Fidest – Agenzia giornalistica/press agency

Quotidiano di informazione – Anno 31 n°159

Posts Tagged ‘society’

“Church, Disability and Society”

Posted by fidest press agency su sabato, 13 aprile 2019

The Pan-Hellenic Conference with an international participation was successfully held in Volos on the general theme: “Church, Disability and Society.” The conference was organized by the Volos Academy for Theological Studies in cooperation with the Holy Metropolis of Demetrias, the charitable company “Health Path” and the Association of People with Disabilities in Magnesia, “Ippokampos”. The topic in question attracted the interest of teachers, scientists, students, people with disabilities and citizens who are aware of and active on this issue.
The conference presentations addressed a variety of themes: a) “Psycho-social dimension of disability,” b) “Practices of integration and accessibility of persons with disabilities in the liturgical texts and the body of the Church,” c) “Orthodox theology and disability.” In the first session Dr. Galini Sapountzaki (Sign Language Linguist, Assistant Professor of Special Education, Department of Special Education, University of Thessaly) spoke on the topic “Self-identification and self-image of people with hearing impaired problems”; Dr. Ioulia Nissiotou (Paediatrist, Assistant Professor, Department of Special Education, University of Thessaly) presented the topic “The Doctor as a companion of the disabled child and his/her parents;” while Ioanna Georgiadou (Social Clinic Psychologist MSc, Systemic Psychotherapist, PhD Candidate of the University of Thessaly) spoke on “Self-assistance and empowerment of people with mobility disabilities.”
During the second session the first speaker, Rev. Anargyros Sigalas (Parish Priest, Agioi Pantes Church Kallithea, Athens) presented a paper on “Deaf hearings…meaningful: the example of the parish of deaf people, while Rev. Dr. Konstantinos Papanikolaou (Former Director of IEA, Member of the EASPD Standing Committee on Employment) spoke on the topic “OLYMPIAS, Facilitating the access of people with disabilities to the Church and work through the Internet.” A round table discussion also took place during the conference on the topic “Church and Disability: Obstacles and Bridges” with the participation of Petros Bellos (President of the Association of People with Disabilities in Magnesia, “Ippokampos”), Ioanna Georgiadou (Social Psychologist, Msc, Systemic Psychotherapist), Rev. Georgios Giannos (Parish Priest, The Dormition of the Mother of God church, Metropolis of Demetrias, Member of the writers team of the book manual, “The Religious Lesson in Special Education”), and Dr. Christiana Lappa (Post-doctoral Researcher in Special Education, University of Thessaly, Lecturer at the Hellenic Open University). During the conference all the papers were presented in the sign language while the closing of the conference took place in the morning of Sunday, March 31, with the Divine Liturgy at the Church of Evangelistria in Nea Ionia, Volos, which was also presented in the sign language.

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ERYTECH Presents Findings at European Red Cell Research Society Meeting

Posted by fidest press agency su venerdì, 15 marzo 2019

LYON, France and CAMBRIDGE, Mass., (GLOBE NEWSWIRE) — ERYTECH Pharma (Euronext Paris: ERYP – Nasdaq: ERYP), a clinical-stage biopharmaceutical company developing innovative therapies by encapsulating drug substances inside red blood cells, announced that an oral presentation entitled “Comprehensive proteomic profiling of erythrocytes following hypotonic dialysis-based drug encapsulation process“ will be presented today at the 22nd meeting of the European Red Cell Research Society (ERCS) in Ascona, Switzerland. A poster highlighting the results of this work will also be presented at the ERCS Meeting and will be available on the Company’s website at http://www.erytech.com after March 11, 2019.The lead investigational therapeutic produced using the Company’s ERYCAPS® encapsulation process, eryaspase, consisting of the enzyme L-asparaginase encapsulated inside donor-derived red blood cells, is currently being evaluated in the Phase 3 TRYbeCA-1 trial in metastatic pancreatic cancer. In an earlier 141 patient randomized Phase 2b trial of eryaspase in combination with chemotherapy for the treatment of second-line metastatic pancreatic cancer, significant improvements in overall survival and progression free survival were observed versus chemotherapy alone with no apparent increase in toxicity2.
The erythrocyte proteomic profiling study being presented at the meeting was performed with the participation of the 3P5 Proteomic Platform (at the Paris-Descartes University, France) specialized in high-performance mass spectrometry protein identification and microanalysis. With the exception of L-asparaginase, profiling analysis revealed no significant difference in the proteomic landscape when comparing packed RBCs, ERYCAPS®-processed RBCs without enzyme, and ERYCAPS®-processed RBCs encapsulating L-asparaginase.These results confirm the notion that the ERYCAPS® process does not significantly alter the properties of RBCs and that apart from the encapsulated drug substance, RBC-based therapeutics produced using this process have similar characteristics to that of unprocessed packed RBCs.
ERYTECH plans to advance candidates using the ERYCAPS® platform and to explore the field of RBC-based therapeutics, building on these proteomic results and future findings regarding RBC biology.

