Fidest – Agenzia giornalistica/press agency

Quotidiano di informazione – Anno 31 n° 259

Posts Tagged ‘research’

Japan’s new molecular oncology clinical research

Posted by fidest press agency su giovedì, 20 giugno 2019

QIAGEN (NYSE: QGEN; Frankfurt Prime Standard: QIA) today announced that its QIAGEN Clinical Insight (QCI) offering was selected by the National Cancer Center of Japan, as part of the Japan’s Ministry of Health, Labour and Welfare’s precision medicine program, for the analysis, interpretation and reporting of molecular oncology and oncogenetic screening of cancer patients to contribute to the identification of targeted therapy treatment and clinical trial options.Japan’s Center for Cancer Genomics and Advanced Therapeutics (C-CAT), a unit within the National Cancer Center (NCC) of Japan, will use QIAGEN’s QCI platform including expert curated evidence knowledge bases, bioinformatics software and data center infrastructure to support the C-CAT’s molecular profiling services for core and cooperative hospitals of the country’s cancer genomic medicine program. QIAGEN has established an in-country data center in Tokyo, compliant with Japanese data security and privacy regulations, to support this national program.QCI is a cloud-based clinical decision support software platform used to generate actionable insights from next-generation sequencing (NGS) data. QCI leverages QIAGEN’s expert manually curated evidence knowledge base that includes more than 10 million biomedical findings and thereby be far represents the world’s largest commercial database of curated evidence data on somatic and inherited genetic variants. QCI-Interpret minimizes the complexity and cost of determining the significance of NGS data and automates guidelines for clinical actionability from leading oncology and pathology organizations.

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Research reveals lack of common language in value transformation of U.S. health care

Posted by fidest press agency su mercoledì, 19 giugno 2019

Today’s U.S. health policy initiatives, including those from the Centers for Medicare & Medicaid Services, are aiming to derive more value from the health care dollar. This involves a shift from reimbursement based on volume to reimbursement based on the value of care delivered.With this shift comes a new set of terms being used across the industry, like value-based care and population health. Yet these terms have been found to hold different meanings for different stakeholders, and that has a variety of consequences for health care professionals, health care policymakers, patients, and payers, to name a few.
Humana Inc. (NYSE: HUM), one of the nation’s leading health and well-being companies, and Penn Medicine, set out to find consensus on three terms. Through the use of a Delphi research method that convenes a panel of experts to arrive at a group opinion or decision, lead researcher Marilyn Schapira, MD, MPH, led the panel through multiple rounds of surveys to achieve broadly applicable definitions for three terms: value-based care, value-based payment, and population health.After more than six months, the Delphi panel reached consensus on the term value-based payment but, after three rounds of ratings, was unable to arrive at a consensus definition for value-based care and population health, though distinct areas of agreement and disagreement were made clear. These findings were presented June 3 at the AcademyHealth Annual Research meeting.

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Marine Genetic Resources: Bridging policy, law, science and research and development

Posted by fidest press agency su mercoledì, 29 maggio 2019

Over 65% of the biomass in the ocean is made of plankton. Marine microbes bring services to our ecosystem and their genetic diversity is remarkable. Moreover, marine genetic resources (MGR) have enormous potential in fields such as pharmaceutical, bioremediation, cosmetics, nutraceutical, or biomedical innovation.
MGR in areas beyond national jurisdiction are not regulated. Therefore, the European Commission organised an international workshop on “Marine genetic Resources in areas beyond national jurisdiction: bridging policy, law, science and research and development” on the 21st and 22nd of May in Brussels.Negotiators of the international treaty on marine biodiversity beyond national jurisdiction (BBNJ), top scientists, legal experts and representatives from the private sector and the civil society came together to better understand the scientific process related to the discovery, analysis and use of marine genetic resources (MGR) from areas beyond national jurisdiction, the high seas and the Area. In total, 90 participants from 32 countries. The workshop was an opportunity to bridge the world of the policy makers with the scientific community, legal experts and the private sector, for a better understanding of the scientific process related to the discovery, analysis and use of marine genetic resources (MGR) from areas beyond national jurisdiction, the high seas and its seabed.Participants had the opportunity to discuss important technical aspects related to: the sampling of MGR; their scientific analysis; their storing in collection; the transformation of samples into digital scientific information; examples of applied research; Legal issues , such as intellectual property rights (IPRs) were also high on the agenda.Molecular biologists described how DNA is extracted and transformed into digital data, which then needs to be curated before being analysed.The scientific community stressed the importance of having open access to data, as this is the foundation of scientific investigation. Oceanographers gave an overview of the technologies employed for sampling the deep sea and explained how difficult and costly it is to organise cruises in the high seas. International cooperation is therefore essential and there are plenty of good examples to follow. BBNJ negotiations is a political priority for the European Union. João AGUIAR MACHADO, Director General of DG MARE, stressed the importance in engaging with the scientific community and the private sector, with the support of the civil society organizations, in the ongoing negotiations.
The President of the BBNJ intergovernmental conference (IGC) at the UN, Rena Lee, underlined the need to base the negotiations on solid scientific knowledge and to look for practical solutions, through a pragmatic approach.

