Fidest – Agenzia giornalistica/press agency

Quotidiano di informazione – Anno 31 n° 259

Posts Tagged ‘tissue’

“Issue with Tissue”

Posted by fidest press agency su venerdì, 22 febbraio 2019

A new report takes the largest tissue companies to task for destroying North American forests and exacerbating the world’s climate crisis. “The Issue with Tissue” reveals Procter & Gamble, Kimberly-Clark, and Georgia-Pacific use zero recycled content in their toilet paper, instead relying on ancient trees clear-cut from the Canadian boreal forest (the “Amazon of the North”). The report by the Natural Resources Defense Council (NRDC) and Stand.earth includes a scorecard grading the sustainability of toilet paper and other tissue products. The average American uses three rolls of toilet paper a week – and major brands’ refusal to create more sustainable products makes consumers unwittingly complicit in flushing forests down the toilet.This destructive “tree-to-toilet pipeline” does massive harm to Indigenous Peoples and iconic species like the boreal caribou and Canada lynx. Canada’s boreal forest also stores nearly two times as much carbon as is in all the world’s recoverable oil reserves combined. Toilet paper and tissue manufacturers continue to rely on forests even though they have the resources and means to create and deliver products with recycled and responsibly sourced content that are better for the planet.The NRDC/Stand.earth report features a sustainability-based scorecard for at-home tissue brands, assigning “F” grades to such leading U.S. toilet paper brands as Charmin, Quilted Northern, and Angel Soft. Brands using recycled paper content, including 365, Seventh Generation, and Natural Value were among those awarded “A” grades in the report. The NRDC/Stand.earth scorecard also ranks facial tissues and paper towels.
The Canadian boreal is a vast landscape of coniferous, birch, and aspen trees. It contains some of the last of the world’s remaining intact forests, and is home to over 600 Indigenous communities, as well as boreal caribou, pine marten, and billions of songbirds. The loss of intact boreal forest is impacting Indigenous Peoples’ ways of life and driving the decline of caribou and other species.Fortunately, solutions to the tree-to-toilet pipeline already exist. Instead of relying on virgin fiber from ancient forests, tissue companies can use recycled content or sustainably sourced alternative fibers. Use of these materials to create tissue can dramatically reduce our destructive impact on the boreal and other forests in North America and around the world.
NRDC and Stand.earth are calling on Procter & Gamble and other toilet paper and tissue manufacturers to shift to recycled content and sustainable alternative fibers, and to take additional steps to ensure their supply chain is fully protective of boreal caribou habitat and respects Indigenous Peoples’ rights to their lands. Now is the time for action to mitigate the climate crisis and protect the world’s remaining forests, rather than flushing our vital forest ecosystems away.

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AgeX Therapeutics Identifies Genes Implicated in Tissue Regeneration and Cancer

Posted by fidest press agency su mercoledì, 3 gennaio 2018

cancerAgeX Therapeutics, Inc. (AgeX), a subsidiary of BioTime, Inc. (NYSE American: BTX), today announced a newly-published peer-reviewed study that reveals genes implicated in tissue regeneration, cancer, and aging. The study, by scientists at AgeX and BioTime, in collaboration with Insilico Medicine, utilized artificial intelligence (AI) technology to parse millions of gene expression data points to decipher the complex mechanisms controlling natural tissue regeneration. The results, published in the peer-reviewed scientific journal Oncotarget, showed that the candidate genes are expressed differently in tissues early in development when they are capable of regeneration compared to later in life when regeneration can no longer take place. Surprisingly, some of the genes, including one highlighted in the study, COX7A1, displayed a rare profile of being nearly universally dysregulated in diverse types of cancer. The discoveries may lead to novel strategies to induce Tissue Regeneration (iTRTM) in the context of trauma or age-related degenerative disease, as well as treat and diagnose cancer.“It is rare to find genes implicated in tissue regeneration, let alone with abnormal expression in so many diverse cancer types such as those of the breast, lung, kidney, bone, and muscle,” said Michael D. West, PhD, CEO of AgeX and co-CEO of BioTime. “AgeX has certain rights to use the associated patent applications and to commercialize related therapeutic and diagnostic applications. Since we believe unlocking the natural ability of the human body to regenerate tissues afflicted with degenerative disease is a very large market opportunity, we are aggressively developing products using the technology.”A short video is available online describing the discovery and its implication for product development at AgeX. Included in the video is a discussion of an iTR product designated RenelonTM, which, in its first generation form, utilizes a repurposed drug and may therefore have a relatively short development timeline.“The embryonic-to-fetal transition (EFT) deciphered in this study is emerging as a wonderful new arena in which to explore the enhancement of regenerative capacity in old age, which is the core of AgeX’s mission,” said Aubrey de Grey, PhD, VP of New Technology Discovery at AgeX. “The discovery of a subunit of the respiratory chain as a key EFT marker dovetails this research fascinatingly with age-related changes in mitochondrial function, which have long been a priority in the anti-aging field and in my own work.”“BioTime and AgeX Therapeutics are at the forefront of regenerative medicine,” commented Alex Zhavoronkov, PhD, CEO of Insilico Medicine. “By utilizing their heavy investment in large-scale, highly-controlled experiments and their unique expertise in regenerative medicine we managed to develop the AI-powered system for cell and tissue sample profiling. We utilized this system to identify the important genes implicated in the EFT, and possibly in aging. This collaboration started in 2015 when deep leaning methods were in their infancy and required two years to diligently validate the outcomes. We learned that domain expertise is just as important as expertise in AI.”

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