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AM Best Withdraws Credit Ratings of The Education Benevolent Society Incorporated

Posted by fidest press agency su domenica, 6 gennaio 2019

AM Best has withdrawn the Financial Strength Rating of B++ (Good) and the Long-Term Issuer Credit Rating of “bbb” of The Education Benevolent Society Incorporated (EBS) (New Zealand) as the company has requested to no longer participate in AM Best’s interactive rating process.On December 31, 2018, EBS completed a portfolio transfer that resulted in all existing insurance obligations at the company being transferred to Union Medical Benefits Society Limited. From January 1, 2019, EBS no longer operates as an insurance company and acts as a marketing organization.AM Best’s procedure is for a final rating opinion to be produced in conjunction with a rating withdrawal. However, because EBS’ balance sheet does not contain any insurance assets or liabilities, AM Best was unable to produce a final rating opinion.
Ratings are communicated to rated entities prior to publication. Unless stated otherwise, the ratings were not amended subsequent to that communication.AM Best is a global rating agency and information provider with a unique focus on the insurance industry. Visit http://www.ambest.com for more information.

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Conscious citizenship: new Maltese citizens give back to society

Posted by fidest press agency su mercoledì, 1 agosto 2018

Chetcuti Cauchi Advocates. Claris Foundation, Chetcuti Cauchi Advocates’ philanthropic arm, inaugurated the reconstruction of a state-of-the-art playground at a children’s home in Malta. This charitable event was officially endorsed by Hon Julia Farrugia Portelli, Parliamentary Secretary for Reforms, Citizenship and Simplification of Administrative Processes.Chetcuti Cauchi Advocates has always been conscious of less fortunate people and willing to devote time and money to give back to society. Thanks to the firm’s commitment to charitable giving and the generosity of its high-net-worth investor clients, Claris Foundation has managed to allocate €70,000 of its funds for the installation of a fully-equipped and modern play area with the aim of providing the children with a safe environment for play, leisure and interaction.Lead partner of the firm’s Residency and Citizenship Practice Group and a member of the Board of Administrators of Claris Foundation, Dr Jean-Philippe Chetcuti encourages aspiring Maltese citizens to contribute towards Claris Foundation. In Dr Chetcuti’s words, “The goal of the Programme is not to accept as many new Maltese citizens as possible; rather, it strives to attract talented individuals of an excellent standing that can contribute not only to our economy but also to the social well-being of the country. For instance, some of our clients have invested in promoting Maltese art abroad; but many contribute to approved charities such as Claris Foundation helping underprivileged children and refugees.”Dr Chetcuti also added that the willingness to give back is relatively common amongst high-net-worth investors we work with, with some 91% of the firm’s international client families supporting a charity of their choice.These views are shared by Hon Julia Farrugia Portelli, who inaugurated the completion of the playground. Hon. Portelli Farrugia observed that “since the inception of the citizenship by investment programme, more than 550 donations have been made by applicants of the programme, with an overwhelming value of €3.5 million.” The positive impact of the programme, according to Ms Farrugia Portelli, is “measured not through monetary means, but through the legacy it is leaving behind.”Dr Maria Chetcuti Cauchi, Chairperson of Claris Foundation and co-founding partner of Chetcuti Cauchi Advocates, joined them in expressing her gratitude towards the international investor community, explaining that donations to Claris Foundation used to previously come from the employees and their family members, however, foreign clients have voluntarily joined them in this mission. “It is through the generosity of such persons as well as the hard work carried out by the employees that this initiative has become a reality,” stated Dr Chetcuti Cauchi at the playground inauguration ceremony.It is also worth mentioning that the philanthropic efforts of the firm, coupled with the generosity of international benefactors, have allowed Claris Foundation to realise a number of other charitable projects, including funding children education under the Jesuit Refugee Services Integration Programme, reconstructing a family home in Albania, and covering the costs of the psychological examination for a student in need. Claris Foundation is a Malta-based charitable organisation established in 2008 with the scope of raising awareness about vulnerable persons in Malta and abroad, as well as for developing and implementing programmes in support of health, education and well-being of children worldwide. Projects embarked on by Claris Foundation include the reconstruction of a family’s home in Albania, financial assistance for a student’s psychological examination, as well as supporting the Jesuit Refugee Services Integration Programme.

