Fidest – Agenzia giornalistica/press agency

Quotidiano di informazione – Anno 34 n° 271

Posts Tagged ‘society’

Comparing Landscapes. Art, nature and society in Switzerland

Posted by fidest press agency su giovedì, 30 settembre 2021

Bellinzona. From the second half of the 19th century until the First World War, society in Switzerland changed radically with industrialization and urbanization, the development of mobility and tourism. The landscape also underwent a transformation: the intensification of agriculture, nationalisation and the protection of forests modified its structure and appearance.The «beautiful Swiss landscape» no longer corresponds to the unspoilt ideal of the 18th century, but the nostalgia for this idyllic vision is combined with a desire for realism and modernity. Certainly, in artistic production, the oldest models always count, such as the Dutch views of the 17th century, as well as the trends emerging from the great European centres such as Paris and Munich. However, never have the friendships and cultural exchanges between Swiss painters been as important as they were then, for example the training of Bernese painter Ferdinand Hodler at Barthélemy Menn in Geneva or the stay of Basel-born Arnold Böcklin in Gottfried Steffan’s studio in Munich. By bringing the works of these artists into dialogue, the exhibition offers a rare opportunity to understand their relationships, which transcend regional borders, and to contemplate their landscapes with renewed wonder and awareness.With works by Cuno Amiet, Edoardo Berta, Arnold Böcklin, Alexandre Calame, Gustave Castan, François Diday, Hans Emmenegger, Filippo Franzoni, Otto Frölicher, Giovanni Giacometti, Jacques-Elie-Abraham Hermanjat, Ferdinand Hodler, Barthélemy Menn, Alexandre Perrier, Luigi Rossi, Giovanni Segantini, Johann Gottfried Steffan, Félix Vallotton, Robert Zünd and other artists.

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“Major support of democratic society”

Posted by fidest press agency su giovedì, 10 settembre 2020

Former Federal President Joachim Gauck acknowledges the achievements and commitment of HARTING / Festive celebration of the 75th anniversary of the Technology Group attended by many prominent guests.In view of a German society that would appear “satiated and fatigued in parts” (“the country’s spirit is on the brink”) as the former
headed of state commented, it is all the more remarkable to experience HARTING as decidedly and firmly looking to the future with courage, optimism and genuine joy, and bearing responsibility as “the most beautiful form of freedom.” Family owned and managed companies like HARTING are a “stable support of society”. Government cannot
replace their activities. In his speech, Dietmar Harting, the former long-standing Chairman of the Board of Management and son of the company founder, cast a look back on the beginnings of the company, which just a few months after
the end of the war had started to manufacture household appliances such as energy-saving lamps, hotplates, lighters, waffle irons and irons in a small workshop and a dozen employees. The company’s first buyer brought raw materials in from the Rhineland, stowed away in a backpack while riding a coal waggon; the wife of the company founder delivered the company’s
goods by bicycle, accepting food as payment from farmers in the surrounding area. The young firm developed rapidly, soon
concentrating on automotive electrics, medical equipment, jukeboxes, record players and tape recorders. With the advent of the patented Han® connectors in 1956, the company, which was gradually relocated to neighbouring Espelkamp from the 1950s onwards, went on to write technology history. The mayors of the cities of Minden and Espelkamp, Michael Jäcke and
Heinrich Vieker (“Espelkamp would not be conceivable without HARTING”), the District Administrator of the Minden-Lübbecke district, Dr. Ralf Niermann, as well as the District President of Detmold, Judith Pirscher, emphasized HARTING’s role in the technology sector, as an attractive employer and leading-edge, ultra-modern training company, and as a promoter and generous supporter of the region in their welcome addresses. The musical accompaniment of the ceremony was by members of the NorthwestGerman Philharmonic Orchestra and the New Life Gospel Choir.The last highlight rounding up the exceptional festive day was a short reception of the former Federal President in the town hall of Espelkamp, where he signed the Golden Book. More information at

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Meeting annuale 2020 della American Society of Clinical Oncology (ASCO)

Posted by fidest press agency su mercoledì, 20 Maggio 2020

Foster City (California) e Santa Monica (California) Si terrà dal 29 al 31 maggio 2020. I dati degli abstract per il meeting ASCO includono le terapie cellulari frutto dell’impegno in R&D di Kite, cui si aggiunge magrolimab, un anticorpo monoclonale sperimentale anti-CD47 sviluppato da Forty Seven, Inc., l’azienda recentemente acquisita da Gilead. I risultati aggiornati di uno studio di fase Ib condotto con magrolimab in pazienti con sindrome mielodisplastica (MDS, myelodysplactic syndrome) e con leucemia mieloide acuta (LMA) – inclusi pazienti con LMA con mutazioni P53, fortemente bisognosi di una cura – saranno al centro di una presentazione orale (Abstract #7507). Inoltre, i nuovi dati sulle terapie cellulari con recettore antigenico chimerico delle cellule T (CAR-T) comprendono un’analisi intermedia dei dati dello studio di fase II ZUMA-5, che sta valutando l’utilizzo sperimentale di axicabtagene ciloleucel in pazienti con linfoma non Hodgkin indolente (iNHL, indolent non-Hodgkin lymphoma) recidivante o refrattario. Questi dati saranno anche presentati in una sessione orale (Abstract #8008).
Per ulteriori informazioni – incluso l’elenco completo dei titoli degli Abstract presentati nel corso del Meeting – visitare:

