fishing was strengthened, with new provisions introducing the cross-listing of IUU vessels across regional fisheries management organisations.In a bid to strengthen SIOFA’s effectiveness, and based on a joint proposal from Australia and the EU, parties agreed to introduce a compliance monitoring scheme. This is an important step towards improving compliance with SIOFA conservation and management measures. Parties also agreed to amend the rules on data provision, making scientific observer data compulsory. This will significantly improve SIOFA’s scientific work and strengthen the scientific advice underpinning its decision-making.Finally, following an EU proposal, SIOFA adopted specific provisions for plastics disposal on board fishing vessels in accordance with the International Convention for the Prevention of Pollution from Ships, MARPOL.

Posted in Estero/world news | Contrassegnato da tag: , , | Leave a Comment »

Arte meeting in Rome

Posted by fidest press agency su venerdì, 20 luglio 2018

Roma sabato 24 luglio dalle 17 alle 19 Visitabile da lun a ven 11-19 Rossocinabro Sala A Via Raffaele Cadorna, 28 La Mostra presenta una raccolta di autori con diversi modi di espressione, che portano però ad un’unica destinazione, la sensazione della vita nel suo complesso. Autori con linguaggio contemporaneo ma che si distinguono per conoscenze che si concentrano sulla consapevolezza della grande ricchezza ereditata e hanno lavorato al fine di esaltare la loro forza creativa, poetica, inventiva, emotiva e i flussi critici inerenti alla vita di ciascuno di loro; propongono una diluizione tra Arte e Vita.
The Exhibition brings together authors with different ways of expression, leading to a single destination, the feel of life as a whole. Authors with contemporary language and differentiated themselves, of knowledge that focus on awareness of the vast inherited wealth and worked in order to enlarge each the power increasingly creative, poetic, inventive, emotional and critical flows inherent in the life of each; proposing a dilution between Art and Life. curated by Geni Settanni
Artists: Afonso, Cruz, Gariglio, Guimarães, Higa, Inês, Krug, Kwsta, Landgraff, Lima, Lúcio, Lupegoraro, Mota, Nunes, Pessutto, Guimmaraes, Scaléa, Ziegler.

Posted in Mostre - Spettacoli/Exhibitions – Theatre, Roma/about Rome | Contrassegnato da tag: , , | Leave a Comment »

Docente Unicam relatore in diversi meeting negli USA

Posted by fidest press agency su giovedì, 28 giugno 2018

Camerino. Estremamente positiva la missione negli Stati Uniti del prof. Massimo Sargolini, docente della Scuola di Architettura e Design dell’Università di Camerino. Tra la fine aprile e la prima metà di maggio, infatti, il prof. Sargolini ha tenuto in qualità di relatore ben 7 meeting in diverse Università americane, all’Ambasciata Italiana in USA e alla World Bank, con l’obiettivo di presentare il Consorzio di Ricerca “REDI – Reducing Risks of Natural Disasters”, una nuova piattaforma di ricerca interdisciplinare per la riduzione del rischio di catastrofi promossa dall’Università di Camerino in collaborazione con altre università italiane ed europee.Il prof. Sargolini ha avuto l’opportunità di illustrare ai colleghi statunitensi le gravi conseguenze del terremoto del 2016 nell’Italia centrale nonché di acquisire da loro preziose esperienze nel campo della ricerca di riduzione dei rischi naturali e di calamità; è stato inoltre possibile avviare una prima rete di università italiane e americane per poter partecipare congiuntamente alla call “Italia-Usa – Cooperazione scientifica e tecnologica”.