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Internet Society Names Andrew Sullivan as New President & CEO

Posted by fidest press agency su domenica, 1 luglio 2018

In advance of its 2018 Annual General Meeting, the Internet Society’s Board of Trustees announced today that it has selected Andrew Sullivan as the organization’s new President and Chief Executive Officer. Sullivan will assume leadership of the global non-profit organization dedicated to promoting the open development, evolution and use of the Internet on 1 September, 2018. As President and CEO, Sullivan will also join the Internet Society’s Board of Trustees.
Sullivan brings many years of experience in the Internet industry to his new role, having worked to enhance the Internet’s value as an open, global platform throughout his career. Among his notable achievements is the launch of the .info Internet top level domain name. While at Dyn, now a Global Business Unit of the Oracle Corporation, he managed the Domain Name System (DNS) development and architecture departments. This led to his appointment to the Internet Architecture Board (IAB) – which oversees the technical evolution of the Internet – where he was elected Chair from 2015-2017.“The Board and I are extremely pleased that Andrew will be leading the Internet Society forward,” said Gonzalo Camarillo, Chair of the Internet Society Board. “Our current President & CEO, Kathy Brown, has laid the foundation for Andrew to increase the Internet Society’s relevance and impact in shaping the future of the Internet. We are confident that he will succeed in leading the organization and its community in working for a more open, globally-connected, secure, and trustworthy Internet for everyone.”With nearly half the world’s population still lacking Internet access, Sullivan will use his new role to address the growing opportunities gap that is opening up between those who have access and those who don’t. “The Internet is now central to so many people’s lives, and world events make the mission of the Internet society more important than ever before,” said Andrew Sullivan. “It is only together that we can ensure that the Internet keeps fulfilling its promise to enrich people’s lives and I can think of no better way to deliver on that promise than as President & CEO of the Internet Society. I am honoured to have been chosen for this role, and will work every day to promote the defining values of an open, trusted Internet.”Sullivan holds a Bachelor of Arts (Hons) from the University of Ottawa, and a Master of Arts degree from McMaster University. His graduate work on the philosophy of economics led him to his interest in free and open source software and open Internet protocols and standards. He now carries that interest and passion forward to his new position at the Internet Society.He will be based in Reston, Virginia.

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World Congress of the International Cartilage Repair Society

Posted by fidest press agency su martedì, 10 aprile 2018

Macau Room Almaty 3, Sheraton Grand Macau Hotel Tuesday, April 10, 2018 12:30 – 13:30 Almaty 3 Room, Lunch Symposium: HYALOFAST One-step Procedure: Best Practice and New Evidence in Cartilage Repair. Moderator: Alberto Gobbi, OASI Bioresearch Foundation, Milano – Italy Speakers: Dr. Bogusław Sadlik, St. Luke Hospital – Bielsko Biala – Poland, Dr. Alberto Gobbi, OASI Bioresearch Foundation, Milano – Italy, Prof. Stephan Nehrer, Danube University, Krems – AustriaAnika Therapeutics, Inc. (NASDAQ: ANIK), a global, integrated orthopedics and regenerative medicines company specializing in therapeutics based on its proprietary hyaluronic acid (“HA”) technology, today announced plans to showcase HYALOFAST®, a biodegradable, HA-based cartilage repair scaffold, at the 14th World Congress of the of the International Cartilage Repair Society (ICRS). The ICRS World Congress, which is being held in Macau, China during April 9-12, 2018, is the world’s largest gathering of scientists, clinicians and industry participants focused on clinical cartilage repair and basic cartilage research.
“HYALOFAST represents a major advancement in the treatment of cartilage injuries and defects, evidenced by the positive reception it has received from physicians across 15 global markets,” said Joseph Darling, President and CEO, Anika Therapeutics. “The ICRS World Congress is the ideal venue to showcase the significant advantages HYALOFAST offers over invasive open surgical techniques and traditional scaffolds, to the largest gathering of cartilage repair specialists from around the world. At this year’s meeting, we’ve developed a robust educational agenda featuring world-renowned thought-leaders with HYALOFAST expertise sharing their technical know-how and providing hands-on, guided training sessions with our custom-built HYALOFAST Virtual Surgical Simulator. We believe that peer-to-peer education and technical training is central to prompting the HYALOFAST trial, which we hope will increase commercial adoption.”
HYALOFAST is a non-woven, single-step, off-the-shelf, biodegradable HA-based scaffold for hyaline-like cartilage regeneration to treat cartilage injuries and defects. HYALOFAST is commercially available in over 15 countries and has been used to successfully treat more than 14,000 patients internationally, and with strong five-year patient follow-up data. HYALOFAST is pending regulatory submission in the United States and its FastTRACK Phase III trial is currently enrolling patients across the U.S. and Europe.

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Smithers Avanza Toxicology Services to Offer Two Presentations at 2018 Society of Toxicology Annual Meeting

Posted by fidest press agency su martedì, 13 marzo 2018

Smithers Avanza Toxicology Services, a contract research organization (CRO) supporting the pharmaceutical and chemical industries, will offer a presentation and poster at this year’s Society of Toxicology (SOT) Annual Meeting to be held March 11-15 in San Antonio, Texas. In addition, several representatives from Smithers Avanza Toxicology Services will be on hand to talk with attendees at booth #1123 in the exposition center.“It’s always an honor to share our information, with industry colleagues and clients,” said Michael Dorato, PhD, DABT, Fellow ATS, Executive Vice President, Smithers Avanza Toxicology Services. “The annual meeting always provides numerous opportunities to share data and best practices while connecting with experts from all over the world.” Dr. Shakil Saghir, Principal Toxicologist, Smithers Avanza Toxicology Services, will present “Use of KMD in Regulatory-Mandated Toxicity Testing of Non-Pharmaceuticals: From Concept to Application” at the roundtable session on Wednesday, March 14 at 4:30 p.m. Smithers Avanza will also feature the poster presentation “Geriatric Toxicology: Understanding Human Relevance of Toxicities Observed at Late-Stage of Long-Term Studies” (Poster Board #P709 in the Exhibit Hall), authored by Dr. Shakil Saghir and Dr. Michael Dorato. Dr. Saghir will be on hand to discuss the poster.For more information about the Smithers Avanza portfolio of services, visit http://smithersavanza.com.