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73º Convegno della Society of Cosmetic Chemists

Posted by fidest press agency su mercoledì, 25 dicembre 2019

Nel 2019 Mary Kay Inc. ha perseverato nel suo impegno decennale verso la ricerca scientifica sulla cura della pelle rivelando i risultati di diversi studi rivoluzionari e promuovendo il dibattito accademico tra gli esperti del settore presso simposi scientifici in tutto il mondo. Recentemente Mary Kay si è recata a New York per partecipare al 73° convegno della Society of Cosmetic Chemists, dove il marchio ha sponsorizzato, collaborato ed esplorato applicazioni basate sul microbioma cutaneo insieme a rinomati esperti del campo.
“Dalle nuove ricerche è emerso che i microorganismi svolgono un ruolo importante per la salute generale della pelle e, quale leader nell’innovazione della cura della pelle, Mary Kay ha effettuato ingenti investimenti per esplorare ancora più a fondo il loro impatto” ha affermato la D.ssa Lucy Gildea, Direttore scientifico presso Mary Kay. “Parte del nostro impegno sta nell’assumere un ruolo attivo nelle comunità scientifica e della cosmesi partecipando a conferenze di carattere globale dedicate alla dermatologia, come il convegno della Society of Cosmetic Chemists, in cui possiamo condividere le nostre conoscenze con altri esperti scientifici, nonché apprendere da loro per poter sviluppare prodotti più efficaci e innovativi.” Il convegno Society of Cosmetic Chemists accoglie più di 1.300 partecipanti appartenenti ai brand e ai produttori tra i più prestigiosi nel mondo della cosmesi e della cura della persona. I partecipanti sono incoraggiati a interagire con i relatori che presentano i risultati delle ultime ricerche e innovazioni di interesse per gli scienziati del campo della cosmesi, così come a scambiare idee con i loro colleghi e a riconnettersi con colleghi provenienti da tutto il mondo.

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61st American Society of Hematology Annual Meeting

Posted by fidest press agency su domenica, 17 novembre 2019

ALX Oncology, a clinical-stage immuno-oncology company developing therapies to block the CD47 checkpoint mechanism, today announced that ALX148 clinical results have been selected for presentation at the 61st ASH Annual Meeting & Exposition, December 7 – 10, 2019, Orange County Convention Center, Orlando, FL.“This year’s ASH meeting will be an opportunity to provide important clinical updates on our CD47 program in hematologic malignancies,” said Sophia Randolph M.D., Ph.D., Chief Medical Officer of ALX Oncology. “We are excited to share the first clinical efficacy data from the combination of ALX148 with rituximab, showing that ALX148 maximizes clinical activity with a best-in-class safety profile. We are committed to further development of this agent with the potential to transform standards-of-care for patients with cancer.”

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American Society of Clinical Oncology’s Annual Meeting

Posted by fidest press agency su sabato, 1 giugno 2019

Today, Sarah Cannon announced that it will present its latest cancer research insights through more than 100 abstracts and presentations at the American Society of Clinical Oncology’s (ASCO®) Annual Meeting hosted in Chicago, from May 31-June 4, 2019. The ASCO® Annual Meeting brings together more than 40,000 cancer experts from around the world to review the latest research and discuss this year’s theme of “Caring for Every Patient, Learning from Every Patient.” Sarah Cannon experts will participate in a number of presentations and educational sessions focused on immunotherapies, including cellular therapy, and targeted investigational agents that are transforming the delivery of cancer care for patients.“The research presented at this year’s Annual Meeting will highlight Sarah Cannon’s involvement in the latest CAR T-Cell Therapy approaches, bispecific antibodies, novel targeted therapies as well as personalized cancer vaccines. We continue to be excited about the developments being made in individualized cancer therapies and the potential impact for patients worldwide,” said Howard A. “Skip” Burris, III, MD, President of Clinical Operations and Chief Medical Officer at Sarah Cannon. Dr. Burris will serve as the ASCO® President for the 2019-2020 term, and will be inducted into his position on Monday, June 3, during the Annual Meeting.A number of Sarah Cannon’s presentations will focus on insights from more than 50 phase 1 studies, which include novel immunotherapy combinations and CAR T-Cell, as well as mutation-targeted agents.An oral presentation titled “Safety and Preliminary Antitumor Activity of U3-1402: A HER3-Targeted Antibody Drug Conjugate in EGFR TKI-Resistant, EGFRm NSCLC,” will feature the work of Melissa Johnson, MD, an investigator on the trial. Additionally, Sarah Cannon’s work, under the leadership of Gerald Falchook, MD, on the phase I trial investigating the targeted therapy KRASG12C will be highlighted in an oral presentation at the meeting. The phase 1 dose escalation study of the ERK inhibitor LY3214996 will also be highlighted in an oral presentation, featuring the work of Johanna Bendell, MD, and Manish Patel, MD.
Lowell Hart, MD, will highlight the latest in novel biologics through an oral presentation on the “Effect of Trilaciclib, a CDK 4/6 Inhibitor, on Myelosuppression in Patients with Previously Treated Extensive-Stage Small Cell Lung Cancer Receiving Topotecan.” Sarah Cannon’s work in cellular therapy, under the leadership of William Donnellan, MD, will be showcased in an oral presentation on the phase I results of KTE-X19 in adult patients with relapsed/refractory acute lymphoblastic leukemia.