Posted in Cronaca/News, Università/University | Contrassegnato da tag: , , , | Leave a Comment »

Novel Non-Addictive Opioid Described at CPDD Annual Meeting in San Diego

Posted by fidest press agency su lunedì, 18 giugno 2018

A novel opioid compound that targets all three pain receptors in the brain with no addiction potential was described this week at the CPDD Annual Meeting.During the symposium “Next Generation Analgesics,” led by Dr. Nora Volkow, director of the National Institutes on Drug Abuse (NIDA), Lawrence Toll, Ph.D., co-founder and chief neuropharmacologist of Phoenix PharmaLabs, described the drug. His talk “PPL-103: A kappa partial agonist with potent antinociceptive activity and low abuse potential” focused on the promising success that has been achieved in a large number of published, as well as non-published, in vivo studies to date.
All opioids on the market today bind to the mu receptor in the brain and then aggressively stimulate that receptor. The mu receptor produces euphoria that leads to abuse and addiction. PPL-103 is a patented analog that binds strongly to all three opioid receptors in the brain (mu, kappa and delta) and then partially stimulates those receptors in a more balanced manner. This partial stimulation derives potent analgesic benefit from all three receptors, but is not sufficiently strong to produce the serious opioid side-effects associated with any single receptor. This results in a first-ever opiate analgesic that appears to be non-addicting and free of all significant dangerous side effects.

Posted in Estero/world news | Contrassegnato da tag: , , | Leave a Comment »

G7 e i nuovi equilibri geopolitici, sociali, economici e finanziari

Posted by fidest press agency su domenica, 10 giugno 2018

Il recente meeting del G7 visto con la lente d’ingrandimento dei media nazionali, per via del debutto del neo presidente del consiglio Giuseppe Conte, ci lascia perplessi sul come il tema sia stato sviluppato in quanto l’importanza dell’evento non riguardava di certo, per quanto apprezzabile, la figura del nostro presidente del consiglio ma la svolta drammatica che sta assumendo quello che si riteneva un rapporto di forza stabilizzato tra i paesi che continuano a considerarsi il Deus ex machina sulla scena mondiale. La realtà invece sembra incamminarsi su una strada diversa e non c’è peggior cieco di chi non vuole vedere. Se a questo punto consideriamo, con pragmatismo, quando sta accadendo intorno a noi dobbiamo prendere atto che è in via di consolidamento un nuovo assetto mondiale che vede all’orizzonte la comparsa di altri soggetti quali la Russia, la Cina e l’India la cui forza economica e influenza politica hanno aperto nuovi scenari appannando quelli rappresentati sino ad oggi dall’Europa comunitaria, dagli Usa dal Canada e dall’Australia. Non solo. Per quanto possa sembrare assurdo è stata proprio la globalizzazione a infliggere il colpo mortale a quella parte del mondo che si definisce “occidente”. O per meglio dire ad un modello globalizzato che rende libero lo scambio di merci e di produzioni ma senza risolvere la logica dei prezzi unitari dei prodotti che riverberano da una parte il basso costo della manodopera e delle tecnologie e dall’altra la sconsiderata risposta occidentale nella rincorsa alla riduzione o mancato adeguamento dei salari al costo della vita e delle tutele sul lavoro che, tra l’altro, limitano il potere d’acquisto e favoriscono le merci importate dai paesi dove il tenore di vita è grandemente più basso. A questo punto Trump ha il merito d’aver preso, come si suole dire, il toro per le corna e intrapreso un percorso che già da tempo avremmo dovuto imboccare. E non cerchiamo ipocritamente di scandalizzarci. Persino nei 27 paesi dell’Ue le differenze salariali provocano i trasferimenti delle aziende da un paese all’altro. Non accadrebbe se a quelle imprese, che vogliono far rientrare le merci prodotte altrove, venga imposto un dazio. E allora smettiamola al sentirci diminuiti se il nostro presidente del consiglio ha stretto una mano di meno ai cosiddetti “grandi della terra” e pensiamo a quelli che stanno diventando davvero tali come Putin, Xi Jinping e Ram Nath Kovind. Non sono nel G7 ma i loro paesi valgono molto di più sulla scena mondiale. (Riccardo Alfonso)

Posted in Confronti/Your opinions | Contrassegnato da tag: , , , | Leave a Comment »