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There is a growing consensus that current narratives around poverty have failed and that a new approach is needed to create a good society

Posted by fidest press agency su venerdì, 28 ottobre 2016

londraLondra. One that requires collective action from government, charities, business and communities and which is willing to try new ways of working. This was the message to come out of an event and special report, organised by the Webb Memorial Trust.
Andrew Curtis, senior programme manager at Oxfam, said: “There is growing consensus that the narratives used in the third sector, however well-meaning and right, have been rejected. Poverty is a term that is politically divisive, creates stigma and is highly contested to the point of still having to persuade people that poverty exists in the UK. We need to create a new way of speaking, to speak with those directly affected not for them, and we need to speak louder.” Olivia Bailey, research director at the Fabian Society, said: “Language matters. Talking about poverty describes the problem but it doesn’t generate enthusiasm for solutions. We need to find a new framework that is a rallying point for people to get behind a raft of policies. The American Dream tapped into that aspiration. We should think about the ‘British Promise’, which should be the security to know if you need help it is there.” Dr Michael Orton, Warwick University Institute for Employment Research, said: “A shared vision means not working in silos. It means consensus building. Working together should be at the core of what we do. Instead of launching into ideological deconstructions of that vision, we should [each] focus on the bits that we can work with.”Rys Farthing, a social policy analyst who specialises in youth and poverty, said: “Our ways of trying to create a world without poverty have been tried and tested and got us this far. We need to try every tactic we can think of to keep winning. Working with children and young people as a solution is a strategy we haven’t tried much yet. It might be a way to find some new pathways to progress.”

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Close the gaps on fundamental inequality

Posted by fidest press agency su venerdì, 24 giugno 2016

pianeta terraGovernments must act now to address economic and social inequalities that divide people and countries, benefiting only a few and forcing the many into cycles of poverty, vulnerability and marginalization, international humanitarian and development network ACT Alliance has said. Commenting as the World Wealth Report from CapGemini was released today, ACT Alliance said that there is an urgent need for governments to close the gap by promoting policies known to lower income and wealth disparities.“Ending inequalities between countries and between people represents addressing issues of justice, issues of human rights, and issues that speak to the kind of society that people want to live in,” said John Nduna, ACT Alliance General Secretary. Questioning the existing economic model, Nduna said: “We need a new paradigm that addresses the root causes of poverty, and policies that offer pathways to progressive taxation and greater wealth distribution.”While there is an unprecedented trend in increasing income inequality within countries for the benefit of a few mega rich individuals, ACT Alliance highlighted that social protection programmes, progressive taxation and equity based structural policies such as the introduction of a minimum wage could play a significant role in reducing the growing gap between rich and poor. ACT Alliance is a coalition of 140 churches and faith-based organisations working together in over 100 countries to create positive and sustainable change in the lives of people in need. ACT works through faith-based networks and communities to help inform and influence justice and rights-based policies at all levels that seek to address the existing gaps in income and other forms of inequality. “Action today could mean that specific targets for equity could be achieved,” said Nduna. “For example, enhanced use of progressive taxation on business, foreign investments, income and wealth, or securing full and productive decent work for all, could have rapid impacts on people most in need. Closing these gaps requires intentional commitments by political leaders, business leaders and ambitious policies from governments at all levels. Without this, there will be no end to the broken economic system that makes a few rich and the majority poor.”
ACT Alliance is part of the Fight Inequality Alliance a group of organisations including ActionAid, Amnesty International, CIVICUS, Femnet, Focus on the Global South, Greenpeace, International Trade Union Confederation (ITUC) and Oxfam.

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Wrong and outdated views towards LGBT people endanger their fundamental rights