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The new website of IDOS Research and Study Centre

Posted by fidest press agency su giovedì, 9 maggio 2019

From today the new website of IDOS Research and Study Centre, entirely renewed in its layout, contents and functions, is online. The website has been implemented thanks to the technical support of Lai Momo cooperative association, which for many years has been collaborating with IDOS to realize and promote the annual socio-statistical report on immigration in Italy, Dossier Statistico Immigrazione – Statistical Dossier
on Immigration, together with other publications and events. On the new website (www.dossierimmigrazione.it) everyone can find not only detailed information on all
events promoted by IDOS or where IDOS is called to intervene (meetings, conferences, seminars, courses, interviews and other training and/or sensitization activities), but also news and updates useful for operators and researchers, original reports edited by IDOS network of local researchers, press releases, socio-statistical tables and summaries, videos, graphics (all things that can be downloaded or pressed) concerning studies and publications annually edited by IDOS. What’s absolute new is that for the first time everyone can buy online all IDOS publications, both in paper format and – at a lower price – in digital format (pdf), through a fast, easy and sure online system of payment and invoice. In particolar, for every main annual report (Dossier Statistico Immigrazione – Statistical Dossier on Immigration, Osservatorio Romano sulle Migrazioni – Roman Observatory on Migrations, Rapporto Immigrazione e Imprenditoria – Report on Immigration and Entrepreneurship, etc.), it’s available for sale both the entire book and – separately purchasable in electronic format only – every single thematic chapter and the final addendum of statistical tables. Many other monographic publications, periodically edited by IDOS in collaboration with – or for commission of – some private or institutional bodies, are also available in addiction to such a rich archive of annual reports.

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Research and innovation for the global community

Posted by fidest press agency su mercoledì, 8 maggio 2019

For 70 years now, the researchers at the Fraunhofer-Gesellschaft in Germany have been asking the right questions and finding answers – in the form of solutions that improve society and directly benefit the economy. This year marks an anniversary in the U.S., too: the establishment of Fraunhofer USA as a legally independent Fraunhofer affiliate 25 years ago. This non-profit organization was founded in 1994 to conduct applied research and development for customers from industry and from the federal and state governments in the U.S. With a history of more than 15 years now, the collaboration with Michigan State University (MSU) is a prime example of the continued success of this transatlantic research alliance.
25 years of Fraunhofer USA – 15 years of cooperation with Michigan State University (f.l.t.r.): Prof. Thomas Schuelke, President Fraunhofer USA, Prof. Leo Kempel, Dean of MSU College of Engineering, Prof. Reimund Neugebauer, President of the Fraunhofer-Gesellschaft, Satish Udpa, President of the MSU, Prof. Endrik Wilhelm, Chairman Fraunhofer USA, Prof. John Papapolymerou, MSU-Chair Electrical and Computer Engineering, Pär Malmhagen member of the Senate of the Fraunhofer-Gesellschaft.
The success of the close collaboration between MSU and the Fraunhofer USA Center for Coatings and Diamond Technologies USA CCD is typical of the transatlantic research alliance. This collaboration between the Fraunhofer-Gesellschaft, Fraunhofer USA, MSU and the Fraunhofer Institute for Material and Beam Technology IWS in Dresden dates back more than 15 years and has resulted, for instance, in the development of process and system technologies for manufacturing high-quality diamond materials for applications in power and high-frequency electronics.
Fraunhofer USA CCD conducts research projects focusing particularly on coating technologies, carbon materials and 3D printing technologies, with a total project volume of USD 2.8 million per year. With industrial revenues accounting for 43 per cent of this figure, Fraunhofer USA CCD is thus also a prime example of the success of the Fraunhofer model abroad.
During his visit to the United States to mark the 25-year anniversary of Fraunhofer USA, Prof. Neugebauer was awarded an honorary doctorate from MSU in acknowledgment of his contributions to application-oriented research and to the transatlantic research alliance. Prof. Neugebauer thus joins the ranks of many others who have been awarded this honorary MSU degree for their outstanding work in research or the management of public organizations, including automotive pioneer Henry Ford, Apple co-founder Stephen Wozniak, and former U.S. presidents Harry Truman and Bill Clinton.