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“Church, Disability and Society”

Posted by fidest press agency su sabato, 13 aprile 2019

The Pan-Hellenic Conference with an international participation was successfully held in Volos on the general theme: “Church, Disability and Society.” The conference was organized by the Volos Academy for Theological Studies in cooperation with the Holy Metropolis of Demetrias, the charitable company “Health Path” and the Association of People with Disabilities in Magnesia, “Ippokampos”. The topic in question attracted the interest of teachers, scientists, students, people with disabilities and citizens who are aware of and active on this issue.
The conference presentations addressed a variety of themes: a) “Psycho-social dimension of disability,” b) “Practices of integration and accessibility of persons with disabilities in the liturgical texts and the body of the Church,” c) “Orthodox theology and disability.” In the first session Dr. Galini Sapountzaki (Sign Language Linguist, Assistant Professor of Special Education, Department of Special Education, University of Thessaly) spoke on the topic “Self-identification and self-image of people with hearing impaired problems”; Dr. Ioulia Nissiotou (Paediatrist, Assistant Professor, Department of Special Education, University of Thessaly) presented the topic “The Doctor as a companion of the disabled child and his/her parents;” while Ioanna Georgiadou (Social Clinic Psychologist MSc, Systemic Psychotherapist, PhD Candidate of the University of Thessaly) spoke on “Self-assistance and empowerment of people with mobility disabilities.”
During the second session the first speaker, Rev. Anargyros Sigalas (Parish Priest, Agioi Pantes Church Kallithea, Athens) presented a paper on “Deaf hearings…meaningful: the example of the parish of deaf people, while Rev. Dr. Konstantinos Papanikolaou (Former Director of IEA, Member of the EASPD Standing Committee on Employment) spoke on the topic “OLYMPIAS, Facilitating the access of people with disabilities to the Church and work through the Internet.” A round table discussion also took place during the conference on the topic “Church and Disability: Obstacles and Bridges” with the participation of Petros Bellos (President of the Association of People with Disabilities in Magnesia, “Ippokampos”), Ioanna Georgiadou (Social Psychologist, Msc, Systemic Psychotherapist), Rev. Georgios Giannos (Parish Priest, The Dormition of the Mother of God church, Metropolis of Demetrias, Member of the writers team of the book manual, “The Religious Lesson in Special Education”), and Dr. Christiana Lappa (Post-doctoral Researcher in Special Education, University of Thessaly, Lecturer at the Hellenic Open University). During the conference all the papers were presented in the sign language while the closing of the conference took place in the morning of Sunday, March 31, with the Divine Liturgy at the Church of Evangelistria in Nea Ionia, Volos, which was also presented in the sign language.

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ERYTECH Presents Findings at European Red Cell Research Society Meeting

Posted by fidest press agency su venerdì, 15 marzo 2019

LYON, France and CAMBRIDGE, Mass., (GLOBE NEWSWIRE) — ERYTECH Pharma (Euronext Paris: ERYP – Nasdaq: ERYP), a clinical-stage biopharmaceutical company developing innovative therapies by encapsulating drug substances inside red blood cells, announced that an oral presentation entitled “Comprehensive proteomic profiling of erythrocytes following hypotonic dialysis-based drug encapsulation process“ will be presented today at the 22nd meeting of the European Red Cell Research Society (ERCS) in Ascona, Switzerland. A poster highlighting the results of this work will also be presented at the ERCS Meeting and will be available on the Company’s website at after March 11, 2019.The lead investigational therapeutic produced using the Company’s ERYCAPS® encapsulation process, eryaspase, consisting of the enzyme L-asparaginase encapsulated inside donor-derived red blood cells, is currently being evaluated in the Phase 3 TRYbeCA-1 trial in metastatic pancreatic cancer. In an earlier 141 patient randomized Phase 2b trial of eryaspase in combination with chemotherapy for the treatment of second-line metastatic pancreatic cancer, significant improvements in overall survival and progression free survival were observed versus chemotherapy alone with no apparent increase in toxicity2.
The erythrocyte proteomic profiling study being presented at the meeting was performed with the participation of the 3P5 Proteomic Platform (at the Paris-Descartes University, France) specialized in high-performance mass spectrometry protein identification and microanalysis. With the exception of L-asparaginase, profiling analysis revealed no significant difference in the proteomic landscape when comparing packed RBCs, ERYCAPS®-processed RBCs without enzyme, and ERYCAPS®-processed RBCs encapsulating L-asparaginase.These results confirm the notion that the ERYCAPS® process does not significantly alter the properties of RBCs and that apart from the encapsulated drug substance, RBC-based therapeutics produced using this process have similar characteristics to that of unprocessed packed RBCs.
ERYTECH plans to advance candidates using the ERYCAPS® platform and to explore the field of RBC-based therapeutics, building on these proteomic results and future findings regarding RBC biology.

