Fidest – Agenzia giornalistica/press agency

Quotidiano di informazione – Anno 32 n° 250

Posts Tagged ‘selection’

Selection of a small molecule tau oligomer inhibitor for IND enabling studies

Posted by fidest press agency su venerdì, 18 ottobre 2019

Chicago October 22, 2019 Time: 10:00 am – 10:15 am McCormick Place, Room S103 Oligomerix, Inc., a privately held company pioneering the development of tau oligomer inhibitors for Alzheimer’s disease (AD) and related neurodegenerative disorders, will present preclinical data on its lead product candidate at Neuroscience 2019, the 49th annual conference of the Society for Neuroscience, being held in Chicago from October 19-23. In an oral presentation, James Moe, Ph.D., MBA, President and CEO of Oligomerix® will discuss the results of in vitro and in vivo studies with its small molecule tau inhibitor. There is a critical unmet need for disease-modifying drugs for AD and related dementias, and the role tau plays in the disease has become an important target for drug discovery and development. Oligomerix and other research labs have shown that tau oligomers are directly neurotoxic, inhibit signal transmission between neurons, and impair formation of memory in mice. Oligomerix’s core technology is focused on developing small molecule inhibitors of tau self-association, the initial step in the formation of pathological tau oligomers at the beginning of the tau aggregation cascade. Oligomerix’s lead compound has demonstrated efficacy in preclinical studies, and preclinical safety studies are in progress. A complementary mechanistic biomarker is being developed to facilitate clinical development.

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Martha Hughes Cannon Statue Oversight Committee Narrows Down Selection to Five Sculptors

Posted by fidest press agency su venerdì, 14 dicembre 2018

The Martha Hughes Cannon Statue Oversight Committee announced today that it has narrowed down its selection to five sculptors as part of the Request for Qualifications/Proposal process publicly announced on September 18 with a deadline to submit by November 4. The five finalists include Jane DeDecker from Colorado, Edward J. Fraughton from Utah, Ben Hammond from Utah, Dora Natella from Indiana and Dennis Smith from Utah.Finalist interviews by the Martha Hughes Cannon Oversight Committee will take place between February 4 and 6. The final artist selected to create the Martha Hughes Cannon sculpture will be announced on February 14, 2019, the same day Utah will be celebrating the anniversary of the first vote cast.“The Martha Hughes Cannon Statue Selection Committee was so pleased by the interest in this commission,” said Jen Christensen, the chair of the Martha Hughes Cannon Oversight Committee. “The five selected finalists represent a diverse group of exceptionally qualified artists. We are looking forward to meeting each sculptor and seeing their maquette concepts for this remarkable woman in early February.”Utah women were the first to vote in the modern nation on February 14, 1870 and the Martha Hughes Cannon statue will arrive in Washington, D.C. in 2020 as a symbol of Utah’s role in the national suffrage movement and to commemorate the 100th anniversary of the 19th Amendment. For more information, visit http://www.sendmartha.com.A leader in the Utah Women’s Suffrage Association, Dr. Martha Hughes Cannon testified before U.S. congressional committees and was a featured speaker at national suffrage conventions. “As the first female state senator in the United States, Martha Hughes Cannon deserves to be recognized for providing the foundation for many subsequent impactful women in American politics,” said Utah State Senator Deidre Henderson. “We all stand on the shoulders of women like Martha Hughes Cannon and look forward to having her statue placed in National Statuary Hall for onlookers to revere.”

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A selection of international names