Posted by fidest press agency su mercoledì, 16 marzo 2016

fundamental rightsIn some Member States, doctors still view homosexuality as a disease and transsexuality as a mental disorder, according to findings from a new report by the EU Agency for Fundamental Rights (FRA). Such negative views of lesbian, gay, bisexual and trans (LGBT) people in society, among professional groups and policy makers hampers efforts to counter discrimination and hate crime. In the first-ever comparative survey across 19 Member States of the views of public officials, health officials, teachers and police officers, the positive impact of EU initiatives were largely acknowledged. However, they also recognised the lack of information and professional training about the needs of LGBT people prevents them from acting to help counter the discrimination LGBT people continually face.
“LGBT people have the same rights to education, to healthcare and to be treated equally as everyone else. They too have the right to live their life in dignity, free from fear and discrimination,” says FRA Director Michael O’Flaherty. “FRA’s latest findings reveal how some doctors still wrongly believe that homosexuality is a disease. They underscore the need for the EU and its Member States to empower public officials to act on their duty to deliver high quality service to help end the suffering many LGBT people experience.”FRA spoke to the professional groups best placed to identify the barriers and drivers in implementing fundamental rights policies on the ground. Some of the key findings that conseil de l'europeemerged that can be found in the ‘Professionally speaking: challenges to achieving equality for LGBT people’ report include:Society can be hostile view towards LGBT people and professionals can harbour prejudices, such as believing that homosexuality is a disease that can be caught. This points to the need for more positive EU and national awareness-raising campaigns, such as in the EU’s list of actions to improve respect for LGBT people and their rights. All professional groups have low levels of awareness and knowledge about LGBT needs. This underlines the importance of professional training, and civil society partnerships and cooperation to help counter prejudice, especially towards trans people in healthcare, and better deliver the same high level of service that most other people enjoy.The lack of objective information, particularly in schools, can result in bullying and prejudice in later life, and force LGBT youths to hide their sexual orientation/ gender identity. Member States should work with education authorities and schools to formulate targeted campaigns to help make schools a safer and friendlier place for LGBT people.LGBT hate crime often goes unrecognised, unreported and unrecorded. Member States should make more efforts to ensure the laws guarding against hate crime are properly enacted, and that greater efforts are made to improve LGBT hate crime reporting which should be recorded.
The report surveyed public officials, doctors, teachers and police officers about which laws and policies work and which do not, and why, when it comes to protecting and promoting the rights of LGBT people. A comprehensive EU-wide overview of LGBT-relevant laws and policies can be found in a FRA report launched in December 2015. This report also looks at the problems intersex people face.The findings complement the results from FRA’s ground-breaking EU LGBT survey which revealed large-scale fear and discrimination among LGBT people across the EU. The full dataset from the survey will be available later this year.
The EU Agency for Fundamental Rights (FRA) provides evidence-based advice to EU and national decision makers, thereby contributing to more informed and better targeted debates and policies on fundamental rights.

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Alternatives to detention for asylum seekers and forced-return procedures

Posted by fidest press agency su domenica, 11 ottobre 2015

alternativesIn the context of its work in the area of migration, asylum and borders, FRA is today publishing a new paper, Alternatives to detention for asylum seekers and people in return procedures. The paper seeks to provide guidance to policy makers and practitioners on the use of measures for asylum seekers and people in return procedures that do not unnecessarily deprive them of their right to liberty.
Making use of the many alternatives to detention is of advantage both to the hosting state and migrants, as on the one hand they are more cost-effective and on the other they are less intrusive and more respectful of fundamental rights. According to the UN Special Rapporteur on the human rights of migrants, alternatives are far less expensive than detention, not only in the short term but also when it comes to longer-term costs associated with detention, such as the impact on health services or on the integration of migrants into EU society.
For asylum seekers as well as those already on EU territory whose applications for international protection or residence permits have been rejected, detention too often remains the default solution. At the same time, the majority of EU Member States provide for the possibility of alternatives to detention. This FRA paper discusses a number of such alternatives, and lists a number of legal and other instruments together with the general human rights and EU legal framework.The first section of the paper covers the international framework that safeguards the right to liberty, while the following sections focus specifically on alternatives to detention as follows:
Selected instruments on the right to liberty
Selected non-binding United Nations instruments on alternatives to detention
Selected non-binding Council of Europe instruments on alternatives to detention
Selected European Union law provisions relating to alternatives to detention
Selected case law from the European Court of Human Rights, the Court of Justice of the EU and the United Nations Human Rights Committee on alternatives to detention
Recently developed tools
Selected research publications (photo alternatives)

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Fundamental rights and non-discrimination conference in Tirana – final statement

Posted by fidest press agency su lunedì, 24 novembre 2014

tiranaTirana. At the end of the conference on “Fundamental rights, non-discrimination and the protection of vulnerable groups, including LGBTI”, which took place in Albania on 20-21 November 2014, the participating Members of the European Parliament, the Italian Presidency of the Council of the EU and the European Commission issued the following statement:”This conference has shown that enlargement countries have put in place key elements of the legal and policy framework for fundamental rights and non-discrimination. Vulnerable groups, among them LGBTI citizens, nonetheless often remain at risk of discrimination, marginalization or even violence. We encourage governments and political leaders of the region to demonstrate their commitment to ensuring that all minorities and vulnerable groups are accepted and can participate freely in society. They should also ensure that discrimination on the basis of sexual orientation and gender identity is prohibited in law and that persons belonging to minorities can equally exercise their rights. A hierarchy of grounds must be avoided and attention should be paid to multiple forms of discrimination. Finally, sustained efforts are needed to implement and enforce relevant legislation and policies, to adopt pending reforms and to work at changing societal attitudes from prejudice and even hostility to respect and acceptance.”