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AM Best Withdraws Credit Ratings of The Education Benevolent Society Incorporated

Posted by fidest press agency su domenica, 6 gennaio 2019

AM Best has withdrawn the Financial Strength Rating of B++ (Good) and the Long-Term Issuer Credit Rating of “bbb” of The Education Benevolent Society Incorporated (EBS) (New Zealand) as the company has requested to no longer participate in AM Best’s interactive rating process.On December 31, 2018, EBS completed a portfolio transfer that resulted in all existing insurance obligations at the company being transferred to Union Medical Benefits Society Limited. From January 1, 2019, EBS no longer operates as an insurance company and acts as a marketing organization.AM Best’s procedure is for a final rating opinion to be produced in conjunction with a rating withdrawal. However, because EBS’ balance sheet does not contain any insurance assets or liabilities, AM Best was unable to produce a final rating opinion.
Ratings are communicated to rated entities prior to publication. Unless stated otherwise, the ratings were not amended subsequent to that communication.AM Best is a global rating agency and information provider with a unique focus on the insurance industry. Visit for more information.

Posted in Economia/Economy/finance/business/technology, Estero/world news | Contrassegnato da tag: , , | Leave a Comment »

Conscious citizenship: new Maltese citizens give back to society

Posted by fidest press agency su mercoledì, 1 agosto 2018

Chetcuti Cauchi Advocates. Claris Foundation, Chetcuti Cauchi Advocates’ philanthropic arm, inaugurated the reconstruction of a state-of-the-art playground at a children’s home in Malta. This charitable event was officially endorsed by Hon Julia Farrugia Portelli, Parliamentary Secretary for Reforms, Citizenship and Simplification of Administrative Processes.Chetcuti Cauchi Advocates has always been conscious of less fortunate people and willing to devote time and money to give back to society. Thanks to the firm’s commitment to charitable giving and the generosity of its high-net-worth investor clients, Claris Foundation has managed to allocate €70,000 of its funds for the installation of a fully-equipped and modern play area with the aim of providing the children with a safe environment for play, leisure and interaction.Lead partner of the firm’s Residency and Citizenship Practice Group and a member of the Board of Administrators of Claris Foundation, Dr Jean-Philippe Chetcuti encourages aspiring Maltese citizens to contribute towards Claris Foundation. In Dr Chetcuti’s words, “The goal of the Programme is not to accept as many new Maltese citizens as possible; rather, it strives to attract talented individuals of an excellent standing that can contribute not only to our economy but also to the social well-being of the country. For instance, some of our clients have invested in promoting Maltese art abroad; but many contribute to approved charities such as Claris Foundation helping underprivileged children and refugees.”Dr Chetcuti also added that the willingness to give back is relatively common amongst high-net-worth investors we work with, with some 91% of the firm’s international client families supporting a charity of their choice.These views are shared by Hon Julia Farrugia Portelli, who inaugurated the completion of the playground. Hon. Portelli Farrugia observed that “since the inception of the citizenship by investment programme, more than 550 donations have been made by applicants of the programme, with an overwhelming value of €3.5 million.” The positive impact of the programme, according to Ms Farrugia Portelli, is “measured not through monetary means, but through the legacy it is leaving behind.”Dr Maria Chetcuti Cauchi, Chairperson of Claris Foundation and co-founding partner of Chetcuti Cauchi Advocates, joined them in expressing her gratitude towards the international investor community, explaining that donations to Claris Foundation used to previously come from the employees and their family members, however, foreign clients have voluntarily joined them in this mission. “It is through the generosity of such persons as well as the hard work carried out by the employees that this initiative has become a reality,” stated Dr Chetcuti Cauchi at the playground inauguration ceremony.It is also worth mentioning that the philanthropic efforts of the firm, coupled with the generosity of international benefactors, have allowed Claris Foundation to realise a number of other charitable projects, including funding children education under the Jesuit Refugee Services Integration Programme, reconstructing a family home in Albania, and covering the costs of the psychological examination for a student in need. Claris Foundation is a Malta-based charitable organisation established in 2008 with the scope of raising awareness about vulnerable persons in Malta and abroad, as well as for developing and implementing programmes in support of health, education and well-being of children worldwide. Projects embarked on by Claris Foundation include the reconstruction of a family’s home in Albania, financial assistance for a student’s psychological examination, as well as supporting the Jesuit Refugee Services Integration Programme.