Posted by fidest press agency su lunedì, 13 giugno 2016

christie's london(by Belinda Bowring) Christie’s will bring together a selection of international names in the Post-War and Contemporary Art Auctions on 29 and 30 June at London’s King Street. This season’s auctions are complemented by a strong core of Post-War and Contemporary art in Christie’s 250th anniversary sale Defining British Art, including Francis Bacon’s landmark canvas Version No. 2 of Lying Figure with Hypodermic Syringe (1968) and Lucian Freud’s Ib and her husband, (1992).Early works by Pop icons Andy Warhol and Roy Lichtenstein lead the evening auction and are joined by a central group of the next-generation of American artists including Felix Gonzalez-Torres, Mike Kelley, Glenn Ligon, and Kelley Walker. A major highlight of the sale will be a capsule selection of works by Jean-Michel Basquiat from the collection of celebrated actor Johnny Depp. Giants of European painting feature firmly with Gerhard Richter’s Abstraktes Bild (811-2) leading the line-up. This season the field of Post-War and Contemporary Art, across all auctions, is estimated to total over £90,000,000. Featuring 45 lots, the Post-War and Contemporary Evening Auction will be a centrepiece of 20th Century at Christie’s, a series of auctions that take place from 17 to 30 June. Francis Outred Chairman and Head of Post War and Contemporary Art, EMERI: “This June promises to be the most exciting presentation of Post-War and Contemporary Art at Christie’s in many years. Combining the celebration of our 250 years, led by works in the Defining British Art Loan Exhibition and Evening Auction that include masterpieces by Bacon, Freud, Riley and Auerbach, together with defining works from the oeuvres of Warhol, Lichtenstein, Richter and Basquiat.”  (photo: christie’s london)

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500 años del Orlando Furioso

Posted by fidest press agency su venerdì, 2 ottobre 2015

orlandoMadrid se inaugura el 6 de octubre, una selección (1516-2016. 500 años de Orlando Furioso) estará abierta hasta el 17 de enero del próximo año, y se realiza en colaboración con el Istituto Italiano di Cultura de Madrid y el Teatro Real.7 de septiembre del 2015 – Anticipándose al estreno de la Alcina de Haendel en el Teatro Real, la Biblioteca Nacional de España contextualiza la ópera mediante una exposición de sus fondos sobre el Orlando furioso, el inmortal poema de Ludovico Ariosto (1474-1533), que le sirve de inspiración y que cumple en el 2016 cinco siglos de su primera redacción. La muestra, bajo el título El Furioso en la BNE.
Podrán verse ediciones del texto de Ariosto junto con sus más cercanos antecedentes y continuadores, así como una selección de piezas que pretenden devolver a este clásico, muy olvidado hoy en nuestro país, parte de la notoriedad de la que gozó universalmente, sobre todo, en Italia y España, en siglos anteriores. Para ello, se han seleccionado cerca de cuarenta ejemplares, como un manuscrito de la compañía teatral de Bances Candamo, dibujos y grabados, entre los que destacan Angélica y Medoro, de Charles de la Traverse o los bocetos de Sebastián Muñoz para una bóveda del alcázar de Madrid, así como libros de los siglos XVI y XVII, que dan idea, no solo de los poemas que lo precedieron, sino también de las numerosas ediciones, traducciones, imitaciones y continuaciones que de él se hicieron casi desde el mismo momento de su aparición.Es un poema de aventuras, amoríos, celos, traición, despecho, olvido, orgullo…, donde la fantasía más desbocada encuentra el equilibrio en una fina y jocosa ironía. Aquella fue la fórmula de éxito del primer bestseller de la Edad Moderna, creación de todo un “fanfic” de Orlando como Ludovico Ariosto, que halló en la obra de su vida la perfecta válvula de escape a su nula sed de aventuras y espíritu viajero.Completa la exposición la conferencia del profesor José María Micó, el día 6 de octubre a las 19:00, Ariosto, el Orlando y su herencia cultural. Micó es catedrático de literatura en la Universidad Pompeu Fabra de Barcelona. Escritor y filólogo, consiguió premios literarios como Hiperión y Generación del 27, de traducción y de investigación. Ha estudiado y editado a los clásicos españoles e italianos y es autor de la última traducción castellana del Orlando (Espasa-Calpe, 2005). Por su parte, el Instituto Italiano organiza una representación del monólogo Orlando furiosamente solo rotolando, para el día 8 de octubre, a las 20h00 con entrada libre hasta completar el aforo. http://www.iicmadrid.esteri.it/iic_madrid/it/gli_eventi/calendario/2015/10/orlando-furiosamente-rotolando.html
Además, se organizarán talleres infantiles y escolares y otras actividades sobre esta obra, con la colaboración de la editorial Gadir, que ha publicado una adaptación infantil del Orlando enamorado junto con el Furioso.
Descendiente del Orlando innamorato de Boiardo, y, a su vez, del Morgante de Pulci, el Furioso vincula su complicada y fantasiosa trama al ciclo artúrico y al carolingio, con una ironía que preludia la del Quijote cervantino. La obra de Ariosto no sirvió solo de inspiración literaria, desde Lope de Vega a Barahona de Soto, sino también resuena en composiciones musicales de Händel o Vivaldi, como la propia Alcina, o ha sido plasmado con las más diversas técnicas de artes plásticas y aplicadas por una nómina de artistas, que incluye nombres como los de Tiziano, Guido Reni, Ingres o Doré.El poema y epopeya se compone de cuarenta y seis cantos escritos en octavas (38.736 versos) por los que deambulan personajes del ciclo carolingio, algunos del ciclo bretón (gruta de Merlín, visita de Reinaldo de inauguraciònMontalbán a Inglaterra) e incluso algunos seres inspirados en la literatura clásica griega y latina. Es, y así la presenta el autor, una continuación del Orlando enamorado de Matteo Maria Boiardo. Allá donde dejó éste inacabada su obra, la derrota del ejército de Carlomagno en los Pirineos por los árabes, es donde arranca el Ariosto la suya, que suele, al reintroducir los personajes de su predecesor, dedicar una o dos octavas a resumir las aventuras narradas por Boiardo en el Enamorado.A pesar de su título, Orlando (o Roldán, si se prefiere) no es el protagonista absoluto del poema, sino uno de los personajes principales que aparecen en él. La obra es un continuo entrelazarse de historias de distintos personajes que van apareciendo y desapareciendo en la narración, encontrándose y distanciándose, según se le antoja a Ariosto; una tela que constituyen diversos hilos paralelos que hábilmente sabe tejer el autor.En cuanto al Orlando operístico (denominado más comúnmente en la época moderna, Orlando furioso) consta de tres actos con música de Antonio Vivaldi, basados en un libreto italiano de Grazio Braccioli, que a su vez es una “prolongación” del poema épico Orlando Furioso de Ariosto. La primera representación tuvo lugar en Venecia, en el Teatro Sant’Angelo, en otoño de 1727.La obra alterna arias con recitativos y está ambientada en una isla en un tiempo no especificado. La historia combina varios argumentos de Ariosto: desde las hazañas de Orlando hasta la historia de Alcina. Esta ópera, rara vez se representa en la actualidad.
Además de Vivaldi, el Orlando también fue tema de inspiración para otros compositores, como Haydn (Orlando Paladino. 1772), Piccinni (Roland. 1778), Handel (Alcina. 1735), Albinoni (Alcina Delusa da Ruggero 1725), Lully (Roland. 1685), Rossi (Il palazzo incantato. 1642), Caccini (La liberazione di Ruggiero dall’isola d’Alcina 1625), Méhul (Ariodant. 1799) o Mayr (Ginevra di Scozia. 1801).
De martes a sábado de 10 a 20h. Domingos y festivos de 10 a 14h. Último pase media hora antes del cierre. (foto: orlando, inauguraciòn)