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CWT Research: Two-Thirds of Travelers Pick Window Over Aisle; 52% Prefer Missed Flight Over Lost Luggage

Posted by fidest press agency su mercoledì, 1 maggio 2019

Minneapolis. Research by CWT, the B2B4E travel management platform, shows that two-thirds of business travelers prefer window seats over aisle seats. That rises to 71% in Asia Pacific, and falls to 59% in the Americas, with the Europeans in the middle at 65% window over aisle.Globally, a narrow majority of business travelers would prefer to miss their flight rather than be separated from their luggage – with travelers from the Americas showing the strongest preference at 54%, European travelers at 52%, and travelers from Asia Pacific split down the middle.When it comes to ground transportation, 54% of travelers still prefer traditional taxis over ridesharing services like Lyft or Uber. But there are strong regional differences. In Europe, a full 69% Europeans prefer taxis – almost exactly the reverse of American travelers, 63% of whom prefer rideshare services. Asia Pacific travelers are more evenly split, with 56% preferring taxis.
“These findings provide fascinating and sometimes counter-intuitive insights into how global business travelers approach their journeys,” said Niklas Andreen, Executive VP and Chief Traveler Experience Officer at CWT. “We see significant differences between regions – for example, in Asia, people are more likely to want a window seat, whereas in markets like the US, the view is less of a draw.”CWT’s research also shows that travelers are generally happy to share their travel preferences with both apps and travel industry staff – globally nine out of ten (89%) of travelers are “extremely or “somewhat” willing to do so. That applies equally to business travel and leisure travel, suggesting that travelers make little distinction between the two, at least when it comes to sharing information on their personal preferences.The data show that, overall, European travelers are least willing to share data: 14% of Europeans are “not willing” to share their preferences either with apps or people while traveling for business. That rises to 17% when traveling for leisure. Travelers from the Americas or Asia Pacific are much less likely to refuse to share their preferences, especially when traveling for leisure.

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New Absolute Research Reveals That Endpoint Security Tools Fail, Reliably and Predictably

Posted by fidest press agency su venerdì, 19 aprile 2019

Absolute (TSX: ABT), the leader in endpoint resilience, today revealed that endpoint security tools and agents fail, reliably and predictably, based on findings from its new 2019 Global Endpoint Security Trends Report. From there, every additional security tool only amplifies complexity and increases the probability of failure and decay, in turn, exposing the dangers of equating IT security spending with security and risk maturity. The study analyzed data from six million devices and one billion change events over the course of a year.The endpoint has quickly become valuable real estate for security tools and controls, as traditional network perimeters have given way to cloud-based models in support of the digital workforce. Global security spending is forecast to reach $128 billion by 2020 with endpoint security spend comprising 24 percent of that total(1), and yet, over 70 percent of breaches originate on the endpoint. The complexity of endpoint device controls creates a false sense of security among organizations while, in reality, causing security gaps and significant risks due to regular and reliable tool failure. Staggering findings on endpoint security degradation include:
42 percent of all endpoints are unprotected at any given time. Two percent of endpoint agents fail per week, meaning 100 percent of endpoint security tools eventually fail – no tool is immune28 percent of all endpoints are unprotected by anti-malware with 21 percent of these endpoints unprotected due to outdated or broken agents and 7 percent due to missing agents 100 percent of devices will have failed encryption controls at least once within one year. Almost 1 in 5 devices become unreachable due to client management tool failures Client patch management agents fail around 50 percent more often than encryption agents As cybercrime threatens to cost the world $6 billion annually in damages by 2021, organizations need to address these issues. IT and security teams must be able to better understand what is happening on their devices and respond to suspicious events to reduce security failures. Organizations should analyze the tools already in use to identify blind spots or opportunities to strengthen their defenses before adding more security controls.
The “2019 Endpoint Security Trends” report analyzes data compiled over the course of a year by Absolute’s security research team. The devices represent data from 12,000 anonymized organizations across North America and Europe, and a third-party research organization was commissioned to conduct in-depth, exploratory interviews with senior executives from Fortune 500 companies to offer context to the findings.