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Internet Society Names Andrew Sullivan as New President & CEO

Posted by fidest press agency su domenica, 1 luglio 2018

In advance of its 2018 Annual General Meeting, the Internet Society’s Board of Trustees announced today that it has selected Andrew Sullivan as the organization’s new President and Chief Executive Officer. Sullivan will assume leadership of the global non-profit organization dedicated to promoting the open development, evolution and use of the Internet on 1 September, 2018. As President and CEO, Sullivan will also join the Internet Society’s Board of Trustees.
Sullivan brings many years of experience in the Internet industry to his new role, having worked to enhance the Internet’s value as an open, global platform throughout his career. Among his notable achievements is the launch of the .info Internet top level domain name. While at Dyn, now a Global Business Unit of the Oracle Corporation, he managed the Domain Name System (DNS) development and architecture departments. This led to his appointment to the Internet Architecture Board (IAB) – which oversees the technical evolution of the Internet – where he was elected Chair from 2015-2017.“The Board and I are extremely pleased that Andrew will be leading the Internet Society forward,” said Gonzalo Camarillo, Chair of the Internet Society Board. “Our current President & CEO, Kathy Brown, has laid the foundation for Andrew to increase the Internet Society’s relevance and impact in shaping the future of the Internet. We are confident that he will succeed in leading the organization and its community in working for a more open, globally-connected, secure, and trustworthy Internet for everyone.”With nearly half the world’s population still lacking Internet access, Sullivan will use his new role to address the growing opportunities gap that is opening up between those who have access and those who don’t. “The Internet is now central to so many people’s lives, and world events make the mission of the Internet society more important than ever before,” said Andrew Sullivan. “It is only together that we can ensure that the Internet keeps fulfilling its promise to enrich people’s lives and I can think of no better way to deliver on that promise than as President & CEO of the Internet Society. I am honoured to have been chosen for this role, and will work every day to promote the defining values of an open, trusted Internet.”Sullivan holds a Bachelor of Arts (Hons) from the University of Ottawa, and a Master of Arts degree from McMaster University. His graduate work on the philosophy of economics led him to his interest in free and open source software and open Internet protocols and standards. He now carries that interest and passion forward to his new position at the Internet Society.He will be based in Reston, Virginia.

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World Congress of the International Cartilage Repair Society

Posted by fidest press agency su martedì, 10 aprile 2018

Macau Room Almaty 3, Sheraton Grand Macau Hotel Tuesday, April 10, 2018 12:30 – 13:30 Almaty 3 Room, Lunch Symposium: HYALOFAST One-step Procedure: Best Practice and New Evidence in Cartilage Repair. Moderator: Alberto Gobbi, OASI Bioresearch Foundation, Milano – Italy Speakers: Dr. Bogusław Sadlik, St. Luke Hospital – Bielsko Biala – Poland, Dr. Alberto Gobbi, OASI Bioresearch Foundation, Milano – Italy, Prof. Stephan Nehrer, Danube University, Krems – AustriaAnika Therapeutics, Inc. (NASDAQ: ANIK), a global, integrated orthopedics and regenerative medicines company specializing in therapeutics based on its proprietary hyaluronic acid (“HA”) technology, today announced plans to showcase HYALOFAST®, a biodegradable, HA-based cartilage repair scaffold, at the 14th World Congress of the of the International Cartilage Repair Society (ICRS). The ICRS World Congress, which is being held in Macau, China during April 9-12, 2018, is the world’s largest gathering of scientists, clinicians and industry participants focused on clinical cartilage repair and basic cartilage research.
“HYALOFAST represents a major advancement in the treatment of cartilage injuries and defects, evidenced by the positive reception it has received from physicians across 15 global markets,” said Joseph Darling, President and CEO, Anika Therapeutics. “The ICRS World Congress is the ideal venue to showcase the significant advantages HYALOFAST offers over invasive open surgical techniques and traditional scaffolds, to the largest gathering of cartilage repair specialists from around the world. At this year’s meeting, we’ve developed a robust educational agenda featuring world-renowned thought-leaders with HYALOFAST expertise sharing their technical know-how and providing hands-on, guided training sessions with our custom-built HYALOFAST Virtual Surgical Simulator. We believe that peer-to-peer education and technical training is central to prompting the HYALOFAST trial, which we hope will increase commercial adoption.”
HYALOFAST is a non-woven, single-step, off-the-shelf, biodegradable HA-based scaffold for hyaline-like cartilage regeneration to treat cartilage injuries and defects. HYALOFAST is commercially available in over 15 countries and has been used to successfully treat more than 14,000 patients internationally, and with strong five-year patient follow-up data. HYALOFAST is pending regulatory submission in the United States and its FastTRACK Phase III trial is currently enrolling patients across the U.S. and Europe.