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Bloccare la proteina TRF2

Posted by fidest press agency su venerdì, 21 novembre 2014

Cancro-sintetizzata-molecola-che-blocca-proteina-tumoraleTRF2 è una proteina strutturale delle regioni terminali dei cromosomi (telomeri), che gioca un ruolo importante nel processo di trasformazione neoplastica. Bloccarla può rappresentare una nuova e valida strategia antitumorale. Un gruppo di ricercatori dell’Istituto Regina Elena (IRE) di Roma, coordinato da Annamaria Biroccio, ha sintetizzato un piccolo peptide in grado di interrompere i segnali cellulari ad attività tumorale di TRF2. Il lavoro è stato pubblicato oggi sulla rivista internazionale Journal of American Chemical Society.
Il progetto multidisciplinare nasce dalla collaborazione con i Chimici dell’università Federico II di Napoli e si fonda sull’osservazione che la proteina TRF2, attraverso il suo dominio TRFH è in grado di convogliare al telomero varie proteine che contribuiscono con la loro attività alla formazione del tumore. I ricercatori, basandosi su dati cristallografici disponibili in letteratura, hanno disegnato e sintetizzato un peptide che, legandosi con alta affinità al dominio TRFH di TRF2, inibisce i segnali coinvolti nel processo di tumorigenesi. Tale molecola non è stata scoperta per caso, ma tramite processi di ingegneria chimica, che hanno permesso la modulazione della sua funzionalità e l’ottimizzazione di determinate proprietà, allo scopo di trovare la molecola giusta.
Questi studi rappresentano il futuro della ricerca. “La bioinformatica – chiarisce Annamaria Biroccio – e nello specifico gli studi predittivi, permetteranno di ottimizzare quei processi che intercorrono tra la fase di ‘disegno’ e quella di selezione dei farmaci a bersaglio molecolare e permetteranno, conseguentemente, di abbattere i tempi e, non ultimo, i costi legati alla sperimentazione.”
“Le moderne tecniche di Rational Design e l’utilizzo di modelli bioinformatica- spiega Pasquale Zizza, primo autore dello studio – hanno consentito il disegno e la selezione di una molecola ad elevato potenziale applicativo in grado di bloccare le funzioni reclutanti di TRF2.”
“I risultati ottenuti – evidenzia Annamaria Biroccio – scaturiscono da uno studio più ampio, in collaborazione con il gruppo francese diretto dal Prof. Eric Gilson, in cui è stato identificato un ruolo non canonico della proteina telomerica TRF2. Il lavoro pubblicato sulla rivista “Nature Cell Biology” a Luglio del 2013, infatti, evidenziava come TRF2 possa contribuire allo sviluppo tumorale, non solo attraverso la sua già nota capacità di mantenere l’integrità telomerica, ma anche attraverso la modulazione di alcuni componenti del sistema immunitario.”“Lo studio appena pubblicato – sottolinea Ruggero de Maria, Direttore Scientifico IRE -rappresenta un esempio di come attraverso un approccio multidisciplinare sia possibile in tempi rapidi passare dall’identificazione di un bersaglio molecolare al disegno di un inibitore specifico.”

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Action needed to ensure that all people with disabilities can vote

Posted by fidest press agency su martedì, 29 aprile 2014

european votePeople with disabilities are active citizens keen to participate in political life given the right opportunities. However, legal, administrative and accessibility barriers can still prevent them from taking part in elections finds the latest research on the rights of people with disabilities from the EU Agency for Fundamental Rights (FRA).“Political participation is a basic right that everyone should enjoy equally,” says FRA Director Morten Kjaerum. “Yet, FRA’s report underlines that many barriers can undermine the democratic rights of people with disabilities. With European elections around the corner, it is timely reminder that across the EU change is needed to allow all people with disabilities to have an equal say in the political life of our society.”Together with the European Commission, FRA developed a set of human rights indicators on how the right to political participation, as described in the UN’s Convention on the Rights of Persons with Disabilities (CRPD), is being respected, promoted and fulfilled across the EU. The data which populate these indicators show that given the opportunity people with disabilities actively participate in politics through voting, political meetings and engaging with elected officials. However, the data also reveal that significant challenges remain which affect some people with disabilities more than others.

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American Chemical Society honors educators making sustainability part of the education of tomorrow’s scientists