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Company Profile for ABI Research

Posted by fidest press agency su sabato, 23 marzo 2019

ABI Research provides strategic guidance for visionaries needing market foresight on the most compelling transformative technologies, which reshape workforces, identify holes in a market, create new business models and drive new revenue streams. ABI’s own research visionaries take stances early on those technologies, publishing groundbreaking studies often years ahead of other technology advisory firms. ABI analysts deliver their conclusions and recommendations in easily and quickly absorbed formats to ensure proper context. Our analysts strategically guide visionaries to take action now and inspire their business to realize a bigger picture. For more information about subscribing to ABI’s Research Services as well as Industrial and Custom Solutions, visionaries can contact us at +1.516.624.2500 in the Americas, +44.203.326.0140 in Europe, +65.6592.0290 in Asia-Pacific or visit http://www.abiresearch.com.

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“Research Report on Paper and Paperboard Import in China, 2019-2023”

Posted by fidest press agency su lunedì, 18 marzo 2019

Based on this research, the demand for paper and paperboard imports in China will continue to grow from 2019 to 2023.The major driving forces include the lower average price of imports than domestic counterparts and the sluggish growth in domestic production of paper and paperboard resulting from the shortage of raw materials and the upward costs of labor, land, energy resources and other production factors.
According to this analysis, with the development of China’s economy and the improvement of living standards, the per capita consumption of paper and paperboard shows an upward trend. Meanwhile, China’s net annual population growth is between 8 million and 10 million, which leads to an increasing demand for paper and paperboard in China and promotes the development of China’s papermaking industry.However, the papermaking industry is dependent on forest resources which are scarce in China. As China tightens its environmental protection policies and the forest coverage rate decreases, the fiber materials for papermaking are in increasingly short supply. Besides, the labor costs in the Chinese manufacturing sector keeps rising. Therefore, China needs to import a large quantity of paper and paperboard to cover the shortage of domestic capacity.
The Chinese government has set no administrative barriers against paper and paperboard import, e.g. making paper and paperboard exclusive to state-owned enterprises, or introducing import quota administration for paper and paperboard. But import tariffs vary greatly among China’s paper and paperboard imports. For instance, the MFN rate and general rate on the commodity that has the heaviest tax burden is respectively 35% and 100%. The import tariffs on newsprint, kraft paper, etc. are lower with the lowest MFN rate being 2%.
According to this analysis, the import volume of paper and paperboard in China is rising in recent years. It reached 6.27 million tons in 2018, increasing by 122.3% as compared to 2014. And the import value reached USD 5.53 billion, increasing by 54% as compared to 2014.
The reasons for the growing paper and paperboard imports mainly include: (1) The price of imported paper and paperboard is lower than that of domestic counterparts; and (2) the quality of imported paper and paperboard is better than that of domestic counterparts. But market trends vary greatly among China’s paper and paperboard imports.Overall, product segments that have great price differences with domestic counterpart see faster growth. For example, with the development of Intermedia, the sales volume of newspaper, magazines and other print media is decreasing in China, which brings down the demand for newsprint. However, the import volume of newsprint in China grew by 860% from 2014 to 2018 because the price of imported newsprint was far lower than that of domestic newsprint.In recent years, the demand for liner board keeps rising with the rapid development of the e-commerce and logistics industries. As the import price differed little from the domestic market price, the import volume of liner board in China grew by only 65.10% from 2013 to 2017.