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Smithers Avanza Toxicology Services to Offer Two Presentations at 2018 Society of Toxicology Annual Meeting

Posted by fidest press agency su martedì, 13 marzo 2018

Smithers Avanza Toxicology Services, a contract research organization (CRO) supporting the pharmaceutical and chemical industries, will offer a presentation and poster at this year’s Society of Toxicology (SOT) Annual Meeting to be held March 11-15 in San Antonio, Texas. In addition, several representatives from Smithers Avanza Toxicology Services will be on hand to talk with attendees at booth #1123 in the exposition center.“It’s always an honor to share our information, with industry colleagues and clients,” said Michael Dorato, PhD, DABT, Fellow ATS, Executive Vice President, Smithers Avanza Toxicology Services. “The annual meeting always provides numerous opportunities to share data and best practices while connecting with experts from all over the world.” Dr. Shakil Saghir, Principal Toxicologist, Smithers Avanza Toxicology Services, will present “Use of KMD in Regulatory-Mandated Toxicity Testing of Non-Pharmaceuticals: From Concept to Application” at the roundtable session on Wednesday, March 14 at 4:30 p.m. Smithers Avanza will also feature the poster presentation “Geriatric Toxicology: Understanding Human Relevance of Toxicities Observed at Late-Stage of Long-Term Studies” (Poster Board #P709 in the Exhibit Hall), authored by Dr. Shakil Saghir and Dr. Michael Dorato. Dr. Saghir will be on hand to discuss the poster.For more information about the Smithers Avanza portfolio of services, visit

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There is a growing consensus that current narratives around poverty have failed and that a new approach is needed to create a good society

Posted by fidest press agency su venerdì, 28 ottobre 2016

londraLondra. One that requires collective action from government, charities, business and communities and which is willing to try new ways of working. This was the message to come out of an event and special report, organised by the Webb Memorial Trust.
Andrew Curtis, senior programme manager at Oxfam, said: “There is growing consensus that the narratives used in the third sector, however well-meaning and right, have been rejected. Poverty is a term that is politically divisive, creates stigma and is highly contested to the point of still having to persuade people that poverty exists in the UK. We need to create a new way of speaking, to speak with those directly affected not for them, and we need to speak louder.” Olivia Bailey, research director at the Fabian Society, said: “Language matters. Talking about poverty describes the problem but it doesn’t generate enthusiasm for solutions. We need to find a new framework that is a rallying point for people to get behind a raft of policies. The American Dream tapped into that aspiration. We should think about the ‘British Promise’, which should be the security to know if you need help it is there.” Dr Michael Orton, Warwick University Institute for Employment Research, said: “A shared vision means not working in silos. It means consensus building. Working together should be at the core of what we do. Instead of launching into ideological deconstructions of that vision, we should [each] focus on the bits that we can work with.”Rys Farthing, a social policy analyst who specialises in youth and poverty, said: “Our ways of trying to create a world without poverty have been tried and tested and got us this far. We need to try every tactic we can think of to keep winning. Working with children and young people as a solution is a strategy we haven’t tried much yet. It might be a way to find some new pathways to progress.”

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Close the gaps on fundamental inequality

Posted by fidest press agency su venerdì, 24 giugno 2016

pianeta terraGovernments must act now to address economic and social inequalities that divide people and countries, benefiting only a few and forcing the many into cycles of poverty, vulnerability and marginalization, international humanitarian and development network ACT Alliance has said. Commenting as the World Wealth Report from CapGemini was released today, ACT Alliance said that there is an urgent need for governments to close the gap by promoting policies known to lower income and wealth disparities.“Ending inequalities between countries and between people represents addressing issues of justice, issues of human rights, and issues that speak to the kind of society that people want to live in,” said John Nduna, ACT Alliance General Secretary. Questioning the existing economic model, Nduna said: “We need a new paradigm that addresses the root causes of poverty, and policies that offer pathways to progressive taxation and greater wealth distribution.”While there is an unprecedented trend in increasing income inequality within countries for the benefit of a few mega rich individuals, ACT Alliance highlighted that social protection programmes, progressive taxation and equity based structural policies such as the introduction of a minimum wage could play a significant role in reducing the growing gap between rich and poor. ACT Alliance is a coalition of 140 churches and faith-based organisations working together in over 100 countries to create positive and sustainable change in the lives of people in need. ACT works through faith-based networks and communities to help inform and influence justice and rights-based policies at all levels that seek to address the existing gaps in income and other forms of inequality. “Action today could mean that specific targets for equity could be achieved,” said Nduna. “For example, enhanced use of progressive taxation on business, foreign investments, income and wealth, or securing full and productive decent work for all, could have rapid impacts on people most in need. Closing these gaps requires intentional commitments by political leaders, business leaders and ambitious policies from governments at all levels. Without this, there will be no end to the broken economic system that makes a few rich and the majority poor.”
ACT Alliance is part of the Fight Inequality Alliance a group of organisations including ActionAid, Amnesty International, CIVICUS, Femnet, Focus on the Global South, Greenpeace, International Trade Union Confederation (ITUC) and Oxfam.