Posted by fidest press agency su giovedì, 30 maggio 2013

WASHINGTON The American Chemical Society (ACS) has honored five individuals and teams who have incorporated concepts of sustainability into the chemistry education curricula for future scientists. As part of ACS’ mission to “advance the broader chemistry enterprise and its practitioners for the benefit of Earth and its people,” the Society’s Committee on Environmental Improvement (CEI) has recognized individuals or groups who have made exemplary contributions to the incorporation of sustainability in chemical education. The ACS is especially pleased to note that these awards reflect improvements at all levels of education from K-12 to community colleges to graduate degree programs.“Developing sustainable, chemical solutions to everyday problems — whether they be polymer coatings for solar panels, efficient vehicle batteries that will store energy or methods for purifying drinking water — these discoveries require new ways of thinking,” said ACS President Marinda Li Wu, Ph.D. “ACS is proud to announce that leading chemistry educators are stimulating the next generation of scientists to think in new ways to develop new, environmentally sensitive products and processes so that our Earth can continue to sustain us all.”The winners of the ACS-CEI Award for Incorporation of Sustainability into Chemistry Education:
Richard H. Jarmon, Ph.D., College of DuPage, Glen Ellyn, Ill.
Andrew Jorgensen, Ph.D., University of Toledo, Toledo, Ohio
Resa Kelly, Ph.D., San Jose State University, San Jose, Calif.
Cristina Chang, San Jose State University, San Jose, Calif.
Natalia Pavlovna Tarasova, Ph.D., D. Mendeleev University of Chemical Technology of Russia, Moscow, Russia
Joseph R. Vincente, East Side Community High School, New York, N.Y.
Andrea Swenson, East Side Community High School, New York, N.Y.

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The Conference of European Churches

Posted by fidest press agency su sabato, 20 ottobre 2012

“Though there are many peace activists in the world, who deserve recognition through a prize like this, it does not come as a total surprise that the European Union is awarded with the Nobel Peace Prize. The Conference of European Churches and its Church and Society Commission welcome today’s decision of the Nobel Peace Prize Committee and congratulate all who have contributed to the success of the European integration project,” Rüdiger Noll, Director of the Church and Society Commission of the Conference of European Churches, commented. “The Nobel Peace Prize is a reminder that today’s European Union started as a peace and reconciliation project.”“In as much as the Nobel Peace Prize is a recognition of how successful the European peace and reconciliation process is and was after the devastating effects of two World Wars, the prize is also a challenge for the future. Especially at a time of an economic and financial crisis, the decision of the Nobel Peace Prize Committee should serve as a reminder of the original raison d’être of the European Union and the core values of the European integration process. Most of today’s conflicts are not primarily conflicts between states, but within societies. Poverty, social marginalisation, access to resources and failed integration policies are often root causes for today’s conflicts. In this regard as well as in promoting peace and reconciliation in a global context the European Union has an important role to play,” the CSC Director added.
The Conference of European Churches (CEC) is a fellowship of some 120 Orthodox, Protestant, Anglican and Old Catholic Churches from all countries of Europe, plus 40 associated organisations. CEC was founded in 1959. It has offices in Geneva, Brussels and Strasbourg.
The Church and Society Commission of CEC provides a platform for the CEC membership to reflect on socio-ethical issues ecumenically and to involve them in common action and advocacy in relation to the European Union, the Council of Europe, the North Atlantic Treaty Organisation, the Organisation for Security and Co-operation in Europe and the United Nations (in European matters). CSC operates as a forum for action, dialogue and ecumenical training in European affairs.

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Why science and society don’t understand each other

Posted by fidest press agency su venerdì, 2 marzo 2012

Toronto viewed south from Bloor

Toronto viewed south from Bloor (Photo credit: Small)

Toronto March 4, 2012 – 3:00pm J.J.R. Macleod Auditorium, Medical Sciences Building, University of Toronto, 1 King’s College Circle. (Queen’s Park Subway Station) A talk by Professor Massimiano Bucchi Free admission The Italian Cultural Institute, in collaboration with the Royal Canadian Institute for the Advancement of Science and the University of Western Ontario, is proud to announce an illustrated talk, Of Ducks and Rabbits, Geese, Cats and Dogs: Why Science and Society Don’t Understand Each Other by Professor Massimiano Bucchi (Department of Sociology, University of Trento) for the Sunday Science Lectures series.

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A test for Europe’s foreign policy