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Cutting-Edge Option Care Research Presented at NHIA Finds Home IV Antibiotic Method Can Affect Adherence, Cost

Posted by fidest press agency su sabato, 16 marzo 2019

New research by Option Care Enterprises, Inc. (“Option Care”), the nation’s leading provider of home and alternate site infusion therapy services, suggests the method of antibiotic intravenous (IV) administration can improve patient compliance while decreasing costs. The study1 was presented today at the National Home Infusion Association (NHIA) Annual Conference and is a finalist for the “Outstanding Abstract Achievement Award.”
The researchers analyzed patient compliance by comparing four techniques for antibiotic self-administration and determined ease of providing therapy was a significant factor. They concluded patients were significantly more likely to comply with therapy if they used the elastomeric pump or IV push than if they used the gravity/mini bag or electronic pump. Additionally, in many cases IV push and elastomeric pump are less costly.“There’s a common perception that the gravity/mini bag is the least expensive method, but our research shows not only are IV push and elastomeric pump often more cost-effective, but patients find them easier to use, decreasing the likelihood that they will skip doses, which can lead to failed therapy and hospital readmission,” said Julie Wurdeman, PharmD, an Option Care infusion pharmacist and primary author of the study. “Our findings have implications for helping establish the most appropriate method of administration and underscore the value of collaboration among patients and the care team.”
The type of IV antibiotic therapy typically is chosen by the pharmacist in collaboration with the physician and determined by several factors including the medication, frequency of therapy (typically one to three times a day), rate of infusion as well as provider preference, patient lifestyle and age. The research suggests that patient compliance and cost should be factored into the equation.Researchers studied treatment compliance in 688 Option Care home infusion patients who were treated between October 2017 and October 2018 and who missed one or more doses of IV antibiotics. They found the percentage of doses missed by technique was: 2.6 percent elastomeric pump, 2.7 percent IV push, 5 percent mini bag and 8.6 percent electronic pump.There is a wide variation between methods in the cost of administration (factoring in equipment, compounding and patient education, but not medication), including a 209 percent difference between the least-expensive, IV push, and the most-expensive, electronic pump. The cost varies depending on the number of times per day and the rate at which the antibiotic is provided, as well as whether equipment can be reused and other factors.In home antibiotic therapy, the patient infuses the medication through a catheter (placed by a nurse in a vein, usually in the hand or arm).

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KBRA Releases Research on Auto Loan Extensions

Posted by fidest press agency su mercoledì, 27 febbraio 2019

Kroll Bond Rating Agency (KBRA) releases a research report examining the use of subprime auto loan extensions as a loss mitigation tool for ABS servicers. In general, KBRA believes the use of extensions ultimately benefits ABS investors by reducing delinquency and default rates. However, a high rate of extensions within a securitized collateral pool can meaningfully increase bond duration and expose ABS investors—particularly owners of deeply subordinated tranches—to tail risks. As such, it is important for investors to understand each servicer’s policy regarding extensions, as well as how extensions are handled within ABS deal structures.
KBRA is a full service credit rating agency registered with the U.S. Securities and Exchange Commission as an NRSRO. In addition, KBRA is designated as a designated rating organization by the Ontario Securities Commission for issuers of asset-backed securities to file a short form prospectus or shelf prospectus, is recognized by the National Association of Insurance Commissioners as a Credit Rating Provider, and is a certified Credit Rating Agency (CRA) by the European Securities and Markets Authority (ESMA). Kroll Bond Rating Agency Europe Limited is registered with ESMA as a CRA.

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Research in Otolaryngology (ARO) Conference

Posted by fidest press agency su venerdì, 8 febbraio 2019

Decibel Therapeutics will showcase capabilities across its inner ear-focused drug discovery and development platform at the 42nd annual mid-winter meeting of the Association for Research in Otolaryngology (ARO) from February 9-13, 2019. The data to be presented will demonstrate new insights on the delivery of medicines to the inner ear through multiple modalities, including gene therapy and biologics, as well as the development of biomarkers, assays and tools to address cochlear synaptopathy and other disorders.“This last year has been transformative for Decibel,” said Michael Su, Ph.D., Decibel’s chief scientific officer. “Not only have we advanced two compounds for the prevention of hearing loss into Phase I clinical studies, but we’ve also strengthened our discovery and delivery capabilities in support of our early stage pipeline programs in monogenic hearing loss, tinnitus and balance. We’re looking forward to sharing this broader suite of capabilities with our colleagues at ARO.”