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Wrong and outdated views towards LGBT people endanger their fundamental rights

Posted by fidest press agency su mercoledì, 16 marzo 2016

fundamental rightsIn some Member States, doctors still view homosexuality as a disease and transsexuality as a mental disorder, according to findings from a new report by the EU Agency for Fundamental Rights (FRA). Such negative views of lesbian, gay, bisexual and trans (LGBT) people in society, among professional groups and policy makers hampers efforts to counter discrimination and hate crime. In the first-ever comparative survey across 19 Member States of the views of public officials, health officials, teachers and police officers, the positive impact of EU initiatives were largely acknowledged. However, they also recognised the lack of information and professional training about the needs of LGBT people prevents them from acting to help counter the discrimination LGBT people continually face.
“LGBT people have the same rights to education, to healthcare and to be treated equally as everyone else. They too have the right to live their life in dignity, free from fear and discrimination,” says FRA Director Michael O’Flaherty. “FRA’s latest findings reveal how some doctors still wrongly believe that homosexuality is a disease. They underscore the need for the EU and its Member States to empower public officials to act on their duty to deliver high quality service to help end the suffering many LGBT people experience.”FRA spoke to the professional groups best placed to identify the barriers and drivers in implementing fundamental rights policies on the ground. Some of the key findings that conseil de l'europeemerged that can be found in the ‘Professionally speaking: challenges to achieving equality for LGBT people’ report include:Society can be hostile view towards LGBT people and professionals can harbour prejudices, such as believing that homosexuality is a disease that can be caught. This points to the need for more positive EU and national awareness-raising campaigns, such as in the EU’s list of actions to improve respect for LGBT people and their rights. All professional groups have low levels of awareness and knowledge about LGBT needs. This underlines the importance of professional training, and civil society partnerships and cooperation to help counter prejudice, especially towards trans people in healthcare, and better deliver the same high level of service that most other people enjoy.The lack of objective information, particularly in schools, can result in bullying and prejudice in later life, and force LGBT youths to hide their sexual orientation/ gender identity. Member States should work with education authorities and schools to formulate targeted campaigns to help make schools a safer and friendlier place for LGBT people.LGBT hate crime often goes unrecognised, unreported and unrecorded. Member States should make more efforts to ensure the laws guarding against hate crime are properly enacted, and that greater efforts are made to improve LGBT hate crime reporting which should be recorded.
The report surveyed public officials, doctors, teachers and police officers about which laws and policies work and which do not, and why, when it comes to protecting and promoting the rights of LGBT people. A comprehensive EU-wide overview of LGBT-relevant laws and policies can be found in a FRA report launched in December 2015. This report also looks at the problems intersex people face.The findings complement the results from FRA’s ground-breaking EU LGBT survey which revealed large-scale fear and discrimination among LGBT people across the EU. The full dataset from the survey will be available later this year.
The EU Agency for Fundamental Rights (FRA) provides evidence-based advice to EU and national decision makers, thereby contributing to more informed and better targeted debates and policies on fundamental rights.

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Alternatives to detention for asylum seekers and forced-return procedures

Posted by fidest press agency su domenica, 11 ottobre 2015

alternativesIn the context of its work in the area of migration, asylum and borders, FRA is today publishing a new paper, Alternatives to detention for asylum seekers and people in return procedures. The paper seeks to provide guidance to policy makers and practitioners on the use of measures for asylum seekers and people in return procedures that do not unnecessarily deprive them of their right to liberty.
Making use of the many alternatives to detention is of advantage both to the hosting state and migrants, as on the one hand they are more cost-effective and on the other they are less intrusive and more respectful of fundamental rights. According to the UN Special Rapporteur on the human rights of migrants, alternatives are far less expensive than detention, not only in the short term but also when it comes to longer-term costs associated with detention, such as the impact on health services or on the integration of migrants into EU society.
For asylum seekers as well as those already on EU territory whose applications for international protection or residence permits have been rejected, detention too often remains the default solution. At the same time, the majority of EU Member States provide for the possibility of alternatives to detention. This FRA paper discusses a number of such alternatives, and lists a number of legal and other instruments together with the general human rights and EU legal framework.The first section of the paper covers the international framework that safeguards the right to liberty, while the following sections focus specifically on alternatives to detention as follows:
Selected instruments on the right to liberty
Selected non-binding United Nations instruments on alternatives to detention
Selected non-binding Council of Europe instruments on alternatives to detention
Selected European Union law provisions relating to alternatives to detention
Selected case law from the European Court of Human Rights, the Court of Justice of the EU and the United Nations Human Rights Committee on alternatives to detention
Recently developed tools
Selected research publications (photo alternatives)

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Fundamental rights and non-discrimination conference in Tirana – final statement