HomeStreet Announces Preliminary Results from Annual Meeting

Posted by fidest press agency su lunedì, 28 maggio 2018

HomeStreet, Inc. (Nasdaq:HMST) (the “Company” or “HomeStreet”), the parent company of HomeStreet Bank, today announced that based on the preliminary vote count at the Company’s 2018 Annual Meeting reviewed by its proxy solicitor, all three of the Company’s director nominees, Scott M. Boggs, Douglas I. Smith and Mark R. Patterson, have been reelected to the Company’s Board of Directors. HomeStreet previously indicated that, despite the substantial risk that votes on Roaring Blue Lion’s blue proxy cards would be considered invalid under Washington State banking law, the Company would count votes on blue proxy cards on a provisional basis, subject to the final determination as to the validity of the blue proxy cards. Notably, whether or not votes on blue proxy cards are counted, all of the Board’s nominees were reelected by a majority of the votes cast and all of the Company’s proposals have been approved. Mark K. Mason, President and CEO of HomeStreet, said, “On behalf of the entire Board and management team, I would like to thank our shareholders for their support, as well as the highly valuable input they provided during this process. Our focus at HomeStreet continues to be on executing against our clear strategic plan in order to further diversify our business and deliver shareholder value.“In addition, we are committed to translating the feedback we have received from our shareholders into action. We will continue to evaluate our board composition and corporate governance policies to ensure that we are taking the right steps to position the Company for success. We also appreciate the willingness of our shareholders to engage with the Company in discussing our governance practices over the course of the coming year following proxy season. Most importantly, we look forward to further dialogue with our shareholders – as well as our customers, employees and partners – around how best to maximize the potential of HomeStreet moving forward.” The preliminary voting results also indicate that shareholders approved all other proposals considered at the Company’s 2018 Annual Meeting, including the advisory vote (non-binding) to approve executive compensation, proposal on the advisory (non-binding) vote on the frequency of future advisory shareholder votes on executive compensation and the advisory non-binding ratification of the appointment of the Company’s independent registered public accounting firm. The Company will file the voting results, as tabulated by the independent Inspector of Elections, on a Form 8-K with the Securities and Exchange Commission within four business days.

Posted in Estero/world news | Contrassegnato da tag: , , | Leave a Comment »

54th ASCO Annual Meeting in Chicago

Posted by fidest press agency su martedì, 22 maggio 2018

Chicago. ONCODESIGN (Paris:ALONC) (ALONC – FR0011766229), a biopharmaceutical company specializing in precision medicine, announces the publication of an abstract presenting the interim results of the first 12 patients participating in its clinical study with its first radiotracer, for the 54th annual meeting of ASCO (American Society of Clinical Oncology) in Chicago, USA.The primary objective of this clinical study is to assess the clinical interest of the 18F-ODS2004436 radiotracer in PET1 imaging, by determining its sensitivity and specificity in patients with non-small cell lung cancer.In the first stage of the clinical study, 8 patients with EGFR mutations received an injection of the radiotracer. Results showed that the radiotracer did reach and bind to its target, whether a primary or metastatic tumor. The signal reduction after one week’s treatment confirmed the presence of the therapeutic molecule within the tumor. In two of these patients, the radiotracer also alerted the oncologist to the presence of brain metastases, which had gone unnoticed until thenThe results presented at ASCO also include the first four patients recruited in the study’s second stage. These initial results in patients with no EGFR mutation validate the specificity of the radiotracer.
“This 18F-fluorine-labeled radiotracer is a molecule generated using Oncodesign’s Nanocyclix® technology. These interim results reported for ASCO are promising and confirm the preclinical results,” said Philippe Genne, founder, Chairman and CEO of Oncodesign. “The opportunity to present these results at the ASCO annual meeting, the leading event for the international oncology community, is extremely important for Oncodesign and for the visibility of this highly innovative program able to guide clinicians on treatment selection.” Every year, 30,000 oncology experts attend the ASCO meeting to review the latest advances in cancer research. Researchers, physicians and caregivers come to share the results of their clinical and translational work.

Posted in Estero/world news | Contrassegnato da tag: , , | Leave a Comment »