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“Research Report on Timber Import in China, 2019-2023”

Posted by fidest press agency su giovedì, 24 gennaio 2019

According to the report, in 2017, Russia, the U.S., New Zealand and Canada, the four largest sources of China’s timber imports, provided 64% of the total import volume of timber in China. In particular, Russia and the U.S. provided about 31% and nearly 10% respectively of the total timber imports.On August 3, 2018, China’s Ministry of Commerce announced a 5% to 25% tariff increase on U.S. exports worth USD 60 billion, including a 25% tariff increase on U.S. timber. Evidently, the Sino-U.S. trade war will have a certain impact on China’s timber import.
The domestic supply of merchantable timber has been contracting, and China’s reliance on timber imports has exceeded 50% since the Chinese government announced the prohibition on the commercial cutting of natural forests in 2017. It is expected that the international timber prices will show an upward trend in the next few years as the import volume of timber keeps rising in China.Some Chinese enterprises have begun to invest in the forestry industry in other countries, mainly Russia, to ensure a stable and adequate supply of timber. By the end of 2018, more than 100 Chinese enterprises had invested in Russia’s forestry industry with a total of over USD 2 billion – and the figures are expected to grow further.The Chinese government has few restrictions on timber import. Therefore, the Chinese market will provide global forestry enterprises with numerous opportunities in the next few years.

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Elligo Health Research Acquires Protenium Clinical Research

Posted by fidest press agency su venerdì, 11 gennaio 2019

Elligo Health Research, an integrated research organization, has acquired Protenium Clinical Research. Protenium, an established research group led by Robert Strzinek, Ph.D., D.O., conducts pharmaceutical studies in a broad range of therapeutic areas.Dr. Strzinek has more than 15 years of clinical research experience and will now conduct research at his practice in partnership with Elligo. The acquisition brings the number of patients in Elligo’s Research Ready network to more than one million. As part of Elligo’s Goes Direct® approach, these patients will now have access to clinical research as a care option from their own trusted physician.“Joining Elligo’s Dallas–Fort Worth Community of Research will ensure that we continue to provide the best clinical research opportunities to our patients and help us expand research opportunities across the region,” said Dr. Strzinek. “Our partnership allows us to focus on patient care while benefiting from Elligo’s research relationships and operational expertise.”Dr. Strzinek has completed over 150 research studies and authored numerous journal articles covering several areas including endocrinology and women’s health. He and the Elligo team will continue to conduct research and support other community-based health care providers participating in research.“The opportunity to leverage Dr. Strzinek’s highly experienced practice and integrated clinical operation in our Research Ready network and Communities of Research furthers our mission to bring together and empower health organizations and improve clinical trial access and efficiency,” said John Potthoff, Ph.D., CEO at Elligo. “We are delighted to welcome him, and his staff and patients to the Elligo family.”

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The “Mining Investment Asia” conference has been added to ResearchAndMarkets.com’s offering

Posted by fidest press agency su giovedì, 10 gennaio 2019

Singapore – March 27-28, 2019. Mining Investment Asia is a strategic mining conference and exhibition for the leaders of the mining, quarrying and construction materials industries, bringing together 350 attendees from 24 countries.Ministers, mining companies, investors and service providers travel from all over Asia, North America, Europe, Middle East and Africa for four days of partnering, networking and business matching.Join us at an invaluable platform to seek new partnerships, new business and new opportunities.
The event delivers the highest level audience in the region, allowing you to speak and network with key buyers and industry leaders under one roof.The speakers are industry leaders and provide new perspectives on key issues disrupting & innovating mining sector, share cutting edge content and insights on the mining landscape.For more information about this conference visit  https://www.researchandmarkets.com/research/zkcbwj/2day_conference?w=4

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New research reveals 4.8% of the UK population have elevated liver iron

Posted by fidest press agency su lunedì, 24 dicembre 2018

The study, conducted by the University of Westminster and Perspectum Diagnostics, used MRI to non-invasively assess levels of liver iron. The numbers of individuals with abnormal levels for two key risk factors of significant liver disease are considerable and represent potentially 2 million NHS patients. The UK health system is under-prepared for the current liver disease epidemic.Iron overload is traditionally associated with genetic disorders such as hereditary haemochromatosis (HH) or as a results of repeated blood transfusions. However elevated levels of liver iron are now often associated with metabolic diseases including insulin resistance, type 2 diabetes and NAFLD. Elevated liver iron is associated with the development of fibrosis and cirrhosis and thought to be involved in the progression from fibrosis to liver cancer.Diagnostic pathways for liver iron currently rely on simple blood tests, which often miss early stages of iron accumulation, and liver biopsy. However, ferritin levels can be influenced by liver damage and inflammation, and in many cases do not correlate well with liver iron stores. Therefore, the development of robust, widely available and non-invasive techniques for the measurement of liver iron are needed. This study used the quantitative MRI behind LiverMultiScan to safely and painlessly assess liver health.Haemochromatosis UK, the national charity representing patients with iron overload, have recently launched an awareness campaign in the House of Commons, and received support from the UK government, the National Consortium of Intelligent Medical Imaging, and GE Healthcare and Perspectum Diagnostics, to improve the availability of MRI scanners with LiverMultiScan and automated image processing to identify NHS patients with iron overload.

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A new report from Navigant Research

Posted by fidest press agency su venerdì, 21 dicembre 2018

It examines the cybersecurity landscape for intelligent buildings and the implications of increased Internet of Things (IoT) connectivity. While smart buildings are centered around the ideas of connectivity and interactivity, new interfaces are dramatically increasing access points, providing gateways to sensitive data, and creating new vulnerabilities for building automation systems. Further, the proliferation of IoT-enabled devices and third-party entities has widened the surface area for attack, compounding the security issue by making threat detection less straightforward and more difficult to remedy. Click to tweet: According to a new report from @NavigantRSRCH, this nascent IoT cybersecurity market is expected to show steady growth as the demand for strong security solutions continues to increase.“Cybersecurity issues are expected to grow in tandem with the digital transformation of real estate through intelligent building technologies,” says Casey Talon, research director with Navigant Research. “The information/operational technology (IT/OT) convergence is a necessity for successful deployment and the use of intelligent building solutions, but in many customer organizations, these business units act in isolation. This creates gaps in human capital skill sets, resulting in infrastructure and processes that can be vulnerable to cybersecurity breaches.”Navigant Research recommends intelligent building stakeholders take a proactive approach to cybersecurity threats by determining vulnerabilities and attack vectors and educating the enterprise. Stakeholders should take a layered approach to cybersecurity, in addition to building a cyber threat alliance and continuing to strengthen their line of defense. The report, Cybersecurity Will Define Market Leaders in the Intelligent Buildings Market, examines the cybersecurity landscape for intelligent buildings and the implications of increased IoT connectivity. It analyzes several best practices and strategies that managers and vendors are taking to secure intelligent building systems. The report also provides a list of recommendations for stakeholders to integrate into their cybersecurity frameworks as they continue to build resilience against threat vectors. An Executive Summary of the report is available for free download on the Navigant Research website.

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Research Collaboration to Investigate Markers of Immuno-Oncology Response and Resistance

Posted by fidest press agency su giovedì, 20 dicembre 2018

Bristol-Myers Squibb Company (NYSE:BMY), and Boston Medical Center, a private, not-for-profit, academic medical center, today announced a multi-year joint research study to identify and analyze potential sensitivity and resistance markers in patients treated with standard-of-care checkpoint inhibitors. The comprehensive, multi-dimensional study will place an emphasis on uncovering mechanisms associated with lack of response to Immuno-Oncology (I-O) therapies, with the ultimate goal of identifying prognostic and potentially predictive I-O biomarkers in a variety of cancers.“Our newly opened R&D site in Kendall Square is focused on better understanding, and ultimately overcoming, the challenge of I-O resistance. We are thrilled to establish our first partnership since the site opened with our new neighbor, Boston Medical Center, with the goal of uncovering new insights into the biology of cancer and how it evolves with exposure to I-O intervention,” said Saurabh Saha, M.D., Ph.D., senior vice president and global head of translational medicine, Bristol-Myers Squibb. “The information we glean from this collaboration will ultimately inform the development of novel therapeutic strategies to improve response rates and outcomes for patients.” Through the study, researchers will explore the role of tissue and circulating biomarkers on treatment sensitivity and resistance. In addition, scientists will investigate the role of the microbiome as a potential predictive biomarker in patients receiving treatment with immune checkpoint inhibitors.“Boston Medical Center serves a diverse patient population, with 70 percent of our patients coming from underserved communities,” said Matthew Kulke, M.D., chief of hematology/oncology at Boston Medical Center. “These patients are sorely underrepresented in current research studies. We look forward to partnering with Bristol-Myers Squibb on this study to identify and assess biomarkers across a diverse patient population, providing us with a deeper and more comprehensive understanding of I-O resistance.” The two organizations will jointly conduct the research throughout the duration of the study, after which Bristol-Myers Squibb and Boston Medical Center may collaborate to publish results.