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Brits Lie-in in Luxury

Posted by fidest press agency su sabato, 26 maggio 2012

English: Kingsdown Body Duet Mattress

English: Kingsdown Body Duet Mattress (Photo credit: Wikipedia)

London, (PRNewswire) The top five every day indulgences revealed by Feather & Black. An overwhelming 51% of Britons polled, cited a good quality mattress was their ‘must have’ every day indulgence in a recent survey conducted by luxury bedroom furniture company Feather & Black who had polled up to 2000 Brits. The survey revealed that faced with the doom and gloom of the current news agenda, Brits are choosing to treat themselves to a spot of every day luxury. The top five every day indulgences are:
Good quality mattress (51% of people polled)
Luxury bath or shower products (16%)
Goose or duck down duvet (11%)
Designer cushions or throws (11%)
High thread count bed linen (10%)
All respondents were huge advocates of a good quality mattress, but older 55+ respondents, were the biggest fans with 63% of them calling this their essential bedroom investment compared to 42% of 18 – 34 year olds. Younger respondees in comparison were bigger fans of luxury bathroom products and designer accessories, with 18% and 16% of them citing these respectively. Over 55’s are less enthusiastic 11% (luxury bath or shower products) and 8% (designer cushions or throws). Proof that the older we get, the more we seem to recognise the need for a luxurious mattress and a good night’s sleep.Adam Black, Managing Director of Feather & Black, says: “We would love to think that the British public are lying-in in luxury, thanks to our luxury mattresses and our accessories!”
Feather & Black is the ultimate destination for trends, inspiration and bedroom style with 35 stores nationwide. Be inspired by Feather & Black’s wooden beds, from classic shaker charm, to Parisian inspired elegance. With a rich heritage in iron bed design choose sculptured metal beds; or design your own iconic bed with Feather & Black’s beautiful bespoke upholstered beds. Feather & Black also have a selection of luxury pocket sprung mattresses made in the UK and personalised for your needs and budget. Complete the look with indulgent bed linen and dress your bed in luxurious textures with cashmere, wool and silk velvet accessories for a beautiful bed. Create a fun and stylish bedroom for the children too. ‘Feather & Black’s kids’ ranges offer everything you need to create a princess bedroom for girls or a base camp for boisterous boys.