Posted by fidest press agency su venerdì, 4 febbraio 2011

From The Economist this week. Every year the German Language Society selects a word of the year and an unword, usually something somebody said but should not have done. Wutbürger (irate citizen) was the word for 2010. The unword was alternativlos (no alternative), as in the bail-out of Greece was alternativlos. These choices capture something of Germany’s mood these days. Wutbürger refers to Germans who are angry about huge infrastructure projects, among other things, and disenchanted with conventional party politics. Alternativlos suggests asense of frustration and resignation.
In 2010 the economy grew at its fastest rate since unication, and unemployment dropped to its lowest level since 1992. Real incomes are rising after years of stagnation. In December 45% of Germans were condent about the coming year and only 11% felt trepidation, says one survey. Other rich countries are studying Germany’s recipe for success with some envy.  In most countries voters would give their government credit. In Germany things are more complicated. Angela Merkel’s coalition, which took oce in October 2009, is widely seen as a disappointment. The three party allianceconsisting of Mrs Merkel’s Christian Democratic Un. The opposition lacks artillery. The SPD is still seeking a remedy that might arrest its long-term decline. Its leader, Sigmar Gabriel, is not a credible alternative to Mrs Merkel. Frank-Walter Steinmeier, the former foreign minister, would be more formidable. But German voters tend to unseat chancellors only when they are angry, not because they embrace the challenger. The Greens could conceivably displace the SPD as the second-strongest party, but they too lack a candidate to match Mrs Merkel. The ex-communist Left Party is a mess. A co- alition of the three left-of-centre parties seems far-fetched. In Mrs Merkel’s camp, chieftains with the stature to challenge her leadership have recently left politics (Christian Wul, the former premier of Lower Saxony, became federal president last year). Their successors lack experience or independent power bases. Karl-Theodor zu Guttenberg, the charismatic defence minister, is Germany’s most popular politician and a potential chancellor. But he is young and his route to the top is through the CSU. His handling of a series of minor scandals has dulled his sheen, at least temporarily.  The strong economy will buoy Mrs Merkel, even if earlier governments deserve more credit for it than the present one. Less obviously, she may benet from pockets of rage and resignation. Her administration has looked more purposeful ever since it challenged rebels against an ambitious rail project in Stuttgart, the original Wutbürger. The CDU brands them enemies of progress and mocks the Greens, political home to many rebels, as the party of no.
When Mrs Merkel sees no alternative, people tend to believe her. She has been through politically roughpatches and may encounter more. She has been damned for maintaining radio silence rather than sending clear messages, for balancing factions rather than leading, for leaning left when her party yearned for a rightward tilt. She will be tested by seven regional elections this year. The results could wound her. But, for now at least, Mrs Merkel seems to be alternativlos
Editor’s highlights
Like the rest of the world, we are transfixed by events in Egypt. Over ten days, the country has passed through an intense arc of emotion, from fear of autocracy through euphoria to fear of chaos. Many in the West and the region fear the consequences of the regime’s collapse. But we believe the events there are to be welcomed. The uprising has given a downtrodden region a taste of freedom and holds out the prospect of democracy in the Arab world; and, in the end, democracy is the only real guarantor of stability. Also in this week’s issue:
Japan’s radical prime minister: Naoto Kan puts together an impressive package of reforms
The pirate boom: Time to tackle the menace in the seas off Somalia
Londonism and its adherents: The capital’s ideology
The masochism tango: How pain assuages guilt

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Society for International Development

Posted by fidest press agency su venerdì, 17 dicembre 2010

Roma 17 dicembre 2010 – ore 14, 30 Via Panisperna 207, Sala Conferenze SID – Society for International Development La Cooperazione Italiana allo Sviluppo – Ministero Affari Esteri e l’OIM – Organizzazione Internazionale per le Migrazioni sono liete di invitarla al Workshop Conclusivo per la presentazione dei risultati raggiunti e dei progetti avviati dal programma MIDA Somalia.  MIDA Somalia è un’iniziativa rivolta ad Associazioni di Donne Somale in Italia, a esponenti della società civile, ONG, istituzioni locali italiane e somale.  Il Progetto ha  promosso il coinvolgimento diretto della diaspora somala in Italia per la messa a punto di iniziative concrete volte a contribuire allo sviluppo socio economico della Somalia e a ridare energia  a una società lacerata da quasi venti anni di conflitto. Programma:
ore 14.30  Saluti istituzionali, presentazione della rete Wadajir, presentazione dei progetti in Somaliland e intervento degli enti locali
ore 17.30   Consegna attestati di partecipazione al corso di formazione MIDA Somalia
ore 18.00   Cocktail e mostra fotografica sulla Somalia

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The Social Policy of Europe

Posted by fidest press agency su martedì, 25 maggio 2010

The European Commission must propose legislation that would combat social inequalities, and  create conditions for a convergence of social insurance and welfare systems in all member  states. This would cover salaries and pensions, and would establish “floors” and “ceilings” for  social benefits. The EU should create a mechanism to monitor member states’ social policies and, if needed, should issue binding recommendations for member states to ensure that the EU moves closer to a common EU social system. The EU should ensure compliance with existing anti-discrimination regulations, in particular  those which deal with gender equality, and which focus on the elderly and people with special  needs, thus ensuring their active and continued role in the labour market and in society.  The EU should increase social protection for vulnerable members of society in all phases of life,  such as elderly people, the disabled or poorer members of society, homeless and unemployed, as well as carers. It should rate countries’ spending of GDP and impose enforceable targets for  member states in the fight against poverty. These measures should be given particular attention  in times of economic recession. In order to rejuvenate its population, the EU should encourage Member States to develop policies to support families, for instance providing support for stay-at-home parents, including financial support, child benefits or fiscal incentives for larger families. Special attention should be afforded to single-parent families and large families. The EU has to work on a better balance between work and family for all. It should enable parents and other citizens with nursing tasks, enabling them to fully participate in working life,  by investing in day-, late-afternoon and night-kindergartens, parental leave and retraining. The EU should formulate minimum standards on these issues.  The EU should ensure that all Member State have equal and truly borderless status despite  their peripheral geographical location. It should do this by ensuring that all travel taxes are removed/revised, by regulating travel to isolated member states to avoid over-dependence on particular transport providers and by providing assistance to reduce the burden for passengers and traders which arise from additional transport and travel costs.

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