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Convegno “EU Research and Innovation in our daily life”

Posted by fidest press agency su domenica, 2 dicembre 2018

In Europa si registra il 25% del totale dei casi del cancro diagnosticati nel mondo, una percentuale molto elevata se si considera che nel Vecchio continente vive solo il 9% della popolazione mondiale. Ogni anno circa 4 milioni di cittadini europei sono colpiti da tumore. La mortalità per cancro è diminuita nei Paesi occidentali negli ultimi 25 anni (per quasi tutte le forme neoplastiche), soprattutto nelle donne rispetto agli uomini per la diffusione dei programmi di screening e trattamenti più efficaci. La sopravvivenza netta a 5 e 10 anni è costantemente aumentata negli ultimi anni fino all’80-90% nei tumori della tiroide, della prostata, della mammella e nel melanoma, ma è ancora bassa (circa il 10-20%) nei tumori del cervello, del fegato, del polmone, dell’esofago e del pancreas. È questo il quadro descritto oggi dal prof. Francesco Cognetti, Presidente di Fondazione Insieme Contro il Cancro nella relazione sulle “Nuove frontiere nella lotta contro il cancro” al convegno EU Research and Innovation in our daily life presso il Parlamento Europeo a Bruxelles. “I miglioramenti sono costanti nel tempo – spiega il prof. Cognetti -, ma permangono variazioni tra Paesi europei con differenze nelle cure oncologiche legate a diverse ragioni: l’intensità diagnostica e lo screening che portano a una diagnosi più precoce o tardiva, i trattamenti efficaci, lo stato socioeconomico, lo stile di vita e differenze di salute generale nella popolazione, i costi per i tumori e l’organizzazione delle cure. I dati di sopravvivenza sono migliori in Europa del Nord e centrale e in alcuni Paesi del Sud (Italia e Spagna). Sono invece peggiori nel Regno Unito e in Europa orientale”.
“Per aiutare a ridurre le differenze di sopravvivenza e migliorare le cure oncologiche – osserva il prof. Cognetti -, tutti i Paesi europei dovrebbero perseguire la riduzione della frammentazione dei servizi di cura, promuovere centri multidisciplinari comprensivi di cure oncologiche, una migliore organizzazione e finanziamento del sistema sanitario, la promozione e il finanziamento della ricerca e l’alleanza dell’intera comunità contro il cancro. L’intensa collaborazione tra comunità scientifica, medica, tecnologica e farmaceutica è quindi indispensabile”.

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EU Research and Innovation in our daily life

Posted by fidest press agency su sabato, 24 novembre 2018

Bruxelles i terrà il 27 novembre 2018 a Bruxelles, presso la sede del Parlamento Europeo, la Conferenza congiunta di Parlamento europeo e Commissione europea EU Research and Innovation in our daily life, che riunirà ricercatori, politici, rappresentanti delle istituzioni e dell’industria e vedrà la presenza di personalità come Antonio Tajani, Presidente del Parlamento europeo, Carlos Moedas, Commissario europeo per la Ricerca, la Scienza e l’Innovazione e Jean-Pierre Bourguignon, Presidente del Consiglio europeo della Ricerca.
L’incontro intende stimolare gli investimenti nella ricerca, dando uno sguardo ad alcuni tra i maggiori traguardi che l’Unione Europea ha raggiunto in tema di ricerca e innovazione e che sono il risultato di un continuo dialogo tra le istituzioni europee, gli stati membri, le loro università e i centri di ricerca più importanti.A rappresentare la ricerca italiana di eccellenza il professor Luigi Naldini e il professor Alessandro Aiuti, direttore e vice direttore dell’Istituto San Raffaele-Telethon per la Terapia Genica (SR-Tiget), che presenteranno, attraverso il racconto dei genitori, la storia di Margaux, una bambina belga affetta da ADA-SCID, rara malattia genetica che compromette gravemente il sistema immunitario, e curata con successo grazie alla terapia genica sviluppata presso il SR-Tiget di Milano.Margaux oggi ha 5 anni ed è una dei 31 piccoli pazienti affetti da ADA-SCID trattati ad oggi con la terapia genica sviluppata dall’Istituto San Raffaele-Telethon, dal 2016 è divenuta un farmaco e la prima terapia genica con cellule staminali ematopoietiche a essere disponibile sul mercato.

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