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Women Make Sculpture

Posted by fidest press agency su martedì, 17 maggio 2011

Pangolin London 19th May – 18th June Kings Place, 90 York Way, N1 9AG Why are women still marginalised by the art world? Does gender bring something different to the work itself or is it just politics? These are some of the key questions that form the foundations of the exhibition Women Make Sculpture at Pangolin. Despite the huge success of a handful of sculptors such as Barbara Hepworth, Elisabeth Frink and Louise Bourgeois, women still find themselves under-represented in major ‘blockbuster’ shows. A prime example is the Royal Academy’s current exhibition Modern British Sculpture which has received so much criticism for leaving out established male sculptors such as Antony Gormley and Anish Kapoor. But what about the women? Is such a meagre selection really representative of the current state of British sculpture? Pangolin London thinks not.
Coinciding with the centenary year of International Women’s Day, Pangolin London will celebrate female achievement in sculpture with the exhibition Women Make Sculpture, an all female show highlighting the diversity and creativity of women sculptors today. The exhibition will bring into the spotlight a number of established female artists including Sarah Lucas, Dorothy Cross, Ann Christopher and Alison Wilding as well as emerging names such as Polly Morgan, Abigail Fallis, Rose Gibbs and Briony Marshall.
The exhibition will include an eclectic mix of work in a variety of media ranging from Almuth Tebbenhoff’s powerful yet intricate steel wall pieces to Polly Morgan’s delicate and fragile taxidermy constructions, and from Deborah van der Beek’s emotive horse head Collateral made from the detritus of war to Rose Gibbs’ controversial Mountain of figures and penises violently expelling bodily fluids.
Pangolin London is well-placed to do a survey show of this kind thanks to its unique affiliation with Europe’s largest sculpture foundry Pangolin Editions and its remit to promote sculpture in all its forms. Pangolin London will also host a panel discussion to coincide with the exhibition on Monday 23rd May at Kings Place. This will include both artists exhibiting in the show and guest speakers to encourage a lively debate. To book tickets please go towww.kingsplace.co.uk. (Dorothy Cross)

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2nd Herzliya Biennial for Contemporary Art

Posted by fidest press agency su sabato, 8 agosto 2009

Herzliya City Center 3-10 October 2009  The show will feature a large and diverse array of works, findings,  inventions and sounds from new Israeli art: sculptures, collages,  music, fashion, television, floristry, architecture, interior design,  astronomy, dance, theatre, martial arts, handicraft, cinema and  robotics – most of which will have their world premiere at the  biennial. These will be shown next to a refreshing selection of works  drawn from the history of Israeli art.  The list of participating artists includes a handful of young and  young-in-spirit artists, among them: Alber Elbaz (FR), Dani Gal (DE),  Pil and Galia Kollectiv (UK), Omer Krieger (IL), Nir Evron (IL), Benni  Efrat (IL), Anat Ben-David (UK), Keren Englman (IL), Amit Berlowitz  (IL), Idan Hayosh (NL), Tai Shani (UK), Freddy Kislev (IL), Noa  Giniger (NL), Yael Davids (NL), Avinat Gottesman (IL), Adam  Rabinowitz (LA), Ami Shavit (IL), Gilad Ratman (NYC), David Lieske  and Christian Naujoks (DE), Hillel Roman (IL), Eitan Ben-Moshe (IL),  Assaf Gruber (FR) and more. The opening event will be held in the presence of Mrs. Yael German,  mayor of Herzliya and initiator of the biennial, as well as  participating artists. http://www.e-flux.com/contact

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