Posted by fidest press agency su lunedì, 24 novembre 2014

tiranaTirana. At the end of the conference on “Fundamental rights, non-discrimination and the protection of vulnerable groups, including LGBTI”, which took place in Albania on 20-21 November 2014, the participating Members of the European Parliament, the Italian Presidency of the Council of the EU and the European Commission issued the following statement:”This conference has shown that enlargement countries have put in place key elements of the legal and policy framework for fundamental rights and non-discrimination. Vulnerable groups, among them LGBTI citizens, nonetheless often remain at risk of discrimination, marginalization or even violence. We encourage governments and political leaders of the region to demonstrate their commitment to ensuring that all minorities and vulnerable groups are accepted and can participate freely in society. They should also ensure that discrimination on the basis of sexual orientation and gender identity is prohibited in law and that persons belonging to minorities can equally exercise their rights. A hierarchy of grounds must be avoided and attention should be paid to multiple forms of discrimination. Finally, sustained efforts are needed to implement and enforce relevant legislation and policies, to adopt pending reforms and to work at changing societal attitudes from prejudice and even hostility to respect and acceptance.”

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Bloccare la proteina TRF2

Posted by fidest press agency su venerdì, 21 novembre 2014

Cancro-sintetizzata-molecola-che-blocca-proteina-tumoraleTRF2 è una proteina strutturale delle regioni terminali dei cromosomi (telomeri), che gioca un ruolo importante nel processo di trasformazione neoplastica. Bloccarla può rappresentare una nuova e valida strategia antitumorale. Un gruppo di ricercatori dell’Istituto Regina Elena (IRE) di Roma, coordinato da Annamaria Biroccio, ha sintetizzato un piccolo peptide in grado di interrompere i segnali cellulari ad attività tumorale di TRF2. Il lavoro è stato pubblicato oggi sulla rivista internazionale Journal of American Chemical Society.
Il progetto multidisciplinare nasce dalla collaborazione con i Chimici dell’università Federico II di Napoli e si fonda sull’osservazione che la proteina TRF2, attraverso il suo dominio TRFH è in grado di convogliare al telomero varie proteine che contribuiscono con la loro attività alla formazione del tumore. I ricercatori, basandosi su dati cristallografici disponibili in letteratura, hanno disegnato e sintetizzato un peptide che, legandosi con alta affinità al dominio TRFH di TRF2, inibisce i segnali coinvolti nel processo di tumorigenesi. Tale molecola non è stata scoperta per caso, ma tramite processi di ingegneria chimica, che hanno permesso la modulazione della sua funzionalità e l’ottimizzazione di determinate proprietà, allo scopo di trovare la molecola giusta.
Questi studi rappresentano il futuro della ricerca. “La bioinformatica – chiarisce Annamaria Biroccio – e nello specifico gli studi predittivi, permetteranno di ottimizzare quei processi che intercorrono tra la fase di ‘disegno’ e quella di selezione dei farmaci a bersaglio molecolare e permetteranno, conseguentemente, di abbattere i tempi e, non ultimo, i costi legati alla sperimentazione.”
“Le moderne tecniche di Rational Design e l’utilizzo di modelli bioinformatica- spiega Pasquale Zizza, primo autore dello studio – hanno consentito il disegno e la selezione di una molecola ad elevato potenziale applicativo in grado di bloccare le funzioni reclutanti di TRF2.”
“I risultati ottenuti – evidenzia Annamaria Biroccio – scaturiscono da uno studio più ampio, in collaborazione con il gruppo francese diretto dal Prof. Eric Gilson, in cui è stato identificato un ruolo non canonico della proteina telomerica TRF2. Il lavoro pubblicato sulla rivista “Nature Cell Biology” a Luglio del 2013, infatti, evidenziava come TRF2 possa contribuire allo sviluppo tumorale, non solo attraverso la sua già nota capacità di mantenere l’integrità telomerica, ma anche attraverso la modulazione di alcuni componenti del sistema immunitario.”“Lo studio appena pubblicato – sottolinea Ruggero de Maria, Direttore Scientifico IRE -rappresenta un esempio di come attraverso un approccio multidisciplinare sia possibile in tempi rapidi passare dall’identificazione di un bersaglio molecolare al disegno di un inibitore specifico.”

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Action needed to ensure that all people with disabilities can vote

Posted by fidest press agency su martedì, 29 aprile 2014

european votePeople with disabilities are active citizens keen to participate in political life given the right opportunities. However, legal, administrative and accessibility barriers can still prevent them from taking part in elections finds the latest research on the rights of people with disabilities from the EU Agency for Fundamental Rights (FRA).“Political participation is a basic right that everyone should enjoy equally,” says FRA Director Morten Kjaerum. “Yet, FRA’s report underlines that many barriers can undermine the democratic rights of people with disabilities. With European elections around the corner, it is timely reminder that across the EU change is needed to allow all people with disabilities to have an equal say in the political life of our society.”Together with the European Commission, FRA developed a set of human rights indicators on how the right to political participation, as described in the UN’s Convention on the Rights of Persons with Disabilities (CRPD), is being respected, promoted and fulfilled across the EU. The data which populate these indicators show that given the opportunity people with disabilities actively participate in politics through voting, political meetings and engaging with elected officials. However, the data also reveal that significant challenges remain which affect some people with disabilities more